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|Antigen||Interferon, beta 1, Fibroblast (IFNB1) Antibodies|
|Conjugate||This IFNB1 antibody is un-conjugated Alternatives|
Neutralization (Neut), ELISA, Western Blotting (WB)
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Product Details anti-IFNB1 AntibodyTarget Details IFNB1 Application Details Handling Images
Affinity purified Goat polyclonal IFN beta antibody
Bioactivity: The exact concentration of antibody required to neutralize human interferon beta activity is dependent on the cytokine concentration, cell type, growth conditions and type of activity studied. The Neutralization Dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. The ND50 for this antibody on human (HeLa/EMCV) cells is approx. 0.05- 0.2 µg/mL in the presence of 10ng/mL of human interferon beta, based on the anti-viral assay. The specific conditions are described in the figure legends.
|Immunogen||IFN beta antibody was raised in goat using human interferon beta as the immunogen.|
Target Details IFNB1Product Details anti-IFNB1 Antibody Application Details Handling Images back to top
|Alternative Name||IFN beta (IFNB1 Antibody Abstract)|
|Background||Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens-such as viruses, bacteria, or parasites-or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.|
|Research Area||Cytokines, Immunology|
|Pathways||JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy|
Application DetailsProduct Details anti-IFNB1 Antibody Target Details IFNB1 Handling Images back to top
|Application Notes||Optimal conditions should be determined byt he investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-IFNB1 Antibody Target Details IFNB1 Application Details Images back to top
|Reconstitution||Reconstitute in sterile PBS.|
|Buffer||Lyophilized from PBS with 5 % trehalose.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Aliquot and store at -20 °C.|