anti-Zebrafish (Danio rerio) STAT3 antibody for Western Blotting

Recommended STAT3 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
  • 1110034C02Rik
  • AW109958
  • Aprf
  • APRF
  • HIES
  • Xstat3
  • aprf
  • hies
  • stat3
  • wu:fc15d02
  • wu:fl59g06
  • z-Stat3
  • signal transducer and activator of transcription 3 (acute-phase response factor)
  • signal transduction and activation of transcription 3
  • signal transducer and activator of transcription 3
  • signal transducer and activator of transcription 3 (acute-phase response factor), gene 1
  • STAT3
  • stat3
  • Stat3
  • stat3.1
Epitope
AA 703-714, pTyr708, pTyr705
124
107
76
18
17
17
16
16
15
13
11
6
6
5
5
5
5
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Zebrafish (Danio rerio)
606
351
275
40
37
33
29
16
11
10
7
5
5
5
4
3
3
2
1
1
1
1
Host
Mouse
477
135
34
5
2
1
Clonality
Monoclonal
Conjugate
This STAT3 antibody is un-conjugated
28
24
19
14
12
11
9
6
4
4
4
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Western Blotting (WB)
555
244
228
91
85
84
62
55
27
12
12
9
8
6
5
3
3
3
2
2
2
2
2
1
1
1
1
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Catalog No. ABIN1449165
$ 308.00
Plus shipping costs $45.00

General

Antigen Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
Epitope AA 703-714, pTyr708, pTyr705
(124), (107), (76), (18), (17), (17), (16), (16), (15), (13), (11), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Zebrafish (Danio rerio)
(606), (351), (275), (40), (37), (33), (29), (16), (11), (10), (7), (5), (5), (5), (4), (3), (3), (2), (1), (1), (1), (1)
Host Mouse
(477), (135), (34), (5), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This STAT3 antibody is un-conjugated
(28), (24), (19), (14), (12), (11), (9), (6), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(555), (244), (228), (91), (85), (84), (62), (55), (27), (12), (12), (9), (8), (6), (5), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-STAT3 Antibody

Target Details STAT3 Application Details Handling References for anti-STAT3 antibody (ABIN1449165) Images
Sequence CVTQPpYLKT KFI
Specificity This antibody reacts with human and mouse STAT3 phosphorylated at Tyr705, and zebrafish STAT3 phosphorylated at Tyr708.
Purification Protein-A Sepharose
Immunogen 12 amino acids peptide (a.a. 703~714) which contained the phosphorylated Tyr708 of zebrafish STAT3
Clone PS3-1
Isotype IgG1

Target Details STAT3

Product Details anti-STAT3 Antibody Application Details Handling References for anti-STAT3 antibody (ABIN1449165) Images back to top
Antigen
Alternative Name STAT3 (STAT3 Antibody Abstract)
Background STAT (Signal Transducers and Activators of Transcription) proteins play important roles in development, cell differentiation, and cell cycle control. STAT3 is an ~85 kDa protein involved in the signaling pathways of many cytokines and growth factors, including GCSF and IL-6, where it functions as a negative regulator of transcription. STAT3 is also constitutively activated in a number of human tumors and it possesses anti-apoptotic activity and oncogenic potential. STAT3 may also regulate apoptosis by inhibiting NF?B. Activation of STAT3 by tyrosine phosphorylation results in dimerization, nuclear translocation, and DNA binding.Synonyms: APRF, Acute-phase response factor, STAT-3, Signal transducer and activator of transcription 3
Gene ID 6774
NCBI Accession NP_003141
UniProt P40763
Research Area Embryogenesis, Embryonic stem cells, Transcription Factors, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor

Application Details

Product Details anti-STAT3 Antibody Target Details STAT3 Handling References for anti-STAT3 antibody (ABIN1449165) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details References for anti-STAT3 antibody (ABIN1449165) Images back to top
Concentration 1.0 mg/mL
Buffer PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-STAT3 antibody (ABIN1449165)

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details Handling Images back to top
Background publications

Yamashita, Miyagi, Carmany-Rampey, Shimizu, Fujii, Schier, Hirano: "Stat3 Controls Cell Movements during Zebrafish Gastrulation." in: Developmental cell, Vol. 2, Issue 3, pp. 363-75, 2002

Images

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details Handling References for anti-STAT3 antibody (ABIN1449165) back to top
Supplier Images
Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 703-714), (pTyr705), (pTyr708) antibody (ABIN1449165) anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 703-714), (pTyr705), (pTyr708) antibody