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anti-Mouse (Murine) STAT3 antibody for Immunoprecipitation

Recommended STAT3 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
  • 1110034C02Rik
  • APRF
  • Aprf
  • aprf
  • AW109958
  • hies
  • HIES
  • stat3
  • wu:fc15d02
  • wu:fl59g06
  • Xstat3
  • z-Stat3
Epitope
AA 1-175
112
95
85
28
21
17
16
16
14
13
13
12
8
5
5
5
5
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Dog (Canine), Frog, Human, Mouse (Murine), Rat (Rattus)
545
266
208
30
24
23
13
11
9
5
4
3
3
2
2
2
1
1
1
1
1
1
Host
Mouse
466
108
35
4
1
1
Clonality
Monoclonal
Conjugate
This STAT3 antibody is un-conjugated
24
22
18
13
12
11
8
5
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
503
239
216
80
76
69
53
32
23
13
12
12
9
7
3
3
2
2
2
2
1
1
1
1
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Catalog No. ABIN967808
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089556724 ABIN967809 IF IP IHC WB Mouse IgG1 AA 1-175 Log in to see 84-Stat3 5
0.00089556724 ABIN126898 EIA IHC (fro) IF IP WB Mouse IgG1 pTyr705 Log in to see 9-00E-012
0.00089556724 ABIN126896 EIA IHC (fro) IF IP WB Biotin Mouse IgG1 pTyr705 Log in to see 9-00E-012
0.00089556724 ABIN318127 IHC (p) IP WB Rabbit pTyr705 Log in to see Polyclonal
0.00089556724 ABIN1804660 IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal
0.00089556724 ABIN318126 IHC (p) IP WB Rabbit pSer727 Log in to see Polyclonal
0.00089556724 ABIN218705 FACS IP WB Mouse IgG1 pTyr705 Log in to see
0.00089556724 ABIN2705261 IP IHC WB Rabbit C-Term, pTyr705 Log in to see Polyclonal
0.00089556724 ABIN2705258 IP IHC WB Rabbit C-Term, pSer727 Log in to see Polyclonal
0.00089556724 ABIN2705260 IC IF IP IHC WB Rabbit C-Term Log in to see Polyclonal
0.00089556724 ABIN256912 ICC IF IHC (p) IP IHC WB Rabbit IgG Tyr705 Log in to see EP2147Y
0.00089556724 ABIN1830242 ICC IP IHC WB Rabbit IgG pTyr705 Log in to see 7H65
0.00089556724 ABIN218701 ICC IP ELISA WB Rabbit IgG pTyr705 Log in to see Polyclonal
0.00089556724 ABIN1830951 IP IHC WB Rabbit IgG pSer727 Log in to see Polyclonal
0.00089556724 ABIN2506001 IP IHC ELISA WB Rabbit IgG pTyr705 Log in to see Polyclonal
0.00089556724 ABIN223191 IP IHC WB Rabbit IgG pSer727 Log in to see Polyclonal
0.00089556724 ABIN1450386 IP IHC ELISA WB Rabbit IgG pTyr705, C-Term Log in to see Polyclonal
0.00089556724 ABIN218702 ICC FACS IP ELISA WB Rabbit IgG pTyr705 Log in to see Polyclonal
0.00089556724 ABIN3182149 ELISA IHC IP WB Rabbit IgG pSer727 Log in to see Polyclonal
0.00089556724 ABIN3182150 ELISA IHC IP WB Rabbit IgG pTyr705 Log in to see Polyclonal

Top referenced anti-STAT3 antibody for Immunoprecipitation

Similar anti-STAT3 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Dog (Canine) Chicken Frog
Western Blotting (WB) 454 Antibodies 202 Antibodies 158 Antibodies 20 Antibodies 8 Antibodies 2 Antibodies
Proximity Ligation Assay (PLA) 3 Antibodies
Intracellular Staining (ICS) 13 Antibodies 13 Antibodies 4 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies 2 Antibodies 2 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 9 Antibodies 54 Antibodies 50 Antibodies 30 Antibodies 5 Antibodies 2 Antibodies

General

Antigen Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
Epitope AA 1-175
(112), (95), (85), (28), (21), (17), (16), (16), (14), (13), (13), (12), (8), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Dog (Canine), Frog, Human, Mouse (Murine), Rat (Rattus)
(545), (266), (208), (30), (24), (23), (13), (11), (9), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(466), (108), (35), (4), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This STAT3 antibody is un-conjugated
(24), (22), (18), (13), (12), (11), (8), (5), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(503), (239), (216), (80), (76), (69), (53), (32), (23), (13), (12), (12), (9), (7), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-STAT3 Antibody

Target Details STAT3 Application Details Handling References for anti-STAT3 Antibody (ABIN967808) Images
Cross-Reactivity Human, Mouse (Murine), Dog (Canine), Chicken, Frog
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Rat Stat3 aa. 1-175
Clone 84-Stat3
Isotype IgG1

Target Details STAT3

Product Details anti-STAT3 Antibody Application Details Handling References for anti-STAT3 Antibody (ABIN967808) Images back to top
Antigen
Alternative Name Stat3 (STAT3 Antibody Abstract)
Background The Stat proteins function as both cytoplasmic signal transducers and activators of transcription. Stat91/84 (the two proteins are the result of alternate splicing-Stat91has an additional 38 C-terminal amino acids) and Stat113 were the first identified members of this protein family. With the discovery of additional members of the Stat family (Stats3 & 4), the nomenclature has been revised to indicate the Stat family members in the order of their discovery. Stat 91, 84, and 113 have become Stat1alpha, Stat1beta, and Stat2, respectively. Stat3 is a 92 kDa protein that is activated as a DNA binding protein through tyrosine phosphorylation in response to treatment of cells with EGF and IL-6 but not with IFN-gamma. Stat3 is widely expressed and can bind to DNA in the absence of Stat1alpha or Stat2. Stat3 can bind to the sis-inducible element (SIE) site from the c-fos promoter. The site is similar to the GAS element that is present in IFN-gamma induced genes. It appears that Stat3 binds to DNA as a homodimer, but it is also capable of binding as a heterodimer with Stat1. With the isolation of Stat3 and the discovery of Stat4, it appears that the Stat family may contain many members, each with a characteristic tissue distribution and specific activating ligands.
Molecular Weight 92 kDa
Research Area Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-STAT3 Antibody Target Details STAT3 Handling References for anti-STAT3 Antibody (ABIN967808) Images back to top
Comment

Related Products: ABIN968533, ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details References for anti-STAT3 Antibody (ABIN967808) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20°C.

References for anti-STAT3 Antibody (ABIN967808)

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details Handling Images back to top
Product cited in:

Buitenhuis, Baltus, Lammers, Coffer, Koenderman: "Signal transducer and activator of transcription 5a (STAT5a) is required for eosinophil differentiation of human cord blood-derived CD34+ cells." in: Blood, Vol. 101, Issue 1, pp. 134-42, 2002

Kirito, Osawa, Morita, Shimizu, Yamamoto, Oda, Fujita, Tanaka, Nakajima, Miura, Ozawa, Komatsu: "A functional role of Stat3 in in vivo megakaryopoiesis." in: Blood, Vol. 99, Issue 9, pp. 3220-7, 2002

Hart, Robertson, Donoghue: "Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation." in: Molecular biology of the cell, Vol. 12, Issue 4, pp. 931-42, 2001

Nielsen, Svejgaard, Skov, Odum: "Interleukin-2 induces tyrosine phosphorylation and nuclear translocation of stat3 in human T lymphocytes." in: European journal of immunology, Vol. 24, Issue 12, pp. 3082-6, 1995

Zhong, Wen, Darnell: "Stat3 and Stat4: members of the family of signal transducers and activators of transcription." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 11, pp. 4806-10, 1994

Images

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Supplier Images
Western Blotting (WB) image for anti-STAT3 antibody (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor)) (AA 1-175) (ABIN967808) Western blot analysis of Stat3 on a A431 cell lysate (Human epithelial carcinoma, ATC...