You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mouse (Murine) IL2RG antibody for Neutralization

Recommended IL2RG Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 Receptor, gamma (IL2RG) Antibodies
  • Ab2-183
  • CD132
  • Cd132
  • CIDX
  • gamma(c)
  • gc
  • IL-2RG
  • IMD4
  • P64
  • SCIDX
  • SCIDX1
  • [g]c
Reactivity
Mouse (Murine)
96
48
25
2
Host
Rat
84
26
9
Clonality
Monoclonal
Conjugate
This IL2RG antibody is un-conjugated
12
9
9
5
4
3
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Neutralization (Neut)
60
45
35
11
10
5
3
2
2
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Catalog No. ABIN1177316
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00086911913 ABIN1177315 FACS Neut Rat IgG2b, kappa Log in to see TUGm2 3
0.00086911913 ABIN2688956 BR FACS Neut Biotin Rat IgG2b, kappa Log in to see TUGm2 3

Top referenced anti-IL2RG antibody for Neutralization

Similar anti-IL2RG Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 1 Antibodies
ELISA 11 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 13 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 6 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies
Intracellular Flow Cytometry (ICFC) 1 Antibodies
Neutralization (Neut) 3 Antibodies
Western Blotting (WB) 14 Antibodies

General

Antigen Interleukin 2 Receptor, gamma (IL2RG) Antibodies
Reactivity Mouse (Murine)
(96), (48), (25), (2)
Host Rat
(84), (26), (9)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL2RG antibody is un-conjugated
(12), (9), (9), (5), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Neutralization (Neut)
(60), (45), (35), (11), (10), (5), (3), (2), (2), (1), (1), (1), (1)
Pubmed 6 references available
Supplier Log in to see

Product Details anti-IL2RG Antibody

Target Details IL2RG Application Details Handling References for anti-IL2RG Antibody (ABIN1177316) Images
Brand BD Pharmingen™
Characteristics Neutralization Activity: Neutralization activity may be measured with a proliferation assay using 60 pg/mL recombinant human IL-15 (Cat. No. 560254) to stimulate murine CTLL-2 cells at 2x10^4 cells/mL as indicator cells (i.e preincubation of the antibody with recombinant human IL-15 for 60 minutes).
50% Neutralization (ND50) at 0.02 - 3.0 µg/mL
> 85% Neutralization at 2-20 µg/mL
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
Clone 4G3
Isotype IgG2a, kappa

Target Details IL2RG

Product Details anti-IL2RG Antibody Application Details Handling References for anti-IL2RG Antibody (ABIN1177316) Images back to top
Antigen
Alternative Name CD132 (IL2RG Antibody Abstract)
Background The 4G3 antibody reacts with the common gamma subunit (gammac) shared by the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors also known as CD132. This receptor is expressed constitutively at low levels on most lymphocytes, myeloid cells, embryonic thymocytes and lymphoid cell lines, but not non-lymphoid cells. The gammac receptor is a 75 - 80 kD transmembrane glycoprotein which mediates signal transducing activities of cytokine receptor complexes with which it is associated.
Synonyms: Common gamma chain, gammac
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL2RG Antibody Target Details IL2RG Handling References for anti-IL2RG Antibody (ABIN1177316) Images back to top
Restrictions For Research Use only

Handling

Product Details anti-IL2RG Antibody Target Details IL2RG Application Details References for anti-IL2RG Antibody (ABIN1177316) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
Preservative Azide free
Storage 4 °C
Storage Comment Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

References for anti-IL2RG Antibody (ABIN1177316)

Product Details anti-IL2RG Antibody Target Details IL2RG Application Details Handling Images back to top
Product cited in:

He, Malek: "The IL-2 receptor gamma c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. Implication for the structure of the IL-4 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 1, pp. 9-12, 1995

He, Adkins, Furse, Malek: "Expression and function of the gamma c subunit of the IL-2, IL-4, and IL-7 receptors. Distinct interaction of gamma c in the IL-4 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 4, pp. 1596-605, 1995

Malek, Furse, Fleming, Fadell, He: "Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 15, Issue 5, pp. 447-54, 1995

Kondo, Takeshita, Higuchi, Nakamura, Sudo, Nishikawa, Sugamura: "Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes." in: Science (New York, N.Y.), Vol. 263, Issue 5152, pp. 1453-4, 1994

Kondo, Takeshita, Ishii, Nakamura, Watanabe, Arai, Sugamura: "Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4." in: Science (New York, N.Y.), Vol. 262, Issue 5141, pp. 1874-7, 1994

Gillis, Ferm, Ou, Smith: "T cell growth factor: parameters of production and a quantitative microassay for activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 120, Issue 6, pp. 2027-32, 1978