IL2RG antibody

Catalog No. ABIN7457857

Product Details anti-IL2RG Antibody

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL2RG antibody is un-conjugated

Application: Flow Cytometry (FACS)

Purification: Purified

Clone: 3E12

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Matching Isotype Control: Purified Rat IgG2b, κ Isotype Control (ABIN7469856)

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C. Do not freeze.

Target Details for IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: CD132 (IL2RG Products)

Synonyms: Ab2-183 antibody, Cd132 antibody, CD132 antibody, CIDX antibody, IL-2RG antibody, IMD4 antibody, P64 antibody, SCIDX antibody, SCIDX1 antibody, [g]c antibody, gamma(c) antibody, gc antibody, interleukin 2 receptor subunit gamma antibody, interleukin 2 receptor subunit gamma L homeolog antibody, interleukin 2 receptor, gamma chain antibody, IL2RG antibody, il2rg.L antibody, Il2rg antibody

Background: Cytokine receptor common subunit gamma,Il2rg,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132,CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Gene ID: 16186

UniProt: P34902

Pathways: JAK-STAT Signaling, Growth Factor Binding