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anti-Human FYN antibody for Immunohistochemistry (Frozen Sections)

Recommended FYN Antibody (supplied by: Log in to see )

Antigen
FYN Oncogene Related To SRC, FGR, YES (FYN) Antibodies
  • AI448320
  • AW552119
  • c-fyn
  • cfyn-a
  • fyn
  • im:6908851
  • p59-FYN
  • PKC
  • si:dkey-119m7.5
  • SLK
  • SYN
  • zgc:86720
  • zgc:109996
Epitope
AA 7-176
56
20
20
15
14
8
5
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
184
89
37
7
7
7
2
1
1
1
1
Host
Mouse
128
64
16
Clonality
Monoclonal
Conjugate
This FYN antibody is un-conjugated
8
7
7
7
7
7
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
188
112
49
24
24
18
14
12
5
4
2
2
2
2
1
Supplier
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Catalog No. ABIN206566
$ 463.83
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088050903 ABIN2473714 IHC (fro) IP WB Mouse IgG2b AA 7-176 Log in to see FYN-01 4
0.00088050903 ABIN201639 IHC (fro) IP ELISA WB Mouse IgG1 AA 1-206 Log in to see
0.00088050903 ABIN1868071 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
0.00088050903 ABIN644808 IHC (fro) IP WB Mouse Log in to see

Top referenced anti-FYN antibody for Immunohistochemistry (Frozen Sections)

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Flow Cytometry (FACS) 18 Antibodies
Functional Studies (Func) 1 Antibodies
Immunochromatography (IC) 2 Antibodies
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Immunofluorescence (IF) 14 Antibodies
Immunohistochemistry (IHC) 50 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
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Proximity Ligation Assay (PLA) 2 Antibodies
Western Blotting (WB) 175 Antibodies

General

Antigen FYN Oncogene Related To SRC, FGR, YES (FYN) Antibodies
Epitope AA 7-176
(56), (20), (20), (15), (14), (8), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(184), (89), (37), (7), (7), (7), (2), (1), (1), (1), (1)
Host Mouse
(128), (64), (16)
Clonality
Monoclonal
Conjugate This FYN antibody is un-conjugated
(8), (7), (7), (7), (7), (7)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
(188), (112), (49), (24), (24), (18), (14), (12), (5), (4), (2), (2), (2), (2), (1)
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Product Details anti-FYN Antibody

Target Details FYN Application Details Handling Images
Specificity Recognizes p59fyn (fyn), a 59kD member of the src family of non receptor protein tyrosine kinases, expressed by T cells and Natural Killer (NK) cells and highly expressed in brain. Fyn plays a vital role in thymocyte development and T cell activation and is essential for TCR-mediated signal transduction through association with the T Cell Receptor (TCR) eta chain/CD3 Complex. This association, results in protein kinase activation and the subsequent protein tyrosine phosphorylation of multiple immunoreceptor tyrosine-based activation motifs (ITAMs), which triggers the phosphorylation of further substrates downstream in the T cell signaling cascade. Recent studies into Alzheimer's Disease have implicated fyn in neurodegeneration, through the tyrosine phosphorylation of the microtubule-associated protein tau, a prominent component of neurofibrillary tangles. *Detects a band of approximately 59kD in Mouse EL-4 cell lysates in Western Blot.
Cross-Reactivity Mouse (Murine)
Purification Protein A Column
Immunogen Bacterially expressed recombinant fragment of human Fyn aa 7-176.
Isotype IgG

Target Details FYN

Product Details anti-FYN Antibody Application Details Handling Images back to top
Antigen
Alternative Name SYN / FYN (FYN Antibody Abstract)
Background Standard Gene Symbol: FYN, Gene Family: Protein Kinase, Gene Subfamily: Src, Synonyms: FYN, C-syn protooncogene, Fyn kinase, Fyn tyrosine kinase, p59-FYN, SYN, Src-like kinase, Src/yes-related novel, Tyrosine kinase fyn, Tyrosine kinase p59fyn(T), Tyrosine-protein kinase Fyn, Proto-oncogene c-Fyn, Proto-oncogene Syn
Gene ID 2534
UniProt P06241
Pathways JAK-STAT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-FYN Antibody Target Details FYN Handling Images back to top
Application Notes IHC-Fr, IP, WB
Restrictions For Research Use only

Handling

Product Details anti-FYN Antibody Target Details FYN Application Details Images back to top
Concentration 1 mg/mL
Buffer PBS, pH 7.4, 0.09% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.