anti-Mouse (Murine) MAPK9 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MAPK9 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase 9 (MAPK9) Antibodies
  • MAPK9
  • JNK-55
  • JNK2
  • JNK2A
  • JNK2ALPHA
  • JNK2B
  • JNK2BETA
  • PRKM9
  • SAPK
  • SAPK1a
  • p54a
  • p54aSAPK
  • AI851083
  • Prkm9
  • JNK2-ALPHA1
  • MAP kinase 9
  • mitogen-activated protein kinase 9
  • MAPK9
  • Mapk9
  • MPK9
Reactivity
Human, Mouse (Murine)
188
80
62
19
11
8
7
5
4
3
2
2
2
2
1
1
1
1
Host
Rabbit
119
42
22
4
1
Clonality
Monoclonal
Conjugate
This MAPK9 antibody is un-conjugated
6
5
3
3
3
3
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
175
91
60
42
28
20
9
7
7
2
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN5557375
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN658367 IHC (p) WB Rabbit Ig AA 206-233, Center Log in to see Polyclonal
1 ABIN1498927 IF IHC (p) WB Mouse IgG1 Log in to see 2G3
1 ABIN1498928 IF IHC (p) WB Mouse IgG1 Log in to see 4D1
1 ABIN1498930 IHC (p) WB Mouse IgG1 Log in to see 2D11
1 ABIN1498929 IF IHC (p) WB Mouse IgG1 Log in to see 1A1
1 ABIN2625189 ELISA IHC (p) WB Goat AA 217-230 Log in to see Polyclonal
1 ABIN5533806 IHC (p) WB Rabbit Ig Fraction AA 206-233 Log in to see Polyclonal
1 ABIN1912037 IHC (p) WB Rabbit AA 181-185 Log in to see Polyclonal
1 ABIN2742764 IHC (p) WB Rabbit Internal Region Log in to see Polyclonal
1 ABIN224077 IHC (p) WB Rabbit IgG pThr183 Log in to see Polyclonal
1 ABIN2963394 IHC (p) ELISA WB Goat AA 217-230, Internal Region Log in to see Polyclonal
1 ABIN1811596 IHC (p) WB Rabbit AA 206-233 Log in to see Polyclonal

Similar anti-MAPK9 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 31 Antibodies 91 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies 7 Antibodies
Immunocytochemistry (ICC) 6 Antibodies 9 Antibodies
Immunofluorescence (IF) 13 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 1 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunohistochemistry (IHC) 29 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies
Immunoprecipitation (IP) 10 Antibodies
Western Blotting (WB) 78 Antibodies
ELISA (Capture) 1 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunochromatography (IC) 1 Antibodies

General

Antigen Mitogen-Activated Protein Kinase 9 (MAPK9) Antibodies
Reactivity Human, Mouse (Murine)
(188), (80), (62), (19), (11), (8), (7), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(119), (42), (22), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MAPK9 antibody is un-conjugated
(6), (5), (3), (3), (3), (3)
Application Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(175), (91), (60), (42), (28), (20), (9), (7), (7), (2), (1), (1), (1), (1), (1)
Supplier Log in to see

Product Details anti-MAPK9 Antibody

Target Details MAPK9 Application Details Handling Images
Purification Purified by Protein A.
Immunogen Recombinant human JNK2 protein, around C-terminal 150aa.
Clone 1C7
Isotype IgG

Target Details MAPK9

Product Details anti-MAPK9 Antibody Application Details Handling Images back to top
Antigen
Alternative Name JNK2 (MAPK9 Antibody Abstract)
Background

Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK9/JNK2. In turn, MAPK9/JNK2 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. In response to oxidative or ribotoxic stresses, inhibits rRNA synthesis by phosphorylating and inactivating the RNA polymerase 1-specific transcription initiation factor RRN3. Promotes stressed cell apoptosis by phosphorylating key regulatory factors including TP53 and YAP1. In T-cells, MAPK8 and MAPK9 are required for polarized differentiation of T-helper cells into Th1 cells. Upon T-cell receptor (TCR) stimulation, is activated by CARMA1, BCL10, MAP2K7 and MAP3K7/TAK1 to regulate JUN protein levels. Plays an important role in the osmotic stress-induced epithelial tight-junctions disruption. When activated, promotes beta-catenin/CTNNB1 degradation and inhibits the canonical Wnt signaling pathway. Participates also in neurite growth in spiral ganglion neurons. MAPK9 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to JUN, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.

Synonyms: JNK2, SAPK, p54a, JNK2A, JNK2B, PRKM9, JNK-55, SAPK1a, JNK2BETA, p54aSAPK, JNK2ALPHA, Mitogen-activated protein kinase 9, MAP kinase 9, MAPK 9, Stress-activated protein kinase 1a, Stress-activated protein kinase JNK2, c-Jun N-terminal kinase 2, MAPK9

Gene ID 5601
UniProt P45984
Research Area Immunology, Innate Immunity
Pathways MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, Toll-Like Receptors Cascades

Application Details

Product Details anti-MAPK9 Antibody Target Details MAPK9 Handling Images back to top
Application Notes WB 1:1000-5000
IHC-P(50-200)
IF(ICC) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-MAPK9 Antibody Target Details MAPK9 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-MAPK9 Antibody Target Details MAPK9 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-MAPK9 antibody (Mitogen-Activated Protein Kinase 9) (ABIN5557375) SHG-44 lysates probed with JNK2 (1C7) Monoclonal Antibody at 1:1000 overnight at 4˚C...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-MAPK9 antibody (Mitogen-Activated Protein Kinase 9) (ABIN5557375) SHG-44 cells were stained with JNK2 (1C7) Monoclonal Antibody at [1:200] incubated o...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-MAPK9 antibody (Mitogen-Activated Protein Kinase 9) (ABIN5557375) HeLa cells were stained with JNK2 (1C7) Monoclonal Antibody at [1:200] incubated ove...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MAPK9 antibody (Mitogen-Activated Protein Kinase 9) (ABIN5557375) Paraformaldehyde-fixed, paraffin embedded mouse brain tissue, Antigen retrieval by bo...