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Browse our SOCS4 Proteins (SOCS4)

Full name:
Suppressor of Cytokine Signaling 4 Proteins (SOCS4)
On www.antibodies-online.com are 7 Suppressor of Cytokine Signaling 4 (SOCS4) Proteins from 4 different suppliers available. Additionally we are shipping SOCS4 Antibodies (85) and many more products for this protein. A total of 98 SOCS4 products are currently listed.
Synonyms:
3110032M18Rik, A730004F22Rik, AI427843, AU015727, AU015859, Socs4, socs4a, SOCS6, socs6l, Socs7, wu:fb77f06, zgc:64107
list all proteins Gene Name GeneID UniProt
Rat SOCS4 SOCS4 305828  
SOCS4 122809 Q8WXH5
SOCS4 67296 Q91ZA6

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SOCS4 Proteins (SOCS4) by Origin

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More Proteins for SOCS4 Interaction Partners

Human Suppressor of Cytokine Signaling 4 (SOCS4) interaction partners

  1. miR (show MLXIP Proteins)-25 promotes the migration and invasion of thyroid cancer cells by directly binding to the 3'-UTR of SOCS4 (show SOCS6 Proteins) that leads to the inhibition of SOCS4 (show SOCS6 Proteins).

  2. This study showed that increased protein levels of SOCS-4 (show SOCS6 Proteins) and SOCS-7 in Alzheimer's disease brains.

  3. SOCS4 (show SOCS6 Proteins) is a known inhibitor of epidermal growth factor (EGF (show EGF Proteins)) receptor (show EGFR Proteins) signalling, and functional studies demonstrated specific upregulation of EGF (show EGF Proteins)-dependent immune stimulation in affected family members.

  4. Identified is a conserved region of about 70 residues in the N-terminal domains of SOCS4 (show SOCS6 Proteins) and 5 that is predicted to be more ordered than the surrounding sequence.

  5. The expression of SOCS4 (show SOCS6 Proteins) seems to be controlled epigenetically and is often weakly expressed in gastric cancer tissue and cell lines. SOCS4 (show SOCS6 Proteins) methylation status could be a predictor of gastric cancer prognosis.

  6. Higher mRNA expression levels of SOCS1 (show SOCS1 Proteins), 3, 4 and 7 are significantly associated with earlier tumour stage and better clinical outcome in human breast cancer.

  7. These data suggest that miRNAs play an important role in the regulation of cytokine-inducible Src (show SRC Proteins) homology and SOCS (show CISH Proteins) expression in epithelial cells in response to C. parvum infection.

  8. the expression of SOCS5 (show SOCS5 Proteins) and its closest homolog SOCS4 (show SOCS6 Proteins) is elevated in cells following treatment with EGF (show EGF Proteins), similar to several negative feedback regulators of EGFR (show EGFR Proteins) whose expression is up-regulated upon receptor activation.

  9. The structure of the SOCS4 (show SOCS6 Proteins)-ElonginC-ElonginB complex reveals a distinct SOCS (show CISH Proteins) structural class.

Mouse (Murine) Suppressor of Cytokine Signaling 4 (SOCS4) interaction partners

  1. SOCS4 (show SOCS6 Proteins) is a critical regulator of anti-viral immunity.

  2. Identified is a conserved region of about 70 residues in the N-terminal domains of Socs4 (show SOCS6 Proteins) and 5 that is predicted to be more ordered than the surrounding sequence.

  3. Negative regulation of the JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) pathway is controlled by SOCS4 (show SOCS6 Proteins), which target members of negative feedback loops, to suppress follicle growth and development.

  4. Socs4 (show SOCS6 Proteins) is a hydroxylation substrate of FIH (show CASR Proteins) and promotes vascular differentiation via an oxygen-dependent mechanism.

SOCS4 Protein Profile

Protein Summary

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with SOCS4

  • suppressor of cytokine signaling 4 (socs4)
  • suppressor of cytokine signaling 6 (SOCS6)
  • suppressor of cytokine signaling 4 (Socs4)
  • suppressor of cytokine signaling 6b (socs6b)
  • suppressor of cytokine signaling 4 (SOCS4)
  • suppressor of cytokine signaling 7 (SOCS7)
  • 3110032M18Rik protein
  • A730004F22Rik protein
  • AI427843 protein
  • AU015727 protein
  • AU015859 protein
  • Socs4 protein
  • socs4a protein
  • SOCS6 protein
  • socs6l protein
  • Socs7 protein
  • wu:fb77f06 protein
  • zgc:64107 protein

Protein level used designations for SOCS4

suppressor of cytokine signaling 4 , suppressor of cytokine signaling 6 , suppressor of cytokine signaling 4-like , suppressor of cytokine signaling 6 protein , suppressor of cytokine signaling 6, like , suppressor of cytokine signaling 4a , SH2 domain containing SOCS box protein , SOCS-4 , SOCS-7 , suppressor of cytokine signaling 7 , suppressor of cytokine signalling 4

GENE ID SPECIES
100190867 Gasterosteus aculeatus
100357417 Oryctolagus cuniculus
100386210 Callithrix jacchus
305828 Rattus norvegicus
322950 Danio rerio
423557 Gallus gallus
452919 Pan troglodytes
549828 Xenopus (Silurana) tropicalis
696146 Macaca mulatta
797891 Danio rerio
100144313 Takifugu rubripes
100144385 Oryzias latipes
100514187 Sus scrofa
100590972 Nomascus leucogenys
122809 Homo sapiens
100302366 Sus scrofa
540412 Bos taurus
67296 Mus musculus
100171842 Pongo abelii
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