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anti-Rat (Rattus) FYN antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FYN Antibody (supplied by: Log in to see )

Antigen
FYN Oncogene Related To SRC, FGR, YES (FYN) Antibodies
  • AI448320
  • AW552119
  • c-fyn
  • cfyn-a
  • fyn
  • im:6908851
  • p59-FYN
  • PKC
  • si:dkey-119m7.5
  • SLK
  • SYN
  • zgc:86720
  • zgc:109996
Epitope
pTyr530
56
20
19
15
15
8
5
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
184
88
36
7
7
7
2
1
1
1
1
Host
Rabbit
127
65
16
Clonality
Polyclonal
Conjugate
This FYN antibody is un-conjugated
8
7
7
7
7
7
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
189
112
49
25
23
18
14
12
6
4
2
2
2
2
1
Supplier
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Catalog No. ABIN498840
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089488085 ABIN264422 IHC (p) WB Mouse IgG1 AA 1-206, AA 26-75, N-Term Log in to see 1S 2

Top referenced anti-FYN antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-FYN Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 175 Antibodies 77 Antibodies 32 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Immunoprecipitation (IP) 27 Antibodies 12 Antibodies 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 22 Antibodies 15 Antibodies 2 Antibodies
Immunohistochemistry (IHC) 50 Antibodies 19 Antibodies 11 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 5 Antibodies 3 Antibodies 1 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies

General

Antigen FYN Oncogene Related To SRC, FGR, YES (FYN) Antibodies
Epitope pTyr530
(56), (20), (19), (15), (15), (8), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(184), (88), (36), (7), (7), (7), (2), (1), (1), (1), (1)
Host Rabbit
(127), (65), (16)
Clonality
Polyclonal
Conjugate This FYN antibody is un-conjugated
(8), (7), (7), (7), (7), (7)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(189), (112), (49), (25), (23), (18), (14), (12), (6), (4), (2), (2), (2), (2), (1)
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Product Details anti-FYN Antibody

Target Details FYN Application Details Handling Images
Specificity This antibody detects endogenous levels of p-Fyn protein.
Purification Affinity Chromatography using epitope-specific immunogen.

Target Details FYN

Product Details anti-FYN Antibody Application Details Handling Images back to top
Antigen
Alternative Name FYN (FYN Antibody Abstract)
Background Fyn is a membrane-associated, non-receptor protein tyrosine kinase approximately 59 kDa, which belongs to the Src family of cytoplasmic tyrosine kinases. Fyn is very strongly similar to mouse Fyn, v-yes and c-src. Fyn is expressed predominately in tissues of neuronal and hematopoietic origin. Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing. Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation. In T cells, Fyn associates with the T-cell antigen receptor and Thy1.The unique N terminal domain of Fyn interacts with the CD3 and eta chains of the TcR. Fyn can bind to other proteins (p82 and p116) through its SH2 and SH3 domains, which may act as substrates or regulators of Fyn activity. Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation.Synonyms: Proto-oncogene tyrosine-protein kinase Fyn, Protooncogene Syn, SLK, p59-Fyn
Molecular Weight approx. 59 kDa
Gene ID 2534
NCBI Accession NP_002028
UniProt P06241
Pathways JAK-STAT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-FYN Antibody Target Details FYN Handling Images back to top
Application Notes Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-FYN Antibody Target Details FYN Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-FYN Antibody Target Details FYN Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (pTyr530) (ABIN498840) Immunohistochemistry analysis of Fyn antibody pTyr530 in paraffin-embedded Hum...