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anti-Human IFNB1 antibody for Neutralization

Recommended IFNB1 Antibody (supplied by: Log in to see )

Antigen
Interferon, beta 1, Fibroblast (IFNB1) Antibodies
  • IFB
  • Ifb
  • IFF
  • IFN-beta
  • IFN-R
  • IFN-R-2
  • IFNb
  • IFNB
  • Ifnb
  • IFNBR
Reactivity
Human
301
30
15
15
11
7
7
5
5
3
1
1
1
Host
Mouse
190
159
9
6
6
4
4
Clonality
Monoclonal
Conjugate
This IFNB1 antibody is un-conjugated
32
27
14
8
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
1
1
1
1
1
1
1
Application
Neutralization (Neut)
306
263
84
48
32
26
24
23
15
14
12
8
7
5
4
2
2
2
1
1
Supplier
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Catalog No. ABIN335675
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008657434 ABIN298986 Neut Sheep IgG Log in to see Polyclonal
0.0008657434 ABIN289463 Neut ELISA WB Goat IgG Log in to see Polyclonal
0.0008657434 ABIN352084 Neut ELISA WB Goat Log in to see Polyclonal
0.0008657434 ABIN2296840 Neut Sheep IgG Log in to see Polyclonal
0.0008657434 ABIN2288112 Neut IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0008657434 ABIN2288132 Neut IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG Log in to see Polyclonal
0.0008657434 ABIN2288135 Neut IHC ELISA WB APC Rabbit IgG Log in to see Polyclonal
0.0008657434 ABIN2288137 Neut IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
0.0008657434 ABIN2288139 Neut IHC ELISA WB FITC Rabbit IgG Log in to see Polyclonal
0.0008657434 ABIN2288141 Neut IHC ELISA WB HRP Rabbit IgG Log in to see Polyclonal
0.0008657434 ABIN2288143 Neut IHC ELISA WB PE Rabbit IgG Log in to see Polyclonal

Top referenced anti-IFNB1 antibody for Neutralization

Similar anti-IFNB1 Antibodies

Application / Reactivity Human
Blocking Antibody (Inhibition) 1 Antibodies
ELISA 213 Antibodies
ELISA (Capture) 2 Antibodies
ELISA (Detection) 2 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 23 Antibodies
Functional Studies (Func) 17 Antibodies
Immunoassay (IA) 4 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 71 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 11 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 21 Antibodies
Immunoprecipitation (IP) 35 Antibodies
Neutralization (Neut) 12 Antibodies
Western Blotting (WB) 256 Antibodies

General

Antigen Interferon, beta 1, Fibroblast (IFNB1) Antibodies
Reactivity Human
(301), (30), (15), (15), (11), (7), (7), (5), (5), (3), (1), (1), (1)
Host Mouse
(190), (159), (9), (6), (6), (4), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IFNB1 antibody is un-conjugated
(32), (27), (14), (8), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1)
Application Neutralization (Neut)
(306), (263), (84), (48), (32), (26), (24), (23), (15), (14), (12), (8), (7), (5), (4), (2), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-IFNB1 Antibody

Target Details IFNB1 Application Details Handling References for anti-IFNB1 Antibody (ABIN335675) Images
Specificity The A1 monoclonal antibody reacts with human IFN-β. The A1 antibody is a neutralizing antibody. IFN-β is classified as a type I IFN which is a group of structurally and functionally related proteins demonstrating anti-viral, anti-parasitic, and anti-proliferative activities.
Cross-Reactivity (Details) The A1 monoclonal antibody reacts with human IFN-beta.
Characteristics The A1 monoclonal antibody reacts with human IFN-β. The A1 antibody is a neutralizing antibody. IFN-β is classified as a type I IFN which is a group of structurally and functionally related proteins demonstrating anti-viral, anti-parasitic, and anti-proliferative activities.
Synonyms: Synonyms: IFNb, IFN-b, Interferon-beta
Purification Affinity Purified
Endotoxin Level <0.001 ng endotoxin/μg
Grade Functional Grade
Clone A1 (IFNb)
Isotype IgG1 kappa

Target Details IFNB1

Product Details anti-IFNB1 Antibody Application Details Handling References for anti-IFNB1 Antibody (ABIN335675) Images back to top
Antigen
Alternative Name IFN-B (IFNB1 Antibody Abstract)
Background The A1 antibody is a neutralizing antibody. IFN-beta is classified as a type I IFN which is a group of structurally and functionally related proteins demonstrating anti-viral, anti-parasitic, and anti-proliferative activities.
Research Area Cytokines
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IFNB1 Antibody Target Details IFNB1 Handling References for anti-IFNB1 Antibody (ABIN335675) Images back to top
Application Notes Applications reported: The A1 antibody has been reported for use in cytokine neutralization.

Applications tested: The Functional Grade Purified A1 antibody has been tested in bioassay for neutralization of IFN-beta bioactivity. The A1 antibody at 3-6 μg/mL has been found to inhibit by 50 % the biological effects of 50 pg/mL human IFN-beta (ND50), in an EMCV assay of A549 cell protection. Detailed information and protocols about cytokine bioassays and in vitro cytokine neutralization using antibodies can be found in the Best Protocols® section.
Restrictions For Research Use only

Handling

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details References for anti-IFNB1 Antibody (ABIN335675) Images back to top
Concentration 1 mg/mL
Buffer aqueous buffer, no sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Use in sterile environment.
Storage 4 °C

References for anti-IFNB1 Antibody (ABIN335675)

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details Handling Images back to top
Background publications

Shepard, Leung, Stebbing, Goeddel: "A single amino acid change in IFN-beta1 abolishes its antiviral activity." in: Nature, Vol. 294, Issue 5841, pp. 563-5, 1982