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anti-Human IL2RG antibody for Immunofluorescence

Recommended IL2RG Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 Receptor, gamma (IL2RG) Antibodies
  • Ab2-183
  • CD132
  • Cd132
  • CIDX
  • gamma(c)
  • gc
  • IL-2RG
  • IMD4
  • P64
  • SCIDX
  • SCIDX1
  • [g]c
Reactivity
Human
95
49
25
2
Host
Rat
84
26
9
Clonality
Monoclonal
Conjugate
This IL2RG antibody is un-conjugated
12
9
9
5
4
3
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
60
45
35
11
9
5
4
2
2
1
1
1
Supplier
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Catalog No. ABIN2665537
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Top referenced anti-IL2RG antibody for Immunofluorescence

Similar anti-IL2RG Antibodies

Application / Reactivity Human
ELISA 39 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 23 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 10 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies
Neutralization (Neut) 1 Antibodies
Western Blotting (WB) 59 Antibodies

General

Antigen Interleukin 2 Receptor, gamma (IL2RG) Antibodies
Reactivity Human
(95), (49), (25), (2)
Host Rat
(84), (26), (9)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL2RG antibody is un-conjugated
(12), (9), (9), (5), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
(60), (45), (35), (11), (9), (5), (4), (2), (2), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-IL2RG Antibody

Target Details IL2RG Application Details Handling References for anti-IL2RG Antibody (ABIN2665537) Images
Brand LEAF™
Cross-Reactivity Dog (Canine)
Purification The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level

Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.

Clone TUGh4
Isotype IgG2b kappa

Target Details IL2RG

Product Details anti-IL2RG Antibody Application Details Handling References for anti-IL2RG Antibody (ABIN2665537) Images back to top
Antigen
Alternative Name CD132 (IL2RG Antibody Abstract)
Background CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, also known as common γ chain (γc), or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL2RG Antibody Target Details IL2RG Handling References for anti-IL2RG Antibody (ABIN2665537) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL2RG Antibody Target Details IL2RG Application Details References for anti-IL2RG Antibody (ABIN2665537) Images back to top
Concentration 1.0 mg/mL
Preservative Azide free
Handling Advice This LEAF™ solution contains no preservative, handle under aseptic conditions
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IL2RG Antibody (ABIN2665537)

Product Details anti-IL2RG Antibody Target Details IL2RG Application Details Handling Images back to top
Background publications

Habib, Senadheera, Weinberg, Kaushansky: "The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3." in: Biochemistry, Vol. 41, Issue 27, pp. 8725-31, 2002

Itano, Tsuchiya, Morita, Fujie, Ishii, Yanagisawa, Ohashi, Minegishi, Sugamura, Konno: "IL-2 receptor gamma chain expression on CD34 positive hematopoietic progenitor cells from bone marrow and cord blood." in: The Tohoku journal of experimental medicine, Vol. 178, Issue 4, pp. 389-98, 1996

Kawahara, Minami, Miyazaki, Ihle, Taniguchi: "Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 19, pp. 8724-8, 1995

Matthews, Clark, Herbert, Morgan, Armitage, Kinnon, Minty, Grabstein, Caput, Ferrara: "Function of the interleukin-2 (IL-2) receptor gamma-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15." in: Blood, Vol. 85, Issue 1, pp. 38-42, 1995

Nakarai, Robertson, Streuli, Wu, Ciardelli, Smith, Ritz: "Interleukin 2 receptor gamma chain expression on resting and activated lymphoid cells." in: The Journal of experimental medicine, Vol. 180, Issue 1, pp. 241-51, 1994

Kondo, Takeshita, Ishii, Nakamura, Watanabe, Arai, Sugamura: "Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4." in: Science (New York, N.Y.), Vol. 262, Issue 5141, pp. 1874-7, 1994