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anti-Human IL-6 Receptor antibody for Immunohistochemistry

Recommended IL-6 Receptor Antibody (supplied by: Log in to see )

Antigen
Interleukin-6 Receptor (IL6R) Antibodies
  • CD126
  • gp80
  • IL-6R
  • IL-6R-1
  • IL-6RA
  • il-6ra
  • IL-6Ralpha
  • IL6Q
  • Il6r
  • IL6R
  • IL6R1
  • IL6RA
  • Il6ra
  • IL6RQ
Reactivity
Human
153
67
44
1
Host
Mouse
105
88
32
15
1
Clonality
Monoclonal
Conjugate
This IL-6 Receptor antibody is conjugated to PerCP-Cy5.5
22
14
12
10
5
4
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
101
101
81
43
38
27
26
24
18
13
11
10
8
6
4
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN2659946
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0011340706 ABIN1873216 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN255790 ICC FACS IHC (fro) IF IP IHC ELISA Mouse IgG1 Log in to see B-R6
0.0011340706 ABIN2659947 FACS IF IHC PerCP-Cy5.5 Mouse IgG1 kappa Log in to see UV4 3
0.0011340706 ABIN1583038 IHC ELISA WB Rabbit Log in to see Polyclonal
0.0011340706 ABIN2467041 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN2404334 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN2882081 IHC Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN4325584 IF IHC IHC (p) WB Mouse IgG1 Log in to see 2F4
0.0011340706 ABIN2222575 FACS IP IHC ELISA Mouse IgG1 Log in to see 3H1836
0.0011340706 ABIN2292041 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN1722534 Func FACS IHC ELISA Mouse IgG1 Log in to see B-F19
0.0011340706 ABIN2887024 IHC Rabbit Log in to see Polyclonal
0.0011340706 ABIN2697669 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN4325571 ELISA FACS ICC IF IHC IHC (fro) IP DyLight 350 Mouse IgG1 Log in to see B-R6
0.0011340706 ABIN4325572 ELISA FACS ICC IF IHC IHC (fro) IP DyLight 405 Mouse IgG1 Log in to see B-R6
0.0011340706 ABIN4325573 ELISA FACS ICC IF IHC IHC (fro) IP PE Mouse IgG1 Log in to see B-R6
0.0011340706 ABIN4325574 ELISA FACS ICC IF IHC IHC (fro) IP PerCP Mouse IgG1 Log in to see B-R6
0.0011340706 ABIN4325575 ELISA FACS ICC IF IHC IHC (fro) IP Allophycocyanin Mouse IgG1 Log in to see B-R6
0.0011340706 ABIN4325576 ELISA FACS ICC IF IHC IHC (fro) IP DyLight 755 Mouse IgG1 Log in to see B-R6
0.0011340706 ABIN4325577 ELISA FACS ICC IF IHC IHC (fro) IP DyLight 488 Mouse IgG1 Log in to see B-R6

Top referenced anti-IL-6 Receptor antibody for Immunohistochemistry

Similar anti-IL-6 Receptor Antibodies

Application / Reactivity Human
ELISA 73 Antibodies
ELISA (Capture) 2 Antibodies
ELISA (Detection) 1 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 80 Antibodies
Functional Studies (Func) 8 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 16 Antibodies
Immunofluorescence (IF) 23 Antibodies
Immunohistochemistry (IHC) 37 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 27 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 7 Antibodies
Immunoprecipitation (IP) 26 Antibodies
Intracellular Flow Cytometry (ICFC) 4 Antibodies
Mass Cytometry (CyTOF) 1 Antibodies
Neutralization (Neut) 11 Antibodies

General

Antigen Interleukin-6 Receptor (IL6R) Antibodies
Reactivity Human
(153), (67), (44), (1)
Host Mouse
(105), (88), (32), (15), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL-6 Receptor antibody is conjugated to PerCP-Cy5.5
(22), (14), (12), (10), (5), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
(101), (101), (81), (43), (38), (27), (26), (24), (18), (13), (11), (10), (8), (6), (4), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-IL-6 Receptor Antibody

Target Details IL-6 Receptor Application Details Handling References for anti-IL-6 Receptor Antibody (ABIN2659946) Images
Purification The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
Clone UV4
Isotype IgG1 kappa

Target Details IL-6 Receptor

Product Details anti-IL-6 Receptor Antibody Application Details Handling References for anti-IL-6 Receptor Antibody (ABIN2659946) Images back to top
Antigen
Alternative Name CD126 (IL6R Antibody Abstract)
Background CD126 is an 80 kD IL-6 receptor α chain also known as IL-6R. It is a member of the immunoglobulin superfamily that is expressed on plasma cells, T cells, activated B cells, monocytes, granulocytes, hepatocytes, epithelial cells, and fibroblasts. Functional IL-6 receptors are formed by the non-covalent association of CD126 and the IL-6 receptor β chain (CD130 or gp130). CD126 binds IL-6 with low affinity but does not signal. The β chain (gp130, CD130) does not bind IL-6 by itself but associates with the α-chain/IL-6 complex to initiate signal transduction. IL-6 binding to the receptor complex results in the stimulation of B and T cells, and hematopoietic precursor proliferation and differentiation. A soluble form of CD126 has been found in human serum.
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Handling References for anti-IL-6 Receptor Antibody (ABIN2659946) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details References for anti-IL-6 Receptor Antibody (ABIN2659946) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IL-6 Receptor Antibody (ABIN2659946)

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling Images back to top
Background publications

Boulanger, Chow, Brevnova, Garcia: "Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex." in: Science (New York, N.Y.), Vol. 300, Issue 5628, pp. 2101-4, 2003

Taga, Kishimoto: "Gp130 and the interleukin-6 family of cytokines." in: Annual review of immunology, Vol. 15, pp. 797-819, 1997

Gaillard, Bataille, Brailly, Zuber, Yasukawa, Attal, Maruo, Taga, Kishimoto, Klein: "Increased and highly stable levels of functional soluble interleukin-6 receptor in sera of patients with monoclonal gammopathy." in: European journal of immunology, Vol. 23, Issue 4, pp. 820-4, 1993

Images

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling References for anti-IL-6 Receptor Antibody (ABIN2659946) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-IL-6 Receptor antibody (Interleukin-6 Receptor)  (PerCP-Cy5.5) (ABIN2659946) anti-Interleukin-6 Receptor (IL6R) antibody (PerCP-Cy5.5)
Flow Cytometry (FACS) image for anti-IL-6 Receptor antibody (Interleukin-6 Receptor)  (PerCP-Cy5.5) (ABIN2659946) anti-Interleukin-6 Receptor (IL6R) antibody (PerCP-Cy5.5) (Image 2)