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anti-Cow (Bovine) PTPN6 antibody for Western Blotting

Recommended PTPN6 Antibody (supplied by: Log in to see )

Antigen
Protein-tyrosine Phosphatase 1C (PTPN6) Antibodies
  • SHP
  • SHP-1
  • Shp1
  • HCP
  • HCPH
  • HPTP1C
  • PTP-1C
  • SH-PTP1
  • SHP-1L
  • SHP1
  • Hcph
  • Ptp1C
  • hcp
  • me
  • motheaten
  • Ptph6
  • Shp-1
  • DRPLA
  • protein tyrosine phosphatase, non-receptor type 6
  • nuclear receptor subfamily 0, group B, member 2
  • PTPN6
  • Nr0b2
  • Ptpn6
Epitope
Middle Region
26
23
15
8
8
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
183
90
85
6
3
1
1
1
1
1
1
Host
Rabbit
118
33
33
Clonality
Polyclonal
Conjugate
This PTPN6 antibody is un-conjugated
7
7
7
3
3
2
2
2
2
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
134
77
55
30
29
28
10
8
6
5
4
1
1
Options
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Available images

Catalog No. ABIN2788789
$ 289.00
Plus shipping costs $45.00

Similar anti-PTPN6 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Dog (Canine) Cow (Bovine) Horse (Equine) Guinea Pig Rabbit Zebrafish
Immunofluorescence (fixed cells) (IF/ICC) 4 Antibodies 2 Antibodies 2 Antibodies
Western Blotting (WB) 134 Antibodies 53 Antibodies 50 Antibodies 6 Antibodies 1 Antibodies 1 Antibodies 1 Antibodies 1 Antibodies 1 Antibodies
Immunoprecipitation (IP) 9 Antibodies 6 Antibodies 4 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 30 Antibodies 15 Antibodies 16 Antibodies 1 Antibodies

General

Antigen Protein-tyrosine Phosphatase 1C (PTPN6) Antibodies
Epitope Middle Region
(26), (23), (15), (8), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
(183), (90), (85), (6), (3), (1), (1), (1), (1), (1), (1)
Host Rabbit
(118), (33), (33)
Clonality
Polyclonal
Conjugate This PTPN6 antibody is un-conjugated
(7), (7), (7), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Western Blotting (WB)
(134), (77), (55), (30), (29), (28), (10), (8), (6), (5), (4), (1), (1)
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Product Details anti-PTPN6 Antibody

Target Details PTPN6 Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN982456
Sequence WEEFESLQKQ EVKNLHQRLE GQRPENKGKN RYKNILPFDH SRVILQGRDS
Predicted Reactivity Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%
Characteristics This is a rabbit polyclonal antibody against PTPN6. It was validated on Western Blot.
Purification Affinity Purified

Target Details PTPN6

Product Details anti-PTPN6 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PTPN6 (PTPN6 Antibody Abstract)
Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling.
Alias Symbols: HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1
Protein Interaction Partner: FHL3, UBC, Siglece, PANK4, SAMD4B, SMAD3, TXN, CD300LF, SIGLEC12, LILRB4, LILRB2, TREML1, KIR2DL3, SPATA2, C6orf25, KLRAP1, TMEM62, PILRB, SIGLEC10, FCGR2B, CUZD1, BTLA, SIGLEC11, SLAMF6, TLR10, GAB2, PAG1, PILRA, CLEC4A, KIR2DL5A, ACTN4, BLNK, STAT5B, IR
Protein Size: 595
Molecular Weight 65 kDa
Gene ID 5777
NCBI Accession NM_002831, NP_002822
UniProt P29350
Pathways JAK-STAT Signaling, TLR Signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-PTPN6 Antibody Target Details PTPN6 Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 595 AA

Restrictions For Research Use only

Handling

Product Details anti-PTPN6 Antibody Target Details PTPN6 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-PTPN6 Antibody Target Details PTPN6 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-PTPN6 antibody (Protein-tyrosine Phosphatase 1C) (Middle Region) (ABIN2788789) anti-Protein-tyrosine Phosphatase 1C (PTPN6) (Middle Region) antibody