anti-Mouse (Murine) IL-6 Receptor antibody for Western Blotting

Recommended IL-6 Receptor Antibody (supplied by: Log in to see )

Antigen
Interleukin-6 Receptor (IL6R) Antibodies
  • IL6R
  • il-6ra
  • CD126
  • IL-6R-1
  • IL-6RA
  • IL6Q
  • IL6RA
  • IL6RQ
  • gp80
  • IL6R1
  • Il6ra
  • IL-6Ralpha
  • IL-6R
  • Il6r
  • interleukin 6 receptor
  • interleukin 6 receptor-like
  • interleukin 6 receptor, alpha
  • IL6R
  • il6r
  • Il6r
  • LOC100347752
  • Il6ra
Epitope
AA 44-357
32
24
19
15
10
7
7
6
6
5
5
5
5
5
5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
200
87
45
1
Host
Rabbit
146
94
45
21
2
Clonality
Polyclonal
Conjugate
This IL-6 Receptor antibody is un-conjugated
26
17
15
12
10
9
7
7
5
5
5
5
4
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
136
134
101
71
40
24
24
22
19
13
11
10
10
8
8
8
4
2
2
2
2
2
1
Supplier
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Catalog No. ABIN2000701
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1093338 ABIN1859439 ICC IHC IP WB Rabbit IgG AA 52-204 Log in to see Polyclonal
3.1093338 ABIN1175054 ICC IHC IP WB Rabbit IgG AA 205-347 Log in to see Polyclonal
1 ABIN4899510 CyTOF ELISA (Capture) FACS IHC Neut WB Goat IgG AA 20-357 Log in to see Polyclonal 6
1 ABIN734693 IF (p) IHC (p) WB Rabbit IgG AA 386-430 Log in to see Polyclonal 1
1 ABIN2660934 ELISA (Capture) ELISPOT (Capture) ICFC Neut IHC WB Biotin Rat IgG2b kappa Log in to see D7715A7 11
1 ABIN4899507 ELISA (Detection) FACS WB Biotin Goat IgG AA 20-357 Log in to see Polyclonal 3
1 ABIN734702 IHC (p) WB HRP Rabbit IgG AA 386-430 Log in to see Polyclonal
1 ABIN360909 IHC (fro) WB Rat IgG2 Extracellular Domain Log in to see 14F33
1 ABIN439445 IHC (fro) IHC WB Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN734695 IHC (p) WB Biotin Rabbit IgG AA 386-430 Log in to see Polyclonal
1 ABIN327368 ELISA WB Rat IgG1 Extracellular Domain Log in to see
1 ABIN2624198 ELISA WB Biotin Rabbit IgG AA 52-204 Log in to see Polyclonal
1 ABIN2624200 ELISA WB Biotin Rabbit IgG AA 205-347 Log in to see Polyclonal
1 ABIN2624203 ELISA WB FITC Rabbit IgG AA 52-204 Log in to see Polyclonal
1 ABIN2624207 ELISA WB FITC Rabbit IgG AA 205-347 Log in to see Polyclonal
1 ABIN2609956 ELISA WB Rabbit IgG AA 205-347 Log in to see Polyclonal
1 ABIN2609959 ELISA WB Rabbit IgG AA 52-204 Log in to see Polyclonal
1 ABIN2660933 ELISA (Capture) ELISPOT (Capture) ICFC Neut IHC WB Biotin Rat IgG2b kappa Log in to see D7715A7 11
1 ABIN5606327 IHC IHC (fro) WB DyLight 488 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606322 IHC IHC (fro) WB Alexa Fluor 647 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33

General

Antigen Interleukin-6 Receptor (IL6R) Antibodies
Epitope AA 44-357
(32), (24), (19), (15), (10), (7), (7), (6), (6), (5), (5), (5), (5), (5), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(200), (87), (45), (1)
Host Rabbit
(146), (94), (45), (21), (2)
Clonality
Polyclonal
Conjugate This IL-6 Receptor antibody is un-conjugated
(26), (17), (15), (12), (10), (9), (7), (7), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Western Blotting (WB)
(136), (134), (101), (71), (40), (24), (24), (22), (19), (13), (11), (10), (10), (8), (8), (8), (4), (2), (2), (2), (2), (2), (1)
Pubmed 1 reference available
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Product Details anti-IL-6 Receptor Antibody

Target Details IL-6 Receptor Application Details Handling References for anti-IL-6 Receptor antibody (ABIN2000701) Images
Specificity Mouse IL6RA / CD126
Characteristics Produced in rabbits immunized with purified, recombinant Mouse IL6RA / CD126 (rM IL6RA, ABIN2007611 NP_034689.2, Ile 44-Glu 357,. IL6RA specific IgG was purified by mouse IL6RA affinity chromatography.
Purification purified by affinity chromatography
Sterility 0.2 μm filtered
Immunogen Recombinant Mouse IL6RA protein (ABIN2007611)
Isotype IgG

Target Details IL-6 Receptor

Product Details anti-IL-6 Receptor Antibody Application Details Handling References for anti-IL-6 Receptor antibody (ABIN2000701) Images back to top
Antigen
Alternative Name IL6R (IL6R Antibody Abstract)
Background Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (sIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a sIL-6R protein are able to mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signalling. Through this so-called 'trans-signalling' mechanism, IL-6 is able to stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and sIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.
NCBI Accession NP_034689.2
Research Area Stem Cells, Hematopoietic Progenitors, Innate Immunity, Cytokines, Immunology
Pathways JAK-STAT Signaling, Autophagy, Growth Factor Binding

Application Details

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Handling References for anti-IL-6 Receptor antibody (ABIN2000701) Images back to top
Application Notes WB: 10-20 μg/mL
ELISA: 0.5-1.0 μg/mL
This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Mouse IL6RA. The detection limit for Mouse IL6RA is 0.00245 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details References for anti-IL-6 Receptor antibody (ABIN2000701) Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

References for anti-IL-6 Receptor antibody (ABIN2000701)

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling Images back to top
Background publications

Stauber, Barill, Stauber, Miller: "Isotonic dynamometry for the assessment of power and fatigue in the knee extensor muscles of females." in: Clinical physiology (Oxford, England), Vol. 20, Issue 3, pp. 225-33, 2000

Images

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling References for anti-IL-6 Receptor antibody (ABIN2000701) back to top
Supplier Images
Western Blotting (WB) image for anti-Interleukin-6 Receptor (IL6R) (AA 44-357) antibody (ABIN2000701) anti-Interleukin-6 Receptor (IL6R) (AA 44-357) antibody