IFNB1 antibody (Center)

Catalog No. ABIN499962

Cited in 2+ publications. The Rabbit Polyclonal anti-IFNB1 antibody (ABIN499962) specifically detects IFNB1 in WB, IHC (p) and EIA. The antibody is reactive with Human and Mouse samples.

Quick Overview for IFNB1 antibody (Center) (ABIN499962)

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-IFNB1 Antibody

Binding Specificity: Center

Specificity: This antibody reacts to IFN-beta.

Purification: Affinity chromatography purified via peptide column

Immunogen: IFN-beta antibody was raised against a 17 amino acid peptide from near the center of human IFN-b.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: approx. 5 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

References for anti-IFNB1 antibody (ABIN499962)

Chen, Jie, Tang, Meng, Li, Li, Chen, Yan, Kurihara, Li, He: "New insights into the effects and mechanism of a classic traditional Chinese medicinal formula on influenza prevention." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 27, pp. 52-62, (2017) (PubMed).

Jie, Luo, Chen, Wang, Yan, Mao, Xiao, Kurihara, Li, He: "Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling." in: Oncotarget, Vol. 8, Issue 62, pp. 105615-105629, (2017) (PubMed).

Target Details for IFNB1

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Alternative Name: IFNB / Interferon beta

Background: Type I Interferons (IFN-a/b) are produced primarily in response to viral infection by Synonyms: Fibroblast interferon, IFB, IFN-beta, IFNB1

Gene ID: 3456

NCBI Accession: NP_002167

UniProt: P01574

Pathways: JAK-STAT Signaling, TCR Signaling, TLR Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome