SOCS1 antibody (C-Term)

Catalog No. ABIN548558

Product Details anti-SOCS1 Antibody

Target: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of SOCS1.

Cross-Reactivity: Human, Mouse, Rabbit, Rat

Immunogen: A synthetic peptide corresponding to amino acids at C-terminus of human SOCS1.

Isotype: IgG

Application Details

Application Notes: Western Blot (1-2 μg/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 0.9 mg NaCl, 0.2 mg Na₂HPO₄ (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

References for anti-SOCS1 antibody (ABIN548558)

Yoshida, Ogata, Kamio, Joo, Shiraishi, Tokunaga, Sata, Nagai, Yoshimura: "SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis." in: The Journal of experimental medicine, Vol. 199, Issue 12, pp. 1701-7, (2004) (PubMed).

Nagai, Naka, Terada, Komazaki, Yabe, Jin, Kawanami, Kishimoto, Konishi, Nakamura, Kobayashi, Emi: "Hypermethylation associated with inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human hepatoblastomas." in: Journal of human genetics, Vol. 48, Issue 2, pp. 65-9, (2003) (PubMed).

Target Details for SOCS1

Target: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Alternative Name: SOCS1 / JAB (SOCS1 Products)

Synonyms: socs1 antibody, zgc:91868 antibody, jab antibody, cis1 antibody, ssi1 antibody, tip3 antibody, cish1 antibody, ssi-1 antibody, socs-1 antibody, SOCS1 antibody, LOC100228306 antibody, socs1b antibody, CIS1 antibody, CISH1 antibody, JAB antibody, SOCS-1 antibody, SSI-1 antibody, SSI1 antibody, TIP3 antibody, Cish1 antibody, Cish7 antibody, Socs-1 antibody, suppressor of cytokine signaling 1a antibody, suppressor of cytokine signaling 1 antibody, suppressor of cytokine signaling 1 L homeolog antibody, socs1a antibody, socs1 antibody, SOCS1 antibody, socs1.L antibody, Socs1 antibody

Gene ID: 8651

Pathways: JAK-STAT Signaling, Interferon-gamma Pathway, TLR Signaling, Response to Growth Hormone Stimulus