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Browse our AGT Proteins (AGT)

Full name:
Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) Proteins (AGT)
On are 27 Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) Proteins from 12 different suppliers available. Additionally we are shipping AGT Antibodies (202) and AGT Kits (120) and many more products for this protein. A total of 383 AGT products are currently listed.
Agat, AGT, AI265500, AI267024, Ang, AngI, AngII, ANGT, ANHU, ANRT, Aogen, PAT, Serpina8, Spat, SPT, wu:fb62f06, wu:fj87b02, zgc:111892
list all proteins Gene Name GeneID UniProt
AGT 24792 P09139
AGT 183 P01019
AGT 11606  

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AGT Proteins (AGT) by Origin

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Top referenced AGT Proteins

  1. Human AGT Protein expressed in HEK-293 Cells - ABIN2181742 : Goodfriend, Peach: Angiotensin III: (DES-Aspartic Acid-1)-Angiotensin II. Evidence and speculation for its role as an important agonist in the renin - angiotensin system. in Circulation research 1975 (PubMed)
    Show all 5 references for ABIN2181742

  2. Mouse (Murine) AGT Protein expressed in Human Cells - ABIN2007684 : Rice, Thomas, Grant, Turner, Hooper: Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. in The Biochemical journal 2004 (PubMed)
    Show all 2 references for ABIN2007684

More Proteins for AGT Interaction Partners

Zebrafish Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) interaction partners

Pig (Porcine) Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) interaction partners

Human Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) interaction partners

  1. rs699 in the AGT gene and rs5186 in the ATR1 gene were not associated with the risk and clinical outcomes of IgAN.

  2. The threonine variant of AGT (show AGXT Proteins) M268T is a significant risk factor for abnormalities in specific white matter tracts and cognitive domains in healthy older adults.

  3. Increased plasma renin, AT and VEGF might play a role in the onset or development of superficial infantile hemangiomas.

  4. Blood pressure was significantly lower in angiotensinogen knock-out mice compared to controls fed a normal or high sodium diet.

  5. Detection of hANG(1-12) in hearts of homozygous transgenic rats expressing the hAGT gene suggests existence of non-renin (show REN Proteins)-dependent enzyme mechanism capable of cleavage of human substrate.

  6. AGT (show AGXT Proteins)-H1 haplotype was identified as protective Factor for Essential Hypertension in Kazakhs in Xinjiang.

  7. dominance of the aminopeptidase A (show ENPEP Proteins)/Ang (2 (show ANGPT2 Proteins)-10) and aminopeptidase A (show ENPEP Proteins)/Ang III (2-8) pathways in the metabolism of Ang I (1-10) and Ang II (1-8) over the ACE2 (show ACE2 Proteins)/Ang (1 (show ANGPT1 Proteins)-7) axis

  8. The ACE2 (show ACE2 Proteins)-Ang (1 (show ANGPT1 Proteins)-7)-Mas (show MAS1 Proteins) axis serves as an important signal pathway in endothelial cell protection in diabetic human arteries.

  9. Urinary AGT (show AGXT Proteins) could be a prognostic marker of renoprotective effects of alogliptin in patients with T2D

  10. urinary AGT (show AGXT Proteins)/protein ratio represents a novel specific marker of podocyte injury

Mouse (Murine) Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) interaction partners

  1. Results indicate that Ang III produces nociceptive behavior similar to Ang II, and suggest that the phosphorylation of p38 MAPK (show MAPK14 Proteins) mediated through AT1 (show SLC33A1 Proteins) receptors on spinal astrocytes and neurons contributes to Ang II- and III-induced nociceptive behavior

  2. SIRT1 (show SIRT1 Proteins) and the axis AII (show ARG2 Proteins)/AT1 (show SLC33A1 Proteins)/NADPH-oxidase (show NOX1 Proteins) regulate each other

  3. Angiotensin (1-7) and Bradykinin may have roles in diabetic nephropathy induced by increased ACE (show ACE Proteins) gene dosage

  4. MAS (show MAS1 Proteins) receptors mediate vasoprotective and atheroprotective effects of candesartan upon the recovery of vascular angiotensin-converting enzyme 2 (show ACE2 Proteins)-angiotensin-(1-7)-MAS (show MAS1 Proteins) axis functionality

  5. AGT (show AGXT Proteins) contributes to body weight gain and liver steatosis through functions of the des (show DES Proteins)(angiotensin I)AGT domain, which are independent of angiotensin II production.

  6. the augmented AGT (show AGXT Proteins) released from apoptotic endothelial cells acts as a vital progenitor of Ang II to accelerate vascular remodelling

  7. Humid heat stress increased oxidative stress and caused apoptosis of cardiomyocytes through the Ang II signaling pathway.

  8. ACE2 (show ACE2 Proteins) and Ang-(1 (show ANGPT1 Proteins)-7) significantly inhibit early atherosclerotic lesion formation via protection of endothelial function and inhibition of inflammatory response.

  9. This study demonstrates for the first time a non-linear dose-response for alkylation-induced colorectal carcinogenesis and reveals DNA repair by MGMT (show MGMT Proteins), but not AAG (show C16orf35 Proteins), as a key node in determining a carcinogenic threshold.

  10. reductions in plasma angiotensin concentrations in obese hepatocyte AGT (show AGXT Proteins)-deficient mice may have limited megalin (show LRP2 Proteins)-dependent uptake of AGT (show AGXT Proteins) into adipocytes for the production of Ang II in the development of obesity-hypertension.

Cow (Bovine) Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) interaction partners

  1. The metabolism of angiotensin II (Ang II) to angiotensin III (Ang III) and its role in the vasorelaxation response in adrenal arteries are reported.

  2. The study identified the serine phosphorylation (p-Ser (show SIGLEC1 Proteins)) sites induced by PKC-Beta (show PRKCB Proteins) activation or AGT, which inhibits insulin (show INS Proteins)-induced p-Tyr (show TYR Proteins) sites on IRS2 (show IRS2 Proteins) and its signals in endothelial cells.

  3. Data suggest up-regulation of AGT in granulosa cells and of Ang II in follicular fluid during preovulatory period; Ang II appears to amplify stimulatory effects of luteinizing hormone on secretion of progesterone/prostaglandins by granulosa cells.

  4. Data suggest that angiotensin II promotes uptake/accumulation of iron (non-transferrin (show Tf Proteins) bound iron) into vascular endothelial cells; such iron accumulation appears to depend on activation of angiotensin type 1 receptor and promotes oxidative stress.

  5. a critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically dependent on MARCKS, Rac1, and c-Abl.

  6. The objective of this study was to characterize the profiles of Ang-(1-7), MAS receptor, ACE(2), NEP and PEP during the ovulatory process in cattle.

  7. Fetal adrenal cells in primary culture respond to angiotensin-II by increasing aldosterone production and aldosterone synthase (show CYP11B2 Proteins) [P450c18/CYP11B2 (show CYP11B2 Proteins)] activity.

  8. ANG II inhibits bTREK-1 K(+) channels by a Ca(2+)-dependent mechanism that does not require the depletion of membrane-associated PIP(2).

  9. prostaglandin F2alpha, endothelin-1 (show EDN1 Proteins), and angiotensin II may interact with each other in a local positive feedback manner to activate their secretion in the regressing corpus luteum, thus accelerating and completing luteolysis

  10. Suggest that the activation of a local positive feedback mechanism in the corpus luteum among ET-1 (show EDN1 Proteins), Ang II and PGF2alpha might play a functional role in the paracrine modulation of luteolytic cascade.

AGT Protein Profile

Protein Summary

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Alternative names and synonyms associated with AGT

  • angiotensinogen (agt)
  • angiotensinogen (AGT)
  • Angiotensinogen (angt)
  • alanine-glyoxylate aminotransferase (Agxt)
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT)
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (Agt)
  • angiotensinogen-like (LOC100157073)
  • angiotensinogen-like (LOC100065526)
  • O-6-methylguanine-DNA methyltransferase (Mgmt)
  • Agat protein
  • AGT protein
  • AI265500 protein
  • AI267024 protein
  • Ang protein
  • AngI protein
  • AngII protein
  • ANGT protein
  • ANHU protein
  • ANRT protein
  • Aogen protein
  • PAT protein
  • Serpina8 protein
  • Spat protein
  • SPT protein
  • wu:fb62f06 protein
  • wu:fj87b02 protein
  • zgc:111892 protein

Protein level used designations for AGT

zC8A9.1 (angiotensinogen ) , angiotensinogen , serpin peptidase inhibitor, clade A, member 8 , Angiotensinogen , alanine--glyoxylate aminotransferase , angiotensin receptor 2 , serine--pyruvate aminotransferase, mitochondrial , serine--pyruvate aminotransferase, peroxisomal , serine-pyruvate aminotransferase , serine:pyruvate aminotransferase SPT , serine:pyruvate/alanine:glyoxylate aminotransferase , alpha-1 antiproteinase, antitrypsin , angiotensin I , angiotensin II , pre-angiotensinogen , serine (or cysteine) proteinase inhibitor , serpin A8 , angiotensin ll , angiotensinogen (PAT) , Serpin A8 , 6-O-methylguanine-DNA methyltransferase , O-6-alkylguanine-DNA alkyltransferase , O-6-methylguanine-DNA-alkyltransferase , methylated-DNA--protein-cysteine methyltransferase

322485 Danio rerio
714203 Macaca mulatta
100127472 Sus scrofa
100195417 Salmo salar
24792 Rattus norvegicus
183 Homo sapiens
11606 Mus musculus
24179 Rattus norvegicus
403783 Canis lupus familiaris
100724950 Cavia porcellus
527114 Bos taurus
421543 Gallus gallus
100294599 Ovis aries
101119440 Ovis aries
450104 Pan troglodytes
100389395 Callithrix jacchus
100157073 Sus scrofa
100065526 Equus caballus
17314 Mus musculus
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