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Browse our Adrenocorticotropic hormone Proteins (ACTH)

Full name:
Adrenocorticotropic hormone Proteins (ACTH)
On www.antibodies-online.com are 6 Adrenocorticotropic hormone (ACTH) Proteins from 4 different suppliers available. Additionally we are shipping Adrenocorticotropic hormone Antibodies (424) and Adrenocorticotropic hormone Kits (97) and many more products for this protein. A total of 574 Adrenocorticotropic hormone products are currently listed.
Synonyms:
ACTH, alpha-MSH, alphaMSH, BE, Beta-LPH, beta-MSH, CLIP, Gamma-LPH, gamma-MSH, LPH, MSH, NPP, POC, Pomc-1, Pomc1
list all proteins Gene Name GeneID UniProt
ACTH 18976 P01193
ACTH 5443 P01189
ACTH    

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Adrenocorticotropic hormone Proteins (ACTH) by Origin

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Mouse (Murine) Adrenocorticotropic hormone (ACTH) interaction partners

  1. it is suggested that the suppression of NeuroD1 (show NEUROD1 Proteins) expression and the inhibition of NeuroD1 (show NEUROD1 Proteins)/E-box interaction may play an important role in the Gc-mediated negative regulation of Pomc (show POMC Proteins).

  2. To clarify the functional roles of the AKT-mTOR pathway in the hippocampal neurons, we generated conditional knockout mice harboring the deletion of Pten (Pten-cKO) in Proopiomelanocortin-expressing neurons.

  3. Epo (show EPO Proteins) regulates hypothalamus POMC (show POMC Proteins) expression via STAT3 (show STAT3 Proteins) activation.

  4. Data suggest that the solitary tract pro-opiomelanocortin (show POMC Proteins) (NTSPOMC) neurons were involved in cardiorespiratory control and endogenous analgesia.

  5. hypothalamic arcuate nucleus (Arc (show NOL3 Proteins))POMC (show POMC Proteins)-deficient mice, which develop severe obesity and insulin (show INS Proteins) resistance, unexpectedly exhibit improved glucose tolerance and remain protected from hyperglycemia via decreased renal GLUT2 (show SLC2A2 Proteins) expression and glycosuria.

  6. Hypomethylation of POMC (show POMC Proteins) promoter occurred in the hypothalamus of the high sucrose diet offspring compared with controls.

  7. Together, these results suggest that alpha-MSH alleviates Dex-induced damages to cultured osteoblasts through activating MC4R (show MC4R Proteins)-SphK1 (show SPHK1 Proteins) signaling.

  8. These data indicate that glucose induces distinct excitatory synaptic plasticity in different subpopulations of POMC (show POMC Proteins) neurons.

  9. Although genetic deletion of either Atg12 (show ATG12 Proteins) or Atg5 (show ATG5 Proteins) renders POMC (show POMC Proteins) neurons autophagy-deficient, mice lacking Atg5 (show ATG5 Proteins) in POMC (show POMC Proteins) neurons do not exhibit these phenotypes.

  10. Data indicate that LIM-homeodomain (show LHX2 Proteins) transcription factor Islet 1 (show ISL1 Proteins) is necessary for hypothalamic proopiomelanocortin (show POMC Proteins) gene (Pomc (show POMC Proteins)) expression during embryogenesis.

Human Adrenocorticotropic hormone (ACTH) interaction partners

  1. Data suggest that alpha-MSH enhances cell adhesion to fibronectin (show FN1 Proteins) in primary mixed synoviocytes obtained from osteoarthritis patients; alpha-MSH reduces secretion of cytokines (TNF (show TNF Proteins), IL-6 (show IL6 Proteins) and IL-8 (show IL8 Proteins)) in such synoviocyte cultures.

  2. Data suggest that the first screening step diagnosis for pituitary adenoma was determined based upon immunohistochemical (IHC) scores for Pit-1 (show POU1F1 Proteins), SF-1 (show NR5A1 Proteins), and ACTH (show POMC Proteins).

  3. The aim of this survey is to evaluate the association of genetic variants of melanocortin-4-receptor (MC4R (show MC4R Proteins)), pro-opiomelanocortin (POMC (show POMC Proteins)), apolipoprotein E (APOE (show APOE Proteins)) and agouti-related protein (AGRP (show AGRP Proteins)) with obesity in the North Indian population.

  4. The expression of Pomc (show POMC Proteins) mRNA was stimulated in the arcuate nucleus after skin exposure to UVB.

  5. hsa (show CD24 Proteins)-miR (show MLXIP Proteins)-34a can regulate the CRH (show CRH Proteins)/CRHR1 (show CRHR1 Proteins)/POMC (show POMC Proteins) axis and may influence body mass index.

  6. these common variants in PCSK1 (show PCSK1 Proteins) and POMC (show POMC Proteins) were not the major cause of obesity in the Thai subjects sampled. However, variants in PCSK1 (show PCSK1 Proteins) did affect cholesterol level, LDL-C level, and waist circumference.

  7. ACTH (show POMC Proteins) was readily detected at significantly higher levels in regions of ACTH (show POMC Proteins)-secreting adenomas and in normal anterior adenohypophysis compared with non-secreting adenoma and neurohypophysis.

  8. CSF (show CSF2 Proteins) POMC (show POMC Proteins) was higher in lean vs. overweight/obese subjects.

  9. There was a non-linear association between leukocyte telomere length and plasma ACTH (show POMC Proteins) after laboratory stressor in elderly adults.

  10. Synovial fluid alpha-MSH levels showed an independent and negative correlation with articular cartilage degeneration in patients with knee ACL (show ACLY Proteins) deficiency.

Cow (Bovine) Adrenocorticotropic hormone (ACTH) interaction partners

  1. The association has been reported between polymorphisms of the CRH (show CRH Proteins) and POMC (show POMC Proteins) genes with economic traits in Korean cattle.

  2. Expression of the hepatic endocannabinoid system and proopiomelanocortin (show POMC Proteins) was altered by plane of dietary energy prepartum particularly during the first 2-week postpartum.

  3. Significant associations were observed between POMC (show POMC Proteins) c.288C>T with start-of-finishing weight (SOF (show GJA1 Proteins) WT; P = 0.04), hot carcass weight (HCW; P = 0.02), average fat and grade fat (both P = 0.05), carcass rib-eye area (REA (show PHB2 Proteins); P = 0.03) and marbling

  4. The polymorphism of POMC (show POMC Proteins) gene is associated with the growth traits of Nanyang cattle.

Pig (Porcine) Adrenocorticotropic hormone (ACTH) interaction partners

  1. The expression of the genes coding for proopiomelanocortin (POMC (show POMC Proteins)), proenkephalin (PENK (show PENK Proteins)) and prodynorphin (PDYN (show PDYN Proteins)) in porcine luteal cells isolated from corpora lutea (CL) collected on days 3-6, 8-10 and 13-16 of the oestrous cycle is reported.

Adrenocorticotropic hormone (ACTH) Protein Profile

Protein Summary

This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.

Alternative names and synonyms associated with Adrenocorticotropic hormone (ACTH)

  • pro-opiomelanocortin-alpha (Pomc)
  • proopiomelanocortin (POMC)
  • ACTH protein
  • alpha-MSH protein
  • alphaMSH protein
  • BE protein
  • Beta-LPH protein
  • beta-MSH protein
  • CLIP protein
  • Gamma-LPH protein
  • gamma-MSH protein
  • LPH protein
  • MSH protein
  • NPP protein
  • POC protein
  • Pomc-1 protein
  • Pomc1 protein

Protein level used designations for ACTH

adrenal corticotropic hormone , adrenocorticotropic hormone , alpha-melanocyte stimulating hormone , beta-endorphin , corticotropin-like intermediary peptide , corticotropin-lipotropin , melanotropin gamma , met-enkephalin , pro-opiomelanocortin , adrenocorticotropin , alpha-MSH , alpha-melanocyte-stimulating hormone , beta-LPH , beta-MSH , beta-melanocyte-stimulating hormone , gamma-LPH , gamma-MSH , lipotropin beta , lipotropin gamma , melanotropin alpha , melanotropin beta , opiomelanocortin prepropeptide , pro-ACTH-endorphin , proopiomelanocortin preproprotein , proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin) , beta-lipotropin , beta-melanocyte stimulating hormone

GENE ID SPECIES
18976 Mus musculus
5443 Homo sapiens
403659 Canis lupus familiaris
281416 Bos taurus
396863 Sus scrofa
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