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|Application / Reactivity||Mouse (Murine)||Human|
|ELISA||13 Antibodies||45 Antibodies|
|Enzyme Immunoassay (EIA)||1 Antibodies||3 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||22 Antibodies||22 Antibodies|
|Immunohistochemistry (IHC)||18 Antibodies||35 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||9 Antibodies||13 Antibodies|
|Western Blotting (WB)||32 Antibodies|
|Immunochromatography (IC)||1 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies|
|Immunofluorescence (IF)||5 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunoprecipitation (IP)||4 Antibodies|
|Proximity Ligation Assay (PLA)||1 Antibodies|
|RNA Interference (RNAi)||2 Antibodies|
|Antigen||Mitogen-Activated Protein Kinase 11 (MAPK11) Antibodies|
|Epitope||Middle Region Alternatives|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This MAPK11 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-MAPK11 AntibodyTarget Details MAPK11 Application Details Handling References for anti-MAPK11 Antibody (ABIN359418) Images
|Specificity||This antibody detects MAPK11 at center.|
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human MAPK11.|
Target Details MAPK11Product Details anti-MAPK11 Antibody Application Details Handling References for anti-MAPK11 Antibody (ABIN359418) Images back to top
|Alternative Name||MAP Kinase p38 beta / MAPK11 (MAPK11 Antibody Abstract)|
|Background||MAPK11 is a Ser/Thr kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. It preferentially phosphorylates transcription factor ATF2. This protein is activated by phosphorylation on threonine and tyrosine by MKK6, and is inhibited by pyridinyl-imidazole related compounds. Highest expression levels are in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.Synonyms: Mitogen-activated protein kinase 11, PRKM11, SAPK2, Stress-activated protein kinase 2, p38-2|
|Molecular Weight||42132 Da|
|Gene ID||5600, 5874|
|Pathways||MAPK Signaling, Neurotrophin Signaling Pathway|
Application DetailsProduct Details anti-MAPK11 Antibody Target Details MAPK11 Handling References for anti-MAPK11 Antibody (ABIN359418) Images back to top
ELISA 1: 1,000Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-MAPK11 Antibody Target Details MAPK11 Application Details References for anti-MAPK11 Antibody (ABIN359418) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.|
References for anti-MAPK11 Antibody (ABIN359418)Product Details anti-MAPK11 Antibody Target Details MAPK11 Application Details Handling Images back to top
Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).
Dunham, Shimizu, Roe et al.: "The DNA sequence of human chromosome 22. ..." in: Nature, Vol. 402, Issue 6761, pp. 489-95, 1999 (PubMed).
Enslen, Raingeaud, Davis: "Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6." in: The Journal of biological chemistry, Vol. 273, Issue 3, pp. 1741-8, 1998 (PubMed).
Stein, Yang, Young et al.: "p38-2, a novel mitogen-activated protein kinase with distinct properties." in: The Journal of biological chemistry, Vol. 272, Issue 31, pp. 19509-17, 1997 (PubMed).
Kumar, McDonnell, Gum et al.: "Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 533-8, 1997 (PubMed).
ImagesProduct Details anti-MAPK11 Antibody Target Details MAPK11 Application Details Handling References for anti-MAPK11 Antibody (ABIN359418) back to top