Recombinant HEK-293 Cells IgG isotype control (His tag)
-
- Target See all IgG products
- IgG
- Antibody Type
- Recombinant Antibody
- Fragment
- Fc fragment
- Reactivity
- Human
-
Host
- HEK-293 Cells
- Conjugate
- His tag
- Application
- Isotype Control (IsoC)
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27 kDa. The protein migrates as 34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Isotype
- IgG
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
- Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
- Storage
- -20 °C
-
- Target
- IgG
- Abstract
- IgG Products
- Target Type
- Antibody
- Background
- Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
- Molecular Weight
- 27 kDa
- UniProt
- P01857
-