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Browse our anti-IRF1 (IRF1) Antibodies

Full name:
anti-Interferon Regulatory Factor 1 Antibodies (IRF1)
On are 123 Interferon Regulatory Factor 1 (IRF1) Antibodies from 20 different suppliers available. Additionally we are shipping IRF1 Proteins (23) and IRF1 Kits (17) and many more products for this protein. A total of 173 IRF1 products are currently listed.
AU020929, Irf-1, IRF1, irf11, MAR, zgc:103566, zgc:136945

Most Popular Reactivities for anti-IRF1 (IRF1) Antibodies

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anti-Human IRF1 Antibodies:

anti-Mouse (Murine) IRF1 Antibodies:

anti-Rat (Rattus) IRF1 Antibodies:

All available anti-IRF1 Antibodies

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Top referenced anti-IRF1 Antibodies

  1. Human Monoclonal IRF1 Primary Antibody for WB - ABIN393910 : Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: Dengue hemorrhagic fever is associated with polymorphisms in JAK1. in European journal of human genetics : EJHG 2010 (PubMed)
    Show all 5 references for ABIN393910

  2. Human Polyclonal IRF1 Primary Antibody for EIA, WB - ABIN952946 : Matsuzaki, Ishizuka, Hisada, Aoki, Komachi, Ichimonji, Utsugi, Ono, Koga, Dobashi, Kurose, Tomura, Mori, Okajima: Lysophosphatidic acid inhibits CC chemokine ligand 5/RANTES production by blocking IRF-1-mediated gene transcription in human bronchial epithelial cells. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 5 references for ABIN952946

  3. Human Polyclonal IRF1 Primary Antibody for EIA, WB - ABIN952945 : Antonios, Rousseau, Larangé, Kerdine-Römer, Pallardy: Mechanisms of IL-12 synthesis by human dendritic cells treated with the chemical sensitizer NiSO4. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 5 references for ABIN952945

  4. Human Monoclonal IRF1 Primary Antibody for IF, WB - ABIN968724 : Cha, Sims, Romine, Kaufmann, Deisseroth: Human interferon regulatory factor 1: intron-exon organization. in DNA and cell biology 1992 (PubMed)
    Show all 3 references for ABIN968724

  5. Cow (Bovine) Polyclonal IRF1 Primary Antibody for WB - ABIN2777249 : Kamitani, Ohbayashi, Ikeda, Togi, Muromoto, Sekine, Ohta, Ishiyama, Matsuda: KAP1 regulates type I interferon/STAT1-mediated IRF-1 gene expression. in Biochemical and biophysical research communications 2008 (PubMed)

  6. Chicken Polyclonal IRF1 Primary Antibody for WB - ABIN2780408 : Kumar, Kumar, Michael, Brabant, Parissenti, Ramana, Xu, Parrillo: Human serum from patients with septic shock activates transcription factors STAT1, IRF1, and NF-kappaB and induces apoptosis in human cardiac myocytes. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against IRF1 Interaction Partners

Human Interferon Regulatory Factor 1 (IRF1) interaction partners

  1. MiR (show MLXIP Antibodies)-23a downregulates the expression of IRF-1 in HCC (show FAM126A Antibodies) cells.

  2. the interactions of IRF1, IFN-beta (show IFNB1 Antibodies) and IRF5 (show IRF5 Antibodies) are involved in the M1 polarization of macrophages and have antitumor functions.

  3. rs56288038 (C/G) in IRF-1 3'UTR (show UTS2R Antibodies) acted as a promotion factor in gastric cancer development through enhancing the regulatory role of miR (show MLXIP Antibodies)-502-5p in IRF-1 expression.

  4. An IRF-1 shorter splicing transcript has been identified in acute promyelocytic leukemia (show PML Antibodies) cells dispalying similar transactivation activity to the full length transcript.

  5. Data suggest that interferon beta (IFN-beta (show IFNB1 Antibodies)) might be involved in modulating the expressions of interferon regulatory factor 1 (IRF1) and interferon regulatory factor-5 (show IRF5 Antibodies) protein (IRF5 (show IRF5 Antibodies)) as well as maintaining the M1 polarization status and its function.

  6. IRF1 upregulation in fetal membranes and myometrium after term labor indicates a proinflammatory role for IRF1 in human parturition. IRF1 is involved in TLR- and cytokine-mediated signaling in human myometrium.

  7. 5AZ had a protective effect after MI by potentiation of IRF1 sumoylation and is suggested as a novel therapeutic intervention for cardiac repair.

  8. IRF1 is a transcriptional regulator of IRG1 in human macrophages.

  9. Data show that ectopic expression of interferon regulatory factor 1 (IRF-1) reduces NF-kappa B (show NFKB1 Antibodies) activity and suppresses TNF receptor-associated factor 2 (TRAF2 (show TRAF2 Antibodies)) and inhibitor of apoptosis 1 (show BIRC2 Antibodies) protein (cIAP1 (show BIRC2 Antibodies)) expression in breast cancer cells.

  10. Gene expression meta-analysis reveals immune response convergence on the IFNgamma-STAT1 (show STAT1 Antibodies)-IRF1 axis and adaptive immune resistance mechanisms in lymphoma

Pig (Porcine) Interferon Regulatory Factor 1 (IRF1) interaction partners

  1. Given these results, porcine IRF1 plays potential roles in cellular antiviral responses against swine viruses.

  2. In a healthy swine model, elevated levels of endothelial IRF-1 were also observed within atherosusceptible regions of the aorta by Western blot analysis and immunohistochemistry, implicating arterial hemodynamics in the regulation of IRF-1 expression.

  3. The results suggested that the porcine IRF1 gene is strong candidate gene for these immune traits in pig.

Mouse (Murine) Interferon Regulatory Factor 1 (IRF1) interaction partners

  1. 5AZ had a protective effect after MI by potentiation of IRF1 sumoylation and is suggested as a novel therapeutic intervention for cardiac repair.

  2. direct the expression of a set of genes, the IRF8 (show IRF8 Antibodies)/IRF1 regulome, that play critical roles in host inflammatory and antimicrobial defenses in mouse models of neuroinflammation and of pulmonary tuberculosis, respectively

  3. couples synthesis of miR (show MLXIP Antibodies)-342-5p to the antiviral interferon (show IFNA Antibodies) response

  4. The gammaherpesvirus-driven germinal center expansion was exaggerated and lost its transient nature in the absence of interferon-regulatory factor 1 (IRF-1), a transcription factor with antiviral and tumor suppressor functions.

  5. IRF1 is required for IRF8 (show IRF8 Antibodies)-induced gene expression in microglia.

  6. in addition to regulating the enterocyte metabolic switch, Blimp1 functions as a gatekeeper in opposition to Irf1 to prevent premature activation of the MHC class I pathway in villus epithelium to maintain tolerance in the neonatal intestine.

  7. Although treatment with IFN-gamma (show IFNG Antibodies) strongly induced the activation of STAT1 (show STAT1 Antibodies) as a transcriptional activator, its target molecule, IRF1, was not clearly produced in Lmp2 (show PSMB9 Antibodies)-deficient uterine smooth muscle cells.

  8. found that the effect of PGC-1alpha (show PPARGC1A Antibodies) on repressing IRF-1 expression and activity is facilitated by the reduction in phosphorylation of STAT1 (show STAT1 Antibodies) at position 727 (S727P), an essential transcriptional activator of IRF-1

  9. translocates into the nucleus and acts on the 3'UTR (show UTS2R Antibodies) region of the IL-4 (show IL4 Antibodies) gene, thus inhibiting its transcription in Th2 cells during Listeria infection

  10. these results underline the role of Batf2/Irf1 in inducing inflammatory responses in M. tuberculosis infection.

IRF1 Antigen Profile

Antigen Summary

IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

Alternative names and synonyms associated with IRF1

  • interferon regulatory factor 1 (IRF1) antibody
  • interferon regulatory factor 1a (irf1a) antibody
  • interferon regulatory factor 1b (irf1b) antibody
  • interferon regulatory factor 1 (Irf1) antibody
  • AU020929 antibody
  • Irf-1 antibody
  • IRF1 antibody
  • irf11 antibody
  • MAR antibody
  • zgc:103566 antibody
  • zgc:136945 antibody

Protein level used designations for IRF1

interferon regulatory factor 1 , interferon regulatory factor 11 , IRF-1 , interferon responsive factor 1

443136 Ovis aries
678604 Danio rerio
792160 Danio rerio
396384 Gallus gallus
3659 Homo sapiens
481500 Canis lupus familiaris
396611 Sus scrofa
789216 Bos taurus
16362 Mus musculus
24508 Rattus norvegicus
100328724 Oryctolagus cuniculus
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