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Browse our anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) Antibodies

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anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 Antibodies (SERPINA7)
On www.antibodies-online.com are 116 serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) Antibodies from 17 different suppliers available. Additionally we are shipping serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 Kits (43) and serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 Proteins (34) and many more products for this protein. A total of 198 serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 products are currently listed.
Synonyms:
C730040N12Rik, TBG, THYROXINE-BINDING GLOBULIN
list all antibodies Gene Name GeneID UniProt
SERPINA7 331535  
SERPINA7 6906 P05543
SERPINA7 81806 P35577

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Top referenced anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 Antibodies

  1. Human Polyclonal SERPINA7 Primary Antibody for WB - ABIN1881790 : Mori, Miura, Takeuchi, Igarashi, Sugiura, Saito, Oiso: Gene amplification as a cause of inherited thyroxine-binding globulin excess in two Japanese families. in The Journal of clinical endocrinology and metabolism 1996 (PubMed)
    Show all 6 references for ABIN1881790

  2. Human Monoclonal SERPINA7 Primary Antibody for ELISA, WB - ABIN1724893 : Duhan, Patston: Explanation for the high heat stability of thyroxine binding globulin-Chicago. in Endocrine regulations 2010 (PubMed)
    Show all 2 references for ABIN1724893

  3. Human Monoclonal SERPINA7 Primary Antibody for ICC, FACS - ABIN1724894 : Yan, Yan, Ou: Human thyroxine binding globulin (TBG) promoter directs efficient and sustaining transgene expression in liver-specific pattern. in Gene 2012 (PubMed)
    Show all 2 references for ABIN1724894

  4. Human Polyclonal SERPINA7 Primary Antibody for FACS, IHC (p) - ABIN390670 : Domingues, Font, Sobrinho, Bugalho: A novel variant in Serpina7 gene in a family with thyroxine-binding globulin deficiency. in Endocrine 2009 (PubMed)

More Antibodies against serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 Interaction Partners

Mouse (Murine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) interaction partners

  1. the TBG promoter has a role in sustaining transgene expression in liver-specific pattern

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) interaction partners

  1. mutation in a liver-specific enhancer region of the TBG gene caused inherited TBG deficiency. To our knowledge, the present study is the first report of an inherited endocrine disorder caused by a mutation in an enhancer region.

  2. TBG allosteric regulation is entropy driven. The presence of multiple S states may allow more efficient T4 release due to protease activity.

  3. the TBG promoter has a role in sustaining transgene expression in liver-specific pattern

  4. Freshly isolated TBG-Chicago exists in loop expelled conformation. At 37C, the protein readily converts to a more stable loop inserted conformation with enhanced heat stability.

  5. an intragenic A/G polymorphism (125 bp upstream from exon 2) was identified. complete TBG deficiency was homozygous for the polymorphic TBG allele.

  6. Two novel variants in the thyroxine-binding globulin gene behind the diagnosis of TBG deficiency. homozygous. One involved codon 23 (TCA-->TAA) and the other, codon 223.

  7. Loop variants of the serpin thyroxine-binding globulin: implications for hormone release upon limited proteolysis.

  8. guanine deletion at position 1711, codon 201 (Asp (show ASIP Antibodies)) in exon 2 (GAC (show GLS Antibodies) --> AC) led to a frame shift and premature termination at codon 206, causing a short TBG protein of 205 amino acids (AA) compared to 395 AA of the normal TBG.

  9. new serpina7 gene variant in three members of the same family results in the replacement of the normal asparagine 233 by isoleucine and, subsequently, in disruption of a glycosylation site

  10. The first exon (exon 0) is a short noncoding sequence located 1.62 kilobase pairs (kbp (show KIAA1279 Antibodies)) upstream from exon 1. HNF-1 (show HNF1A Antibodies) site (located 65 bp upstream of the TSS (show RPL38 Antibodies)) is required for the hepatocyte specific expression of the hTBG gene.

Pig (Porcine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) interaction partners

  1. polymorphism in exon 2 in thyroxine-binding globulin is a candidate for the causative variation affecting testis size in boars.

serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) Antigen Profile

Antigen Summary

There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Alternative names and synonyms associated with serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7)

  • serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (Serpina7) antibody
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (SERPINA7) antibody
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (Serpina7) antibody
  • C730040N12Rik antibody
  • TBG antibody
  • THYROXINE-BINDING GLOBULIN antibody

Protein level used designations for SERPINA7

T4-binding globulin , serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antipeptidase, antitrypsin), member 7 , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 , serpin A7 , thyroxine-binding globulin , thyroxin-binding globulin , serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 , serine (or cysteine) proteinase inhibitor clade A (alpha-1 antiproteinase antitrypsin) member 7 , serine (or cysteine) proteinase inhibitor, clade A, member 7

GENE ID SPECIES
331535 Mus musculus
6906 Homo sapiens
81806 Rattus norvegicus
282518 Bos taurus
481007 Canis lupus familiaris
397125 Sus scrofa
443462 Ovis aries
465791 Pan troglodytes
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