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Browse our anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2) Antibodies

Full name:
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Antibodies (ABCC2)
On www.antibodies-online.com are 55 ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2) Antibodies from 15 different suppliers available. Additionally we are shipping ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Proteins (9) and ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Kits (2) and many more products for this protein. A total of 67 ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 products are currently listed.
Synonyms:
Abc30, AI173996, Cmoat, cMRP, DJS, Mrp2
list all antibodies Gene Name GeneID UniProt
ABCC2 1244 Q92887
ABCC2 12780 Q8VI47
ABCC2 25303 Q63120

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All available anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Antibodies

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Top referenced anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Antibodies

  1. Human Monoclonal ABCC2 Primary Antibody for ELISA, WB - ABIN4948190 : Takahashi, Miura, Scott, Kagaya, Kameoka, Tagawa, Saitoh, Fujishima, Yoshioka, Hirokawa, Sawada: Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia. in Journal of human genetics 2010 (PubMed)
    Show all 5 references for ABIN4948190

  2. Mouse (Murine) Polyclonal ABCC2 Primary Antibody for WB - ABIN610784 : Cockcroft, Thomas, Fensome, Geny, Cunningham, Gout, Hiles, Totty, Truong, Hsuan: Phospholipase D: a downstream effector of ARF in granulocytes. in Science (New York, N.Y.) 1994 (PubMed)
    Show all 5 references for ABIN610784

  3. Human Monoclonal ABCC2 Primary Antibody for IHC (fro), IF - ABIN1105169 : Peng, Yanagida, Chen, Han: Ellipsoidal TiO2 hierarchitectures with enhanced photovoltaic performance. in Chemistry (Weinheim an der Bergstrasse, Germany) 2012 (PubMed)
    Show all 4 references for ABIN1105169

  4. Human Monoclonal ABCC2 Primary Antibody for IHC (fro), IF - ABIN1105167 : Paulusma, Bosma, Zaman, Bakker, Otter, Scheffer, Scheper, Borst, Oude Elferink: Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 4 references for ABIN1105167

  5. Human Monoclonal ABCC2 Primary Antibody for IHC (fro), IF - ABIN1105168 : Kool, de Haas, Scheffer, Scheper, van Eijk, Juijn, Baas, Borst: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. in Cancer research 1997 (PubMed)
    Show all 2 references for ABIN1105168

More Antibodies against ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Interaction Partners

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2) interaction partners

  1. ABCC2 polymorphisms were associated with hematological toxicity in non-small cell lung cancer patients.

  2. Meta-analysis. The ABCC2 c.-24C>T polymorphism increases the risk of resistance to antiepileptic drugs.

  3. we have investigated the role of ABCB1 (show ABCB1 Antibodies) rs1045642 and rs2032582 and ABCC2 rs2273697 and rs717620 in antiepileptic drug-resistance. Our study suggests that the ABCC2 rs717620 polymorphism is associated with resistance to antiepileptic drugs in Chinese patients with epilepsy.

  4. A novel deletion in ABCC2 gene was identified in families with dual hereditary jaundice.

  5. Resveratrol-3-O-sulfate reduced in both MRP2-overexpressing MDCKII-UGT1A1 (show UGT1A1 Antibodies) cells and Human UGT1A9 (show UGT1A9 Antibodies)-overexpressing HeLa cells.

  6. A thalassemia patient has been found to be a carrier of UGT1A1 (show UGT1A1 Antibodies) and ABCC2 polymorphisms explaining a possible reduction of desferasirox metabolism together with a reduction of biliary elimination by MRP2 and causing a serious adverse reaction.

  7. ABCC2 expression in PBMCs may be, in part, influenced by gender, and that at least two endogenous control genes should be utilized.

  8. Activation of liver PKCs during cholestasis leads to Ezrin (show EZR Antibodies) Thr567 phosphorylation resulting in MRP2 internalization and degradation where ubiquitin ligase E3 GP78 (show AMFR Antibodies) is involved.

  9. These studies identify Akt2 (show AKT2 Antibodies) as a critical kinase that regulates radixin (show RDX Antibodies) phosphorylation and leads to Mrp-2 translocation and function.

  10. MRP2 expression in HepG2 cells is repressed by IL-18 (show IL18 Antibodies).

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2) interaction partners

  1. Deficiency in Mrp2 lowers platinum excretion and increases susceptibility to kidney injury, which can be rescued by the human MRP2 ortholog.

  2. In Bcrp1;Mrp2;Mrp3(-/-), but not Bcrp1;Mdr1a/b;Mrp(-/-) mice.

  3. Cd or H(2)O(2) exposure increased the expression of key transport genes, Mrp1 (show ABCC1 Antibodies) and Mrp2, in WT cells but not in metallothionein (show MT Antibodies)-null cells.

  4. hepatic transporters Ntcp (show SLC10A1 Antibodies) and Mrp2 are downregulated in rodent models of necrotizing enterocolitis

  5. Both Abcc2 and Abcc3 (show ABCC3 Antibodies) significantly influenced the PK properties of MTX (show MTX1 Antibodies).

  6. hyperosmotic cholestasis is triggered by a NADPH oxidase (show NOX1 Antibodies)-driven reactive oxygen species formation that mediates Fyn (show FYN Antibodies)-dependent retrieval of the Mrp2 and Bsep (show ABCB11 Antibodies) from the canalicular membrane, which may involve an increased cortactin (show CTTN Antibodies) phosphorylation.

  7. Strain- and sex-dependent circadian patterns in abcc2 expressions displayed robust relations with the chronotolerance of ileum mucosa for irinotecan

  8. In ABCC2-deficient mice impaired ABCC2 function is associated with a significant increase in erythromycin metabolism.

  9. Membrane vesicles prepared from human erythrocytes, which express the MRP2 have important implications for the Selenium-dependent and -independent disposition of Arasenic.

  10. NHERF-1 (show SLC9A3R1 Antibodies) binds to Mrp2, and plays a critical role in the canalicular expression of Mrp2 and its function as a determinant of glutathione-dependent, bile acid-independent bile flow

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine\; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.

Alternative names and synonyms associated with ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2)

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2) antibody
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2) antibody
  • ATP-binding cassette, subfamily C (CFTR/MRP), member 2 (Abcc2) antibody
  • Abc30 antibody
  • AI173996 antibody
  • Cmoat antibody
  • cMRP antibody
  • DJS antibody
  • Mrp2 antibody

Protein level used designations for ABCC2

ATP-binding cassette sub-family C member 2 , canalicular multidrug resistance protein , canalicular multispecific organic anion transporter 1 , multidrug resistance-associated protein 2 , multidrug resistance protein 2 , ATP-binding cassette, sub-family C (CFTR/MRP), member 2 , calicular multispecific organic anion transporter , multidrug resistance associated protein 2

GENE ID SPECIES
1244 Homo sapiens
12780 Mus musculus
25303 Rattus norvegicus
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