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anti-Human FOXA1 Antibodies:
anti-Mouse (Murine) FOXA1 Antibodies:
anti-Rat (Rattus) FOXA1 Antibodies:
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Human Monoclonal FOXA1 Primary Antibody for IHC (p), RNAi - ABIN561299
Bretschneider, Brand, Miller, Lowery, Kerin, Gannon, Denger: Estrogen induces repression of the breast cancer and salivary gland expression gene in an estrogen receptor alpha-dependent manner. in Cancer research 2008
Show all 4 Pubmed References
Human Monoclonal FOXA1 Primary Antibody for ChIPSeq, ChIP - ABIN2668682
Nucera, Eeckhoute, Finn, Carroll, Ligon, Priolo, Fadda, Toner, Sheils, Attard, Pontecorvi, Nose, Loda, Brown: FOXA1 is a potential oncogene in anaplastic thyroid carcinoma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2009
Show all 2 Pubmed References
Cow (Bovine) Polyclonal FOXA1 Primary Antibody for WB - ABIN2780597
Lupien, Eeckhoute, Meyer, Wang, Zhang, Li, Carroll, Liu, Brown: FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. in Cell 2008
Show all 2 Pubmed References
Human Polyclonal FOXA1 Primary Antibody for ChIP, IHC (p) - ABIN249930
Lin, Miller, Contreras, Prescott, Dagenais, Wu, Yee, Orringer, Misek, Hanash, Glover, Beer: The hepatocyte nuclear factor 3 alpha gene, HNF3alpha (FOXA1), on chromosome band 14q13 is amplified and overexpressed in esophageal and lung adenocarcinomas. in Cancer research 2002
FoxA1 discriminates between medullary thyroid carcinoma and tumors of follicular derivation with sensitivity and specificity greater than calcitonin (show CALCA Antibodies) and carcinoembryonic antigen (show CEACAM5 Antibodies).
FOXA1 loss may play a significant role in enabling prostate cancer progression to neuroendocrine prostate cancer, whereas IL-8 (show IL8 Antibodies) and MAPK/ERK (show MAPK1 Antibodies) pathways may be promising targets for therapeutic intervention.
Low FOXA1 expression is associated with breast cancer invasion and metastasis.
the distinct mechanisms by which GATA2 (show GATA2 Antibodies) and FOXA1 regulate AR cistrome and suggest that FOXA1 acts upstream of GATA2 (show GATA2 Antibodies) and AR in determining hormone-dependent gene expression in prostate cancer.
Study implicates enhancer reprogramming, FOXA1 upregulation, and a retrograde developmental transition in pancreatic ductal adenocarcinoma metastasis.
Studies indicate that microRNA miR (show MLXIP Antibodies)-212 exerts its inhibitory effect on hepatocellular carcinoma (HCC (show FAM126A Antibodies)) by inhibiting forkhead transcription factor FOXA1 expression.
FOXA1 is expressed by basal cells of squamous epithelium, pre-invasion lesions of the uterine cervix and the head/neck and almost half invasive cervical and head/neck carcinomas, supporting its possible implication in HPV associated carcinomas.
CREB1 (show CREB1 Antibodies)/FoxA1 signaling is a targetable driver of prostate cancer progression and serves as a biomarker of poor clinical outcomes.
miR (show MLXIP Antibodies)-93 may promote the process of epithelial-mesenchymal transition in endometrial carcinoma cells by targeting FOXA1.
conclusion, our results demonstrated that miR24 inhibits breast cancer cells invasion by targeting OGT (show OGT Antibodies) and reducing FOXA1 stability. These results also indicated that OGT (show OGT Antibodies) might be a potential target for the diagnosis and therapy of breast cancer metastasis.
this model system will facilitate further in vivo functional studies of Foxa1 or other factors in mammary gland development and tumor formation and progression
Loss of Interdependent Binding by the FoxO1 (show FOXO1 Antibodies) and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin (show INS Antibodies)-sensitive Genes.
FoxA1, FoxA2 (show FOXA2 Antibodies), and LIPG (show LIPG Antibodies) control the uptake of extracellular lipids for breast cancer growth.
genome-wide binding sites of the forkhead/winged helix transcription factor (show FOXP2 Antibodies) Foxa1, which functions redundantly with Foxa2 (show FOXA2 Antibodies) to regulate the differentiation of midbrain dopamine neurons, were characterized.
Disruption of Shp (show LAMC1 Antibodies) in mice alters timing of expression of genes that regulate homocysteine metabolism and the liver responses to ethanol and homocysteine. SHP (show LAMC1 Antibodies) inhibits the transcriptional activation of Bhmt (show BHMT Antibodies) and cystathionine gamma-lyase (show CTH Antibodies) by FOXA1.
ChIP-exonuclease of the ER pioneer factor FoxA1 identifies protected DNA with a predictable 8 bp overhang from the Forkhead motif, which authors term mesas; showed that mesas occur in multiple cellular contexts and exist as single or overlapping motifs.
TIP30 (show HTATIP2 Antibodies) is a key regulator for maintaining ER(+) and ER(-)luminal pools in the mammary luminal lineage via FoxA1.
Mechanistically, JARID1B (show KDM5B Antibodies) was required for GATA3 (show GATA3 Antibodies) recruitment to the Foxa1 promoter to activate Foxa1 expression.
Foxa1 recruited Grg3 to the Nanog (show NANOG Antibodies) promoter -2kb upstream region and switched the promoter to an inactive chromatin status represented by typical modifications in histone H3 (show HIST3H3 Antibodies).
Results indicate Foxa1 expression is required for the maintenance of prostatic cellular differentiation.
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.
forkhead box A1
, forkhead box protein A4
, HNF-3 alpha
, HNF3 alpha
, forkhead box protein A1
, forkhead transcription factor FoxA1
, forkhead homolog
, hepatocyte nuclear factor 3-alpha-like
, fork head domain protein 7
, hepatocyte nuclear factor 3-alpha
, HNF3alpha homolog B
, fork head domain-related protein 7'
, forkhead box protein A1-B
, forkhead protein 2
, hepatocyte nuclear factor 3-alpha homolog B
, transcription factor 3A
, hepatocyte nuclear factor 3 alpha
, fork head domain
, hepatocyte nuclear factor 3 alpha (winged helix transcription factor)
, hepatocyte nuclear factor 3, alpha