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|Antigen||Interleukin-6 Receptor (IL6R) Antibodies|
|Epitope||AA 20-357 Alternatives|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This IL-6 Receptor antibody is un-conjugated Alternatives|
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
|3 references available|
|Supplier||Log in to see|
Product Details anti-IL-6 Receptor AntibodyTarget Details IL-6 Receptor Application Details Handling References for anti-IL-6 Receptor antibody (ABIN4899509) Images
|Specificity||Detects mouse IL-6 R alpha in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human IL-6 R alpha is observed.|
|Purification||Protein A or G purified from hybridoma culture supernatant|
|Sterility||0.2 μm filtered|
|Immunogen||Mouse myeloma cell line NS0-derived recombinant mouse IL-6 R alpha , Leu20-Glu357, Accession # P22272|
Target Details IL-6 ReceptorProduct Details anti-IL-6 Receptor Antibody Application Details Handling References for anti-IL-6 Receptor antibody (ABIN4899509) Images back to top
|Alternative Name||IL-6 R alpha (IL6R Antibody Abstract)|
|Pathways||JAK-STAT Signaling, Autophagy, Growth Factor Binding|
Application DetailsProduct Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Handling References for anti-IL-6 Receptor antibody (ABIN4899509) Images back to top
Flow Cytometry 2.5 μg/10^6 cells
Immunocytochemistry 8-25 μg/mL
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details References for anti-IL-6 Receptor antibody (ABIN4899509) Images back to top
|Reconstitution||Reconstitute at 0.5 mg/mL in sterile PBS.|
|Buffer||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C,-20 °C,-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-IL-6 Receptor antibody (ABIN4899509)Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling Images back to top
|Product cited in:||
Ke, Zhang, Liu, Liu, Yan, Xu, Bai, Zhu, Lou, Wang, Shi, Jiang, Su, Wang: "Autocrine interleukin-6 drives skin-derived mesenchymal stem cell trafficking via regulating voltage-gated Ca(2+) channels." in: Stem cells (Dayton, Ohio), Vol. 32, Issue 10, pp. 2799-810, 2014 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)).
Bailey, Huang, Kam, Farzan: "Ifitm3 limits the severity of acute influenza in mice." in: PLoS pathogens, Vol. 8, Issue 9, pp. e1002909, 2012 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).
Matsumoto, Hara, Mitsuyama, Yamamoto, Tsuruta, Sata, Scheller, Rose-John, Kado, Takada et al.: "Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 3, pp. 1543-51, 2010 Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Mouse (Murine)).