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anti-Mouse (Murine) GJA1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended GJA1 Antibody (supplied by: Log in to see )

Antigen
Gap Junction Protein, alpha 1, 43kDa (GJA1) Antibodies
  • cx43
  • gjal
  • oddd
  • dfnb38
  • connexin43
  • cx43a1
  • gja1
  • zfCx43.3
  • AU042049
  • AW546267
  • Cnx43
  • Cx43
  • Cx43alpha1
  • Gja-1
  • Npm1
  • AVSD3
  • CX43
  • DFNB38
  • GJAL
  • HLHS1
  • HSS
  • ODDD
  • connexin 43
  • gja1-A
  • Cnx46
  • Cx46
  • Gja-3
  • AI118175
  • Cnx32
  • Cx32
  • Gjb-1
  • gap junction protein, alpha 1, 43kDa
  • connexin 43
  • CONNEXIN 43 protein
  • connexin 43-like
  • gap junction protein, alpha 1
  • gap junction protein, alpha 3
  • gap junction protein, beta 1
  • gja1
  • cx43
  • CX43
  • CONNEXIN 43
  • LOC100359132
  • Gja1
  • GJA1
  • Gja3
  • Gjb1
Epitope
pSer367
66
21
20
15
15
12
10
8
7
7
6
6
6
5
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
257
195
175
56
25
22
22
20
18
17
10
10
7
7
7
5
4
4
4
3
3
3
3
2
2
1
1
1
Host
Rabbit
254
27
23
Clonality
Polyclonal
Conjugate
This GJA1 antibody is un-conjugated
5
5
4
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
238
121
104
72
43
19
14
13
12
7
7
5
2
2
Supplier
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Catalog No. ABIN498754
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.931439 ABIN1107367 IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
12.931439 ABIN784045 IHC (p) WB Rabbit IgG Cytoplasmic Domain Log in to see Polyclonal
12.931439 ABIN498634 IHC (p) WB Rabbit Log in to see Polyclonal
12.931439 ABIN214048 IHC (p) WB Rabbit IgG Ser367 Log in to see Polyclonal
12.931439 ABIN213629 IHC (p) Rabbit C-Term Log in to see Polyclonal
12.931439 ABIN4300011 IHC (p) Rabbit C-Term Log in to see Polyclonal
12.931439 ABIN451491 ICC IF IHC (p) IHC WB Rabbit Log in to see Polyclonal
1 ABIN197506 IHC (p) WB Rabbit AA 365-369 Log in to see Polyclonal 2
1 ABIN197018 IHC (p) WB Rabbit pSer367, pSer368 Log in to see Polyclonal 2
1 ABIN671451 IF (p) IHC (p) WB Rabbit IgG AA 232-282 Log in to see Polyclonal 2
1 ABIN265368 EIA IF IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN302928 IHC (p) WB Rabbit IgG pSer368 Log in to see Polyclonal
1 ABIN373332 IHC (p) WB Rabbit Cytoplasmic Domain Log in to see Polyclonal
1 ABIN2888387 IHC (p) ELISA WB Rabbit IgG pSer367 Log in to see Polyclonal
1 ABIN625908 IHC (p) WB Rabbit IgG 3rd Cytoplasmic Domain Log in to see Polyclonal
1 ABIN2878983 IF IHC (p) ELISA WB Rabbit IgG AA 333-382 Log in to see Polyclonal
1 ABIN4300010 IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN1734704 IHC (p) WB Rabbit IgG 3rd Cytoplasmic Domain Log in to see Polyclonal
1 ABIN1734708 IF IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1734707 IHC (p) WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-GJA1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-GJA1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 5 Antibodies 4 Antibodies 4 Antibodies
Western Blotting (WB) 151 Antibodies 170 Antibodies 193 Antibodies
Immunoprecipitation (IP) 9 Antibodies 9 Antibodies 10 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 73 Antibodies 45 Antibodies 46 Antibodies
Immunohistochemistry (IHC) 111 Antibodies 62 Antibodies

General

Antigen Gap Junction Protein, alpha 1, 43kDa (GJA1) Antibodies
Epitope pSer367
(66), (21), (20), (15), (15), (12), (10), (8), (7), (7), (6), (6), (6), (5), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(257), (195), (175), (56), (25), (22), (22), (20), (18), (17), (10), (10), (7), (7), (7), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Host Rabbit
(254), (27), (23)
Clonality
Polyclonal
Conjugate This GJA1 antibody is un-conjugated
(5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(238), (121), (104), (72), (43), (19), (14), (13), (12), (7), (7), (5), (2), (2)
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Product Details anti-GJA1 Antibody

Target Details GJA1 Application Details Handling Images
Specificity This antibody detects endogenous levels of Connexin 43 protein when phosphorylated at Ser367.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details GJA1

Product Details anti-GJA1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name GJA1 / Cx43 (GJA1 Antibody Abstract)
Background The connexins are a group of GAP junction proteins, which form a hexamer to compose a connexon. Clusters of connexons form a GAP junction through which low molecular weight proteins may diffuse from cell to cell. Several mammalian cells with malignant phenotypes exhibit decreased connexin expression and GAP junction communication. There is a decrease in GAP junctional communication in Src transformed cells. The decreased communication appears to be associated with tyrosine phosphorylation of connexin 43. Activated c-Src phosphorylates the C-terminal tail of connexin 43 on residue Tyr 265, resulting in a stable interaction between both proteins leading to inhibition of GAP junctional communication. In addition to tyrosine phosphorylation, connexin 43 has also been shown to be phosphorylated on serine in the absence of Src kinases and on both serine and tyrosine in cells expressing Src kinases such as pp60v-Src and/or c-Src.Synonyms: Connexin-43, GJAL, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein
Molecular Weight approx. 43 kDa
Gene ID 2697
NCBI Accession NP_000156
UniProt P17302
Pathways MAPK Signaling, Myometrial Relaxation and Contraction

Application Details

Product Details anti-GJA1 Antibody Target Details GJA1 Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-GJA1 Antibody Target Details GJA1 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-GJA1 Antibody Target Details GJA1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-GJA1 antibody (Gap Junction Protein, alpha 1, 43kDa) (pSer367) (ABIN498754) Immunohistochemistry (IHC) analyzes of p-Connexin 43 antibody in paraffin-embe...
Western Blotting (WB) image for anti-GJA1 antibody (Gap Junction Protein, alpha 1, 43kDa) (pSer367) (ABIN498754) Western blot (WB) analyzes of p-Connexin 43 antibody in extracts fro...