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Browse our anti-GLI2 (GLI2) Antibodies

Full name:
anti-GLI Family Zinc Finger 2 Antibodies (GLI2)
On www.antibodies-online.com are 67 GLI Family Zinc Finger 2 (GLI2) Antibodies from 16 different suppliers available. Additionally we are shipping GLI2 Kits (14) and and many more products for this protein. A total of 86 GLI2 products are currently listed.
Synonyms:
AW546128, GLI2/GLI4, GLI3, HPE9, THP1, THP2
list all antibodies Gene Name GeneID UniProt
GLI2 2736 P10070
GLI2 304729  
GLI2 14633 Q0VGT2

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Top referenced anti-GLI2 Antibodies

  1. Human Polyclonal GLI2 Primary Antibody for IHC, WB - ABIN2777474 : Ikram, Neill, Regl, Eichberger, Frischauf, Aberger, Quinn, Philpott: GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter. in The Journal of investigative dermatology 2004 (PubMed)
    Show all 23 references for ABIN2777474

  2. Chimpanzee Polyclonal GLI2 Primary Antibody for EIA, IHC (p) - ABIN401285 : Roessler, Ermilov, Grange, Wang, Grachtchouk, Dlugosz, Muenke: A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2. in Human molecular genetics 2005 (PubMed)
    Show all 6 references for ABIN401285

  3. Mouse (Murine) Polyclonal GLI2 Primary Antibody for EIA, IHC (p) - ABIN401282 : McDermott, Gustafsson, Elsam, Hui, Emerson, Borycki: Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation. in Development (Cambridge, England) 2004 (PubMed)
    Show all 4 references for ABIN401282

  4. Human Polyclonal GLI2 Primary Antibody for ELISA, WB - ABIN185585 : Haycraft, Banizs, Aydin-Son, Zhang, Michaud, Yoder: Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. in PLoS genetics 2005 (PubMed)

More Antibodies against GLI2 Interaction Partners

Human GLI Family Zinc Finger 2 (GLI2) interaction partners

  1. GLI2 stabilized glial cell missing-a, a pivotal transcriptional factor for trophoblastic syncytialization.

  2. The results do not support our hypothesis that common germline genetic variants in the GLI2 genes is associated with the risk of developing medulloblastoma.

  3. GLI1 (show GLI1 Antibodies) and GLI2, but not GLI3 (show GLI3 Antibodies) are involved in the regulation of SOX18 (show SOX18 Antibodies) gene expression in cervical carcinoma cell lines.

  4. GLI2 mutations typically result in pituitary anomalies with or without postaxial polydactyly.

  5. Rab23 (show RAB23 Antibodies) is expressed in breast cancer cells, and ectopic expression of Rab23 (show RAB23 Antibodies) inhibits the growth and proliferation as well as induces cell apoptosis in breast cancer cells These effects may be due to the inhibition by Rab23 (show RAB23 Antibodies) of Gli1 (show GLI1 Antibodies) and Gli2 mRNA expression

  6. Serum starvation significantly up-regulated the expression of Gli1 (show GLI1 Antibodies), which in turn increased its key target cIAP2 (show BIRC3 Antibodies) expression and enhanced NF-kappaB (show NFKB1 Antibodies)/cIAP2 (show BIRC3 Antibodies) pathway, resulting in promoting cell survival under serum starvation

  7. Identify mutations that increase GLI (show GLI1 Antibodies) activity in patients with Hirschsprung disease.

  8. the JQ1-resistant cells remain dependent on c-MYC (show MYC Antibodies) that now becomes co-regulated by high levels of GLI2

  9. GLI1 (show GLI1 Antibodies)/2 expression is a negative prognostic factor and might represent a novel druggable target in acute myeloid leukemia (show BCL11A Antibodies).

  10. A relatively high frequency of GLI2 mutations occur in patients with congenital growth hormone (show GH1 Antibodies) deficiency. [Review]

Cow (Bovine) GLI Family Zinc Finger 2 (GLI2) interaction partners

  1. Data indicate that the expression levels of transcription factors Gli1 (show GLI1 Antibodies) and Gli2 in muscle were the lowest of the 13 tissues.

Pig (Porcine) GLI Family Zinc Finger 2 (GLI2) interaction partners

  1. The 12 SNPs of GLI2 encompassing exon 4 to exon 8 showed strong association with in the anorectal atresia in pigs.

Mouse (Murine) GLI Family Zinc Finger 2 (GLI2) interaction partners

  1. Study suggested that loss of Gli2 mRNA mediated the anterior-restricted defect in conditional Dicer (show DICER1 Antibodies) knockdown mice and showed that miR (show MLXIP Antibodies)-106b positively regulated Gli2 mRNA expression

  2. Sufu (show SUFUH Antibodies) deletion early in embryogenesis resulted in unstable Gli2 and Gli3 (show GLI3 Antibodies) activity, leading to the ectopic activation of Shh (show SHH Antibodies) signaling.

  3. the three GLI (show GLI1 Antibodies) factors(GLI1 (show GLI1 Antibodies), GLI2, and GLI3 (show GLI3 Antibodies)) in mature hepatocytes form an interactive transcriptional network that is involved in the control of target genes associated with metabolic zonation as well as with lipid and drug metabolism

  4. Gli2 protein expression is downregulated during neural tube patterning, regulating Shh (show SHH Antibodies) signaling. Shh (show SHH Antibodies)-induced upregulation of Gli2 transcription prevents Gli (show GLI1 Antibodies) activity levels from adapting in a different cell type.

  5. GLI2 binds to the IL-6Ralpha (show IL6R Antibodies) promoter and regulates its activity as well as the expression of this receptor.

  6. The results uncover that both Shh (show SHH Antibodies)/Gli2 and Shh (show SHH Antibodies)/Gli3 (show GLI3 Antibodies) signals are required for proper development of murine placentas and are possibly essential for pregnant maintenance.

  7. While darinaparsin ameliorated fibrosis in WT and Gli1 (show GLI1 Antibodies)-KO mice, it was not effective in conditional Gli2-KO mice, supporting GLI2 as a direct darinaparsin target.

  8. The ciliary localization of Gli2 is crucial for cilium-dependent activation of Hedgehog (show SHH Antibodies) signaling.

  9. Systematic analysis in ESCs (show NR2E3 Antibodies) reveals that distinct regions of Gli2 regulate its nuclear and ciliary localization.

  10. The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog (show SHH Antibodies) or GLI2 haploinsufficiency in the mouse.

GLI2 Antigen Profile

Antigen Summary

This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Alternative names and synonyms associated with GLI2

  • GLI-Kruppel family member GLI2 (LOC100359289) antibody
  • GLI family zinc finger 2 (GLI2) antibody
  • GLI family zinc finger 2 (Gli2) antibody
  • GLI-Kruppel family member GLI2 (Gli2) antibody
  • AW546128 antibody
  • GLI2/GLI4 antibody
  • GLI3 antibody
  • HPE9 antibody
  • THP1 antibody
  • THP2 antibody

Protein level used designations for GLI2

GLI-Kruppel family member GLI2 , glioma-associated oncogene family zinc finger 2 , oncogene GLI2 , tax helper protein 1 , tax helper protein 2 , tax-responsive element-2 holding protein , tax-responsive element-25-bp sequence binding protein , zinc finger protein GLI2 , Zn finger transcription factor , zinc finger protein GLI3 , Tax helper protein

GENE ID SPECIES
100359289 Oryctolagus cuniculus
2736 Homo sapiens
304729 Rattus norvegicus
459582 Pan troglodytes
510255 Bos taurus
395956 Gallus gallus
100682984 Canis lupus familiaris
100520334 Sus scrofa
14633 Mus musculus
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