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Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 ELISA Kits (RPS6KA1)
On are 10 Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) ELISA Kits from 6 different suppliers available. Additionally we are shipping RPS6KA1 Antibodies (393) and RPS6KA1 Proteins (12) and many more products for this protein. A total of 426 RPS6KA1 products are currently listed.
CLS, hu-1, HU-3, ISPK-1, mapkapk1a, MAPKAPK1B, MRX19, p90-RSK2, p90rsk, pp90RSK2, RPS6KA, RSK, rsk1, RSK2, S6K-alpha3
list all ELISA KIts Gene Name GeneID UniProt
RPS6KA1 20111  
RPS6KA1 81771 Q63531
RPS6KA1 6195 Q15418

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Mouse (Murine) Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) interaction partners

  1. In hippocampal neurons of wild-type mice, pP90RSK translocates into the nucleus upon stimulation with forskolin (left), whereas in Period1-knockout (Per1 (show PER1 ELISA Kits)(-/-) ) mice (right) the kinase is trapped at the nuclear periphery

  2. Data show that the phosphoinositide-dependent kinase 1 (PDK1 (show PDPK1 ELISA Kits))-p90 (show GPAM ELISA Kits) kDa ribosomal S6 kinases (Rsks) Rsk1/2 pathway is critical for establishment and maintenance of a normal Langerhans cells (LC) network.

  3. IL-6 (show IL6 ELISA Kits) induces the activation of the Stat3 (show STAT3 ELISA Kits) signaling and promotes the downmodulation of the p90RSK/eEF2 (show EEF2 ELISA Kits) and mTOR (show FRAP1 ELISA Kits)/p70S6K (show RPS6KB1 ELISA Kits) axes, while it does not affect the activation of AKT (show AKT1 ELISA Kits).

  4. analysis of p38 (show CRK ELISA Kits)-MK2 (show KCNA2 ELISA Kits)-activated Rsk signaling in toll (show TLR4 ELISA Kits)-like receptor-stimulated dendritic cells

  5. These data indicate that aripiprazole and quetiapine signal to specific nuclear targets of ERK (show EPHB2 ELISA Kits), which for quetiapine occurs via an EGFR (show EGFR ELISA Kits)-linked mechanism, possibly indicating involvement of this system in its action.

  6. hypoxia/reoxygenation (H/R)-mediated decrease in PKARIalpha protein levels leads to activation of RSK1, which via phosphorylation of NHE1 (show SLC9A1 ELISA Kits) induces cardiomyocyte apoptosis.

  7. RSK1 Cys223 glutathionylation may contribute to regulate the levels of nitric in the brain.

  8. Our study highlights the importance of the p90RSK/ERK5 (show MAPK7 ELISA Kits) module as a critical mediator of endothelial dysfunction in diabetes mellitus and atherosclerosis formation.

  9. Results show increased protein levels of Rsk1 and Rsk2 (show RPS6KA3 ELISA Kits) in the striatum of Huntington disease (show HTT ELISA Kits) mice and and striatal cells transfected with full-length mutant Huntingtin (show HTT ELISA Kits).

  10. Type I keratin (show KRT12 ELISA Kits) 17 (show KRT17 ELISA Kits) protein is phosphorylated on serine 44 by p90 (show GPAM ELISA Kits) ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion

Human Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) interaction partners

  1. Inhibition of RSK2 (show RPS6KA3 ELISA Kits) was used to investigate the function of RSK2 (show RPS6KA3 ELISA Kits) on PDK1 (show PDK1 ELISA Kits)-induced inflammation. The phosphorylation of RSK2 (show RPS6KA3 ELISA Kits) was detected when PDK1 (show PDK1 ELISA Kits) was inhibited. Inhibition of RSK2 (show RPS6KA3 ELISA Kits) reduced the PDK1 (show PDK1 ELISA Kits)-induced cell invasion and cytokines secretion in human rheumatoid arthritis synovial MH7A cells. In response to TNF-alpha (show TNF ELISA Kits), PDK1 (show PDK1 ELISA Kits) could phosphorylate RSK2 (show RPS6KA3 ELISA Kits) and activated RSK2 (show RPS6KA3 ELISA Kits), then promoting the activation of NF-kappaB (show NFKB1 ELISA Kits).

  2. Our finding demonstrates that RSK2 (show RPS6KA3 ELISA Kits) directly phosphorylates stathmin (show STMN1 ELISA Kits) and regulates microtubule polymerization to provide a pro-invasive and pro-metastatic advantage to cancer cells. Therefore, the RSK2 (show RPS6KA3 ELISA Kits)-stathmin (show STMN1 ELISA Kits) pathway represents a promising therapeutic target and a prognostic marker for metastatic human cancers.

  3. Data suggest that UBR5 (show UBR5 ELISA Kits) down-regulates levels of TRAF3 (show TRAF3 ELISA Kits), a key component of Toll (show TLR4 ELISA Kits)-like receptor signaling, via the miRNA pathway; p90RSK is an upstream regulator of UBR5 (show UBR5 ELISA Kits); p90RSK phosphorylates UBR5 (show UBR5 ELISA Kits) as required for translational repression of TRAF3 (show TRAF3 ELISA Kits) mRNA. (UBR5 (show UBR5 ELISA Kits) = ubiquitin protein ligase E3 component n-recognin 5 (show UBR5 ELISA Kits) protein; TRAF3 (show TRAF3 ELISA Kits) = TNF receptor-associated factor 3 (show TRAF3 ELISA Kits); p90RSK = 90 kDa ribosomal protein S6 (show RPS6 ELISA Kits) kinase (show RPS6KB1 ELISA Kits))

  4. Data indicate that BTG2 (show BTG2 ELISA Kits), MAP3K11 (show MAP3K11 ELISA Kits), RPS6KA1 and PRDM1 (show PRDM1 ELISA Kits) as putative targets of microRNA miR (show MLXIP ELISA Kits)-125b.

  5. VEGF-A (show VEGFA ELISA Kits) driven Mdm2 (show MDM2 ELISA Kits) phosphorylation on Ser166 is dependent on the ERK1/2 (show MAPK1/3 ELISA Kits)/p90RSK signaling pathway in primary human endothelial cells.

  6. we discuss the function of the RSK2 (show RPS6KA3 ELISA Kits) signaling axis by interactions with binding partners in cancer development--{REVIEW}

  7. Results showed that RSK2 (show RPS6KA3 ELISA Kits) gene was overexpressed in osteosarcoma patients cells and its knockdown increased cell apoptosis, enhanced cell chemosensitivity, inhibits proliferation and migration, and weakened tumor formation.

  8. Upregulated expression of RSK2 (show RPS6KA3 ELISA Kits) is associated with breast cancer.

  9. The p90RSK has an essential role in promoting tumor growth and proliferation in non-small cell lung cancer (NSCLC). BID (show BID ELISA Kits) may serve as an alternative cancer treatment in NSCLC.

  10. RSK1 binds to EBP50 (show SLC9A3R1 ELISA Kits) at its first PDZ domain (show INADL ELISA Kits), and mitogen activated RSK1 phosphorylates EBP50 (show SLC9A3R1 ELISA Kits) at T156, an event that is crucial for its nuclear localization

RPS6KA1 Antigen Profile

Antigen Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Alternative names and synonyms associated with RPS6KA1

  • ribosomal protein S6 kinase polypeptide 1 (Rps6ka1) Elisa Kit
  • ribosomal protein S6 kinase, 90kDa, polypeptide 1 (RPS6KA1) Elisa Kit
  • ribosomal protein S6 kinase, 90kDa, polypeptide 1 (rps6ka1) Elisa Kit
  • ribosomal protein S6 kinase, 90kDa, polypeptide 3 (RPS6KA3) Elisa Kit
  • CLS Elisa Kit
  • hu-1 Elisa Kit
  • HU-3 Elisa Kit
  • ISPK-1 Elisa Kit
  • mapkapk1a Elisa Kit
  • MAPKAPK1B Elisa Kit
  • MRX19 Elisa Kit
  • p90-RSK2 Elisa Kit
  • p90rsk Elisa Kit
  • pp90RSK2 Elisa Kit
  • RPS6KA Elisa Kit
  • RSK Elisa Kit
  • rsk1 Elisa Kit
  • RSK2 Elisa Kit
  • S6K-alpha3 Elisa Kit

Protein level used designations for RPS6KA1

90 kDa ribosomal protein S6 kinase 1 , MAP kinase-activated protein kinase 1a , MAPK-activated protein kinase 1a , MAPKAP kinase 1a , MAPKAPK-1a , RSK-1 , S6K-alpha-1 , p90-RSK 1 , p90RSK1 , p90S6K , ribosomal S6 kinase 1 , ribosomal protein S6 kinase alpha-1 , ribosomal protein S6 kinase, 90kD, polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1 , MAPKAPK1A , S6 protein kinase (Rsk-1) , S6K-alpha 1 , pp90RSK1 , dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1) , ribosomal protein S6 kinase alpha 1 , MAP kinase-activated protein kinase 1 , MAPK-activated protein kinase 1 , MAPKAP kinase 1 , MAPKAPK-1 , S6KII-alpha , p90-RSK , ribosomal protein S6 kinase 2 alpha , ribosomal protein S6 kinase II alpha , P90-RSK , S6 kinase II beta , S6KII-beta , ribosomal protein S6 kinase 2 beta , ribosomal protein S6 kinase II beta , MAP kinase-activated protein kinase 1b , MAPK-activated protein kinase 1b , MAPKAP kinase 1b , MAPKAPK-1b , RSK-2 , S6K-alpha-3 , insulin-stimulated protein kinase 1 , p90-RSK 3 , ribosomal S6 kinase 2 , ribosomal protein S6 kinase alpha-3

20111 Mus musculus
81771 Rattus norvegicus
533908 Bos taurus
6195 Homo sapiens
386579 Gallus gallus
487353 Canis lupus familiaris
100057166 Equus caballus
100523972 Sus scrofa
445821 Xenopus laevis
6197 Homo sapiens
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