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anti-Guinea Pig SOCS1 antibody for Western Blotting

Recommended SOCS1 Antibody (supplied by: Log in to see )

Antigen
Suppressor of Cytokine Signaling 1 (SOCS1) Antibodies
  • CIS1
  • cis1
  • CISH1
  • cish1
  • Cish1
  • Cish7
  • jab
  • JAB
  • LOC100228306
  • Socs-1
  • socs-1
  • SOCS-1
  • SOCS1
  • socs1
  • socs1b
  • SSI-1
  • ssi-1
  • SSI1
  • ssi1
  • TIP3
  • tip3
  • zgc:91868
Epitope
N-Term
60
26
13
5
4
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
151
65
54
7
7
3
1
1
Host
Rabbit
135
18
10
Clonality
Polyclonal
Conjugate
This SOCS1 antibody is un-conjugated
7
7
6
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
140
55
33
29
11
10
8
8
4
4
2
1
Supplier
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Catalog No. ABIN2777164
$ 229.00
Plus shipping costs $45.00

Top referenced anti-SOCS1 antibody for Western Blotting

  • Cow (Bovine) Polyclonal SOCS1 Primary Antibody for IHC, WB - ABIN2777164 (1 Publications): Melzner, Weniger, Bucur, Brüderlein, Dorsch, Hasel, Leithäuser, Ritz, Dyer, Barth, Möller: Biallelic deletion within 16p13.13 including SOCS-1 in Karpas1106P mediastinal B-cell lymphoma line is associated with delayed degradation of JAK2 protein. in International journal of cancer. Journal international du cancer 2006 (PubMed)

Similar anti-SOCS1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Cow (Bovine) Dog (Canine) Guinea Pig Horse (Equine) Pig (Porcine) Rabbit
Western Blotting (WB) 133 Antibodies 51 Antibodies 43 Antibodies 8 Antibodies 8 Antibodies 1 Antibodies 2 Antibodies 4 Antibodies 2 Antibodies
Immunoprecipitation (IP) 4 Antibodies 6 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 30 Antibodies 16 Antibodies 12 Antibodies 3 Antibodies 3 Antibodies
Immunohistochemistry (IHC) 15 Antibodies 35 Antibodies 3 Antibodies

General

Antigen Suppressor of Cytokine Signaling 1 (SOCS1) Antibodies
Epitope N-Term
(60), (26), (13), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(151), (65), (54), (7), (7), (3), (1), (1)
Host Rabbit
(135), (18), (10)
Clonality
Polyclonal
Conjugate This SOCS1 antibody is un-conjugated
(7), (7), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(140), (55), (33), (29), (11), (10), (8), (8), (4), (4), (2), (1)
Pubmed 1 reference available
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Product Details anti-SOCS1 Antibody

Target Details SOCS1 Application Details Handling References for anti-SOCS1 Antibody (ABIN2777164) Images
Sequence RRPEPSSSSS SSPAAPARPR PCPAVPAPAP GDTHFRTFRS HADYRRITRA
Predicted Reactivity Predicted Homology Based On Immunogen Sequence:
Pig: 100%; Rat: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 93%; Dog: 92%; Horse: 90%
Characteristics This is a rabbit polyclonal antibody against SOCS1. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SOCS1

Target Details SOCS1

Product Details anti-SOCS1 Antibody Application Details Handling References for anti-SOCS1 Antibody (ABIN2777164) Images back to top
Antigen
Alternative Name SOCS1 (SOCS1 Antibody Abstract)
Background SOCS1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. SOCS1 functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of its gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Molecular Weight 23 kDa
Gene ID 8651
NCBI Accession NP_003736, NM_003745
UniProt O15524
Research Area Chromatin and Nuclear Signaling, Signaling, Cytokines
Pathways JAK-STAT Signaling, Interferon-gamma Pathway, TLR Signaling

Application Details

Product Details anti-SOCS1 Antibody Target Details SOCS1 Handling References for anti-SOCS1 Antibody (ABIN2777164) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 211 AA

Restrictions For Research Use only

Handling

Product Details anti-SOCS1 Antibody Target Details SOCS1 Application Details References for anti-SOCS1 Antibody (ABIN2777164) Images back to top
Format Liquid
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SOCS1 Antibody (ABIN2777164)

Product Details anti-SOCS1 Antibody Target Details SOCS1 Application Details Handling Images back to top
Background publications

Melzner, Weniger, Bucur, Brüderlein, Dorsch, Hasel, Leithäuser, Ritz, Dyer, Barth, Möller: "Biallelic deletion within 16p13.13 including SOCS-1 in Karpas1106P mediastinal B-cell lymphoma line is associated with delayed degradation of JAK2 protein." in: International journal of cancer. Journal international du cancer, Vol. 118, Issue 8, pp. 1941-4, 2006

Images

Product Details anti-SOCS1 Antibody Target Details SOCS1 Application Details Handling References for anti-SOCS1 Antibody (ABIN2777164) back to top
Supplier Images
Western Blotting (WB) image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (N-Term) (ABIN2777164) WB Suggested Anti-SOCS1 Antibody Titration: 1.25ug/ml
Sample Type...
Western Blotting (WB) image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (N-Term) (ABIN2777164) anti-Suppressor of Cytokine Signaling 1 (SOCS1) (N-Term) antibody (Image 2)
 image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (N-Term) (ABIN2777164) anti-Suppressor of Cytokine Signaling 1 (SOCS1) (N-Term) antibody (Image 3)
Western Blotting (WB) image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (N-Term) (ABIN2777164) Lanes: 1. Mouse WT brain extract (841 µg) 2. Rat brain extract (841 µg)
Primary...
Western Blotting (WB) image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (N-Term) (ABIN2777164) SOCS1 Antibody - N-terminal region (ARP42147_T100) validated by WB using Huh7 Cells t...