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Browse our AGT Proteins (AGT)

Full name:
Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) Proteins (AGT)
On www.antibodies-online.com are 35 Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) Proteins from 14 different suppliers available. Additionally we are shipping AGT Antibodies (245) and AGT Kits (120) and many more products for this protein. A total of 446 AGT products are currently listed.
Synonyms:
Agat, AGT, AI265500, AI267024, Ang, AngI, AngII, ANGT, ANHU, ANRT, Aogen, PAT, Serpina8, Spat, SPT, wu:fb62f06, wu:fj87b02, zgc:111892
list all proteins Gene Name GeneID UniProt
AGT 24792 P09139
AGT 183 P01019
AGT 11606  

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AGT Proteins (AGT) by Origin

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Top referenced AGT Proteins

  1. Human AGT Protein expressed in HEK-293 Cells - ABIN2181742 : Goodfriend, Peach: Angiotensin III: (DES-Aspartic Acid-1)-Angiotensin II. Evidence and speculation for its role as an important agonist in the renin - angiotensin system. in Circulation research 1975 (PubMed)
    Show all 5 references for ABIN2181742

  2. Mouse (Murine) AGT Protein expressed in Human Cells - ABIN2007684 : Rice, Thomas, Grant, Turner, Hooper: Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. in The Biochemical journal 2004 (PubMed)
    Show all 2 references for ABIN2007684

More Proteins for AGT Interaction Partners

Zebrafish Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) interaction partners

Pig (Porcine) Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) interaction partners

Human Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) interaction partners

  1. NOXs had two time-dependent reactions in response to Ang II stimulation via MAPK (show MAPK1 Proteins) pathwa

  2. increased Ang-II/Ang-(1 (show ANGPT1 Proteins)-7) ratios may lead to Ang-II over-activation and aggravate atherosclerosis progression.

  3. urinary angiotensinogen could be a prognostic marker of the albuminuria reduction effects of olmesartan in patients with metabolic syndrome

  4. AGT (show AGXT Proteins) expression is significantly upregulated in human masticatory mucosa during wound healing

  5. Urinary angiotensinogen reflects intrarenal RAS status, and is of value to assess the severity of acute tubular necrosis .

  6. Data suggest that enhanced survival of normal prostate epithelial cells (PNT1A cell line) in presence of either or both angiotensin II (Ang II) and relaxin 2 (RLN2 (show RLN1 Proteins)) appears to be associated with increased ratio of BCL2 (show BCL2 Proteins)/BAX (show BAX Proteins) messenger RNA expression; thus, Ang II and/or RLN2 (show RLN1 Proteins) appear to be involved in regulation of apoptosis in prostate epithelium.

  7. increasing the serum levels of AngII increased the risk of acute myocardial infarction (AMI (show CFD Proteins)); the risk of AMI (show CFD Proteins) increased when the serum levels of AngII and KLK1 (show KLK1 Proteins) simultaneously increased; individuals with the combined genotypes of ACE (show ACE Proteins) DD and KLK1 (show KLK1 Proteins) GG showed increased risk of AMI (show CFD Proteins) compared with those with the combined genotypes of ACE (show ACE Proteins) II and KLK1 (show KLK1 Proteins) AA

  8. genetic association study and meta-analysis revealed a significant association between M235T polymorphism of angiotensinogen and myocardial infarction risk

  9. The aim of this work is to assess the influence of the rs1799752 polymorphism of the angiotensin-converting enzyme (ACE (show ACE Proteins)) gene and the rs699 polymorphism of the angiotensinogen (AGT) gene on the in-stent restenosis in Polish patients with stable coronary artery disease.

  10. in cultured H9C2 cells and that CyPA (show PPIA Proteins)/CD147 (show BSG Proteins) signaling pathway inhibition protects against Ang II-induced cardiomyocyte hypertrophy.

Mouse (Murine) Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) interaction partners

  1. the beneficial actions of insulin (show INS Proteins) in diabetic nephropathy appear to be mediated, in part, by suppressing renal Nrf2 (show NFE2L2 Proteins) and Agt (show AGXT Proteins) gene transcription and preventing Nrf2 (show NFE2L2 Proteins) stimulation of Agt (show AGXT Proteins) expression via hnRNP F (show HNRNPF Proteins)/K.

  2. Angiotensinogen-mediated downregulation of aquaporin 1 (show AQP1 Proteins) and Nrf2 (show NFE2L2 Proteins) signalling may play an important role in intrarenal renin (show REN Proteins)-angiotensin system-induced hypertension and kidney injury.

  3. This study suggests that deletion of AT2R decreases the expression of the beneficial ACE2/Ang-(1-7)/MasR.

  4. an inverse correlation was found between Ang-(1 (show ANGPT1 Proteins)-7) level and tau hyperphosphorylation, a pathological hallmark of Alzheimer's disease, in cerebral cortex and hippocampus of SAMP8 mice.

  5. The inhibition of pathological autophagy in the heart in response to chronic Ang II by Interleukin-10 (show IL10 Proteins), and its implications, has been described.

  6. These results suggest that increased formation of AT1R (show AGTRAP Proteins)-P2Y6R (show P2RY6 Proteins) heterodimers with age may increase the likelihood of hypertension induced by Ang II.

  7. These data suggest dysregulation of renin (show REN Proteins)-angiotensin system in acute pancreatitis as evidenced by altered Ang II/Ang-(1 (show ANGPT1 Proteins)-7) levels induced by the imbalance of ACE (show ACE Proteins)/ACE2 (show ACE2 Proteins) activity.

  8. Results indicate that Ang III produces nociceptive behavior similar to Ang II, and suggest that the phosphorylation of p38 MAPK (show MAPK14 Proteins) mediated through AT1 (show SLC33A1 Proteins) receptors on spinal astrocytes and neurons contributes to Ang II- and III-induced nociceptive behavior

  9. SIRT1 (show SIRT1 Proteins) and the axis AII (show ARG2 Proteins)/AT1 (show SLC33A1 Proteins)/NADPH-oxidase (show NOX1 Proteins) regulate each other

  10. Angiotensin (1-7) and Bradykinin may have roles in diabetic nephropathy induced by increased ACE (show ACE Proteins) gene dosage

Cow (Bovine) Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) interaction partners

  1. The metabolism of angiotensin II (Ang II) to angiotensin III (Ang III) and its role in the vasorelaxation response in adrenal arteries are reported.

  2. The study identified the serine phosphorylation (p-Ser (show SIGLEC1 Proteins)) sites induced by PKC-Beta (show PRKCB Proteins) activation or AGT, which inhibits insulin (show INS Proteins)-induced p-Tyr (show TYR Proteins) sites on IRS2 (show IRS2 Proteins) and its signals in endothelial cells.

  3. Data suggest up-regulation of AGT in granulosa cells and of Ang II in follicular fluid during preovulatory period; Ang II appears to amplify stimulatory effects of luteinizing hormone on secretion of progesterone/prostaglandins by granulosa cells.

  4. Data suggest that angiotensin II promotes uptake/accumulation of iron (non-transferrin (show Tf Proteins) bound iron) into vascular endothelial cells; such iron accumulation appears to depend on activation of angiotensin type 1 receptor and promotes oxidative stress.

  5. a critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically dependent on MARCKS, Rac1, and c-Abl.

  6. The objective of this study was to characterize the profiles of Ang-(1-7), MAS receptor, ACE(2), NEP and PEP during the ovulatory process in cattle.

  7. Fetal adrenal cells in primary culture respond to angiotensin-II by increasing aldosterone production and aldosterone synthase (show CYP11B2 Proteins) [P450c18/CYP11B2 (show CYP11B2 Proteins)] activity.

  8. ANG II inhibits bTREK-1 K(+) channels by a Ca(2+)-dependent mechanism that does not require the depletion of membrane-associated PIP(2).

  9. prostaglandin F2alpha, endothelin-1 (show EDN1 Proteins), and angiotensin II may interact with each other in a local positive feedback manner to activate their secretion in the regressing corpus luteum, thus accelerating and completing luteolysis

  10. Suggest that the activation of a local positive feedback mechanism in the corpus luteum among ET-1 (show EDN1 Proteins), Ang II and PGF2alpha might play a functional role in the paracrine modulation of luteolytic cascade.

AGT Protein Profile

Protein Summary

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Alternative names and synonyms associated with AGT

  • angiotensinogen (agt)
  • angiotensinogen (AGT)
  • Angiotensinogen (angt)
  • alanine-glyoxylate aminotransferase (Agxt)
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT)
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (Agt)
  • angiotensinogen-like (LOC100157073)
  • angiotensinogen-like (LOC100065526)
  • O-6-methylguanine-DNA methyltransferase (Mgmt)
  • Agat protein
  • AGT protein
  • AI265500 protein
  • AI267024 protein
  • Ang protein
  • AngI protein
  • AngII protein
  • ANGT protein
  • ANHU protein
  • ANRT protein
  • Aogen protein
  • PAT protein
  • Serpina8 protein
  • Spat protein
  • SPT protein
  • wu:fb62f06 protein
  • wu:fj87b02 protein
  • zgc:111892 protein

Protein level used designations for AGT

zC8A9.1 (angiotensinogen ) , angiotensinogen , serpin peptidase inhibitor, clade A, member 8 , Angiotensinogen , alanine--glyoxylate aminotransferase , angiotensin receptor 2 , serine--pyruvate aminotransferase, mitochondrial , serine--pyruvate aminotransferase, peroxisomal , serine-pyruvate aminotransferase , serine:pyruvate aminotransferase SPT , serine:pyruvate/alanine:glyoxylate aminotransferase , alpha-1 antiproteinase, antitrypsin , angiotensin I , angiotensin II , pre-angiotensinogen , serine (or cysteine) proteinase inhibitor , serpin A8 , angiotensin ll , angiotensinogen (PAT) , Serpin A8 , 6-O-methylguanine-DNA methyltransferase , O-6-alkylguanine-DNA alkyltransferase , O-6-methylguanine-DNA-alkyltransferase , methylated-DNA--protein-cysteine methyltransferase

GENE ID SPECIES
322485 Danio rerio
714203 Macaca mulatta
100127472 Sus scrofa
100195417 Salmo salar
24792 Rattus norvegicus
183 Homo sapiens
11606 Mus musculus
24179 Rattus norvegicus
403783 Canis lupus familiaris
100724950 Cavia porcellus
527114 Bos taurus
421543 Gallus gallus
100294599 Ovis aries
101119440 Ovis aries
450104 Pan troglodytes
100389395 Callithrix jacchus
100157073 Sus scrofa
100065526 Equus caballus
17314 Mus musculus
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