You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mouse (Murine) IFNB1 antibody for Immunoprecipitation

Recommended IFNB1 Antibody (supplied by: Log in to see )

Antigen
Interferon, beta 1, Fibroblast (IFNB1) Antibodies
  • IFB
  • Ifb
  • IFF
  • IFN-beta
  • IFN-R
  • IFN-R-2
  • IFNb
  • IFNB
  • Ifnb
  • IFNBR
Reactivity
Mouse (Murine)
306
29
15
15
11
7
7
5
5
3
1
1
1
Host
Hamster
192
161
10
6
6
4
3
Clonality
Monoclonal
Conjugate
This IFNB1 antibody is un-conjugated
32
27
14
8
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
1
1
1
1
1
1
1
Application
Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
307
267
83
48
32
26
25
24
17
14
12
8
7
5
4
2
2
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN2665064
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089556724 ABIN2665499 FACS IF IP IHC WB Goat Ig Fraction Log in to see Polyclonal 2
0.00089556724 ABIN636538 IP IHC ELISA WB Rabbit Log in to see Polyclonal 1
0.00089556724 ABIN1830029 IP Neut IHC ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
0.00089556724 ABIN1830371 IP Neut IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.00089556724 ABIN2296877 IP Neut IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.00089556724 ABIN189844 Func IHC (fro) IP ELISA WB Rabbit Log in to see Polyclonal

Top referenced anti-IFNB1 antibody for Immunoprecipitation

Similar anti-IFNB1 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 15 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 3 Antibodies
Functional Studies (Func) 2 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 13 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Multiplex Assay (MA) 2 Antibodies
Neutralization (Neut) 3 Antibodies
Western Blotting (WB) 21 Antibodies

General

Antigen Interferon, beta 1, Fibroblast (IFNB1) Antibodies
Reactivity Mouse (Murine)
(306), (29), (15), (15), (11), (7), (7), (5), (5), (3), (1), (1), (1)
Host Hamster
(192), (161), (10), (6), (6), (4), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IFNB1 antibody is un-conjugated
(32), (27), (14), (8), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1)
Application Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(307), (267), (83), (48), (32), (26), (25), (24), (17), (14), (12), (8), (7), (5), (4), (2), (2), (2), (1), (1)
Pubmed 5 references available
Supplier Log in to see

Product Details anti-IFNB1 Antibody

Target Details IFNB1 Application Details Handling References for anti-IFNB1 Antibody (ABIN2665064) Images
Purification The antibody was purified by affinity chromatography.
Clone MIB-5E9-1
Isotype IgG

Target Details IFNB1

Product Details anti-IFNB1 Antibody Application Details Handling References for anti-IFNB1 Antibody (ABIN2665064) Images back to top
Antigen
Alternative Name IFN-beta (IFNB1 Antibody Abstract)
Background Interferon-β is a member of the type I interferon class. Type I IFNs are involved in the innate immune system, being released non-specifically during the early stage of infection in response to stimuli such as viruses, dsRNA, LPS, and bacterial components. Once secreted by virus-infected or activated cells, they bind to the IFNα/β receptor (IFNAR), which is found on almost all cell types, and, via the JAK-STAT pathway, induce the expression of hundreds of IFN-stimulated genes (ISGs). While the function of many of these proteins remains to be elucidated, a hallmark of type I IFNs is their anti-viral activities, both general and specific against particular viruses. Type I IFNs also regulate cell growth and apoptosis, and exert various immunomodulatory and inflammatory effects. As such, they are also clinically relevant, both as therapeutics and as targets of inhibition for the treatment of various autoimmune diseases and cancer. Mouse IFN-β is a ~20 kD monomeric glycoprotein. It has 50 % amino acid sequence homology with mouse IFN-α, its closest related protein, and 62 % homology with human IFN-β. IFN-β is currently the therapeutic of choice for treating multiple sclerosis.
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IFNB1 Antibody Target Details IFNB1 Handling References for anti-IFNB1 Antibody (ABIN2665064) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details References for anti-IFNB1 Antibody (ABIN2665064) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IFNB1 Antibody (ABIN2665064)

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details Handling Images back to top
Background publications

Nagarajan: "Induction and function of IFNβ during viral and bacterial infection." in: Critical reviews in immunology, Vol. 31, Issue 6, pp. 459-74, 2012

Creasy, McCoy: "Cytokines regulate cysteine cathepsins during TLR responses." in: Cellular immunology, Vol. 267, Issue 1, pp. 56-66, 2011

Zaric, Coulter, Shelburne, Fulton, Zaric, Scott, Lappin, Fitzgerald, Irwin, Taggart: "Altered Toll-like receptor 2-mediated endotoxin tolerance is related to diminished interferon beta production." in: The Journal of biological chemistry, Vol. 286, Issue 34, pp. 29492-500, 2011

Sow, Alvarez, Gross, Satoskar, Schlesinger, Zwilling, Lafuse: "Role of STAT1, NF-kappaB, and C/EBPbeta in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-gamma." in: Journal of leukocyte biology, Vol. 86, Issue 5, pp. 1247-58, 2009

Honda, Yanai, Takaoka, Taniguchi: "Regulation of the type I IFN induction: a current view." in: International immunology, Vol. 17, Issue 11, pp. 1367-78, 2005

Images

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details Handling References for anti-IFNB1 Antibody (ABIN2665064) back to top
Supplier Images
Western Blotting (WB) image for anti-IFNB1 antibody (Interferon, beta 1, Fibroblast) (ABIN2665064) anti-Interferon, beta 1, Fibroblast (IFNB1) antibody