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Browse our anti-ODF2 (ODF2) Antibodies

Full name:
anti-Outer Dense Fiber of Sperm Tails 2 Antibodies (ODF2)
On www.antibodies-online.com are 75 Outer Dense Fiber of Sperm Tails 2 (ODF2) Antibodies from 13 different suppliers available. Additionally we are shipping ODF2 Proteins (5) and many more products for this protein. A total of 85 ODF2 products are currently listed.
Synonyms:
AI848335, CT134, DKFZp469J0214, MMTEST29, ODF2/1, ODF2/2, ODF84, si:dkey-228b2.4

Most Popular Reactivities for anti-ODF2 (ODF2) Antibodies

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anti-Human ODF2 Antibodies:

anti-Mouse (Murine) ODF2 Antibodies:

anti-Rat (Rattus) ODF2 Antibodies:

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Top referenced anti-ODF2 Antibodies

  1. Human Polyclonal ODF2 Primary Antibody for IHC, IHC (p) - ABIN4341347 : Asante, Maccarthy-Morrogh, Townley, Weiss, Katayama, Palmer, Suzuki, Westlake, Stephens: A role for the Golgi matrix protein giantin in ciliogenesis through control of the localization of dynein-2. in Journal of cell science 2013 (PubMed)
    Show all 3 references for ABIN4341347

  2. Chimpanzee Polyclonal ODF2 Primary Antibody for EIA, WB - ABIN401415 : Soung, Kang, Kim, Kamijo, Yoon, Seong, Kuo, Miki, Kim, Kuriyama, Giam, Ahn, Lee: Requirement of hCenexin for proper mitotic functions of polo-like kinase 1 at the centrosomes. in Molecular and cellular biology 2006 (PubMed)
    Show all 2 references for ABIN401415

  3. Human Monoclonal ODF2 Primary Antibody for IF, ELISA - ABIN518506 : Xu, Zhang, Xiong, Huang, Salisbury, Hu, Ling: PIPKI? targets to the centrosome and restrains centriole duplication. in Journal of cell science 2014 (PubMed)

More Antibodies against ODF2 Interaction Partners

Human Outer Dense Fiber of Sperm Tails 2 (ODF2) interaction partners

  1. Cenexin controls centrosome positioning during cell migration by modulating microtubule organization and stability.Cenexin is required for spindle orientation.

  2. Cby (show CBY1 Antibodies) plays an important role in organization of both primary and motile cilia in collaboration with Cnx (show CANX Antibodies).

  3. Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 (show ODF1 Antibodies) and ninein (show NIN Antibodies).

  4. Cdk5 in the centriolar appendages mediates cenexin1 localization and primary cilia formation.

  5. Mouse and rat ODF2 (show ODF1 Antibodies) protein homolog sequences and expression are compared.

  6. We propose that hCenexin1 is a critical centrosomal component whose C-terminal extension is required for proper recruitment of Plk1 (show PLK1 Antibodies) and other components crucial for normal mitosis.

  7. A splice variant of hODF2 called hCenexin1, but not hODF2 itself, efficiently localizes to somatic centrosomes via a variant-specific C-terminal extension and recruits Plk1 (show PLK1 Antibodies) through a Cdc2 (show CDK1 Antibodies)-dependent phospho-S796 motif within the extension.

Mouse (Murine) Outer Dense Fiber of Sperm Tails 2 (ODF2) interaction partners

  1. Pax6 (show PAX6 Antibodies) directly regulates the activity of the Odf2 gene encoding for the appendage-specific protein Odf2 with a role for the assembly of mother centriole.

  2. The presence of multiple splicing variants hints that the function of Odf2 is diversified in such a way that each variant has a distinct role in the complex cellular and developmental processes.

  3. In adult mice, Odf2 expression was marked in the interdental cells, Boettcher cells, the root cells and root cell processes. Fainter expression was also visible in the hair cells of the maculae and cristae

  4. C-terminal region of Odf2 in mice is sufficient for ciliogenesis, the resulting basal bodies lack basal feet; loss of basal feet in ciliated epithelia disrupts polarized organization of apical microtubule lattice without affecting planar cell polarity.

  5. Results document the possible impact of loss of one Odf2 allele on sperm tail structure and function, resulting in a novel sperm tail phenotype.

  6. Odf2 contributes to assorted ciliopathies

  7. Odf2 is indispensable for the formation of distal/subdistal appendages and the generation of primary cilia, but not for other cell-cycle-related centriolar functions.

  8. Knockout of the abundant sperm tail protein (show SPAG4 Antibodies), outer dense fiber 2, results in preimplantation lethality.

  9. ODF2 is the main isoform in testicular tissue RT-PCR analyses revealed that isoforms are not restricted to specific tissues

  10. findings show that testicular expression of Odf2 correlates with spermiogenesis and ongoing sperm tail formation thus implicating functional differences between ODF2 and Cenexin.

ODF2 Antigen Profile

Antigen Summary

The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Alternative splicing results in multiple transcript variants. The longer transcripts, also known as 'Cenexins', encode proteins with a C-terminal extension that are differentially targeted to somatic centrioles and thought to be crucial for the formation of microtubule organizing centers.

Alternative names and synonyms associated with ODF2

  • outer dense fiber of sperm tails 2 (ODF2) antibody
  • outer dense fiber of sperm tails 2 (odf2) antibody
  • outer dense fiber of sperm tails 2 (Odf2) antibody
  • AI848335 antibody
  • CT134 antibody
  • DKFZp469J0214 antibody
  • MMTEST29 antibody
  • ODF2/1 antibody
  • ODF2/2 antibody
  • ODF84 antibody
  • si:dkey-228b2.4 antibody

Protein level used designations for ODF2

outer dense fiber of sperm tails 2 , outer dense fiber protein 2 , cenexin , outer dense fiber of sperm tails protein 2 , cancer/testis antigen 134 , cenexin 1 , outer dense fiber of sperm tails, 84-kD , sperm tail structural protein , 84 kDa outer dense fiber protein , outer dense fiber of sperm tail 2 , sperm outer dense fiber major protein 2 , testis-specific autoantigen

GENE ID SPECIES
100070205 Equus caballus
100125786 Xenopus (Silurana) tropicalis
100173182 Pongo abelii
4957 Homo sapiens
792921 Danio rerio
496006 Xenopus laevis
417213 Gallus gallus
491315 Canis lupus familiaris
100156735 Sus scrofa
539043 Bos taurus
18286 Mus musculus
29479 Rattus norvegicus
464769 Pan troglodytes
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