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anti-Mouse (Murine) SIRT1 antibody for Enzyme Immunoassay

Recommended SIRT1 Antibody (supplied by: Log in to see )

Antigen
Sirtuin 1 (SIRT1) Antibodies
  • AA673258
  • SIR2
  • Sir2
  • Sir2a
  • Sir2alpha
  • SIR2L1
  • sir2l1
  • sirtuin
  • sirtuin 1
Epitope
N-Term
30
21
20
17
16
16
13
13
10
5
4
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
252
103
45
8
8
6
4
4
3
3
2
2
2
2
1
1
Host
Chicken
183
57
25
6
2
Clonality
Polyclonal
Conjugate
This SIRT1 antibody is un-conjugated
14
12
9
5
5
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
212
112
57
42
41
34
28
25
11
5
4
4
3
2
1
1
Supplier
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Catalog No. ABIN783610
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008854274 ABIN615980 EIA IHC (p) WB Goat AA 577-590, Internal Region Log in to see Polyclonal

Top referenced anti-SIRT1 antibody for Enzyme Immunoassay

Similar anti-SIRT1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 204 Antibodies 68 Antibodies 33 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Immunoprecipitation (IP) 29 Antibodies 2 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 40 Antibodies 14 Antibodies 6 Antibodies
Immunohistochemistry (IHC) 58 Antibodies 15 Antibodies 8 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies 2 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 34 Antibodies 33 Antibodies 11 Antibodies
Immunofluorescence (IF) 43 Antibodies

General

Antigen Sirtuin 1 (SIRT1) Antibodies
Epitope N-Term
(30), (21), (20), (17), (16), (16), (13), (13), (10), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(252), (103), (45), (8), (8), (6), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1)
Host Chicken
(183), (57), (25), (6), (2)
Clonality
Polyclonal
Conjugate This SIRT1 antibody is un-conjugated
(14), (12), (9), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(212), (112), (57), (42), (41), (34), (28), (25), (11), (5), (4), (4), (3), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-SIRT1 Antibody

Target Details SIRT1 Application Details Handling References for anti-SIRT1 Antibody (ABIN783610) Images
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Affinity chromatography purified via peptide column
Immunogen 19 amino acid peptide near the amino terminus of human SIRT1

Target Details SIRT1

Product Details anti-SIRT1 Antibody Application Details Handling References for anti-SIRT1 Antibody (ABIN783610) Images back to top
Antigen
Alternative Name SIRT1 (SIRT1 Antibody Abstract)
Background The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT1 has the closest homology to the yeast Sir2p and is widely expressed in fetal and adult tissues. SIRT1 regulates the p53-dependent DNA damage response pathway by binding to and deacetylating p53, specifically via lysine residue.Synonyms: NAD-dependent deacetylase sirtuin-1, S. cerevisiae, SIR2-like protein 1, SIR2L1, SIR2alpha, SIRT-1, homolog) 1, sirtuin (silent mating type information regulation 2, sirtuin 1, sirtuin type 1, sirtuin-1
Gene ID 23411
NCBI Accession NP_001135970
UniProt Q96EB6
Research Area Chromatin and Nuclear Signaling, Apoptosis/Necrosis, Proteases
Pathways MAPK Signaling

Application Details

Product Details anti-SIRT1 Antibody Target Details SIRT1 Handling References for anti-SIRT1 Antibody (ABIN783610) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details References for anti-SIRT1 Antibody (ABIN783610) Images back to top
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C.

References for anti-SIRT1 Antibody (ABIN783610)

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details Handling Images back to top
Background publications

Afshar, Murnane: "Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2." in: Gene, Vol. 234, Issue 1, pp. 161-8, 1999