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Browse our Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 Proteins (CYP21A2)

Full name:
Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 Proteins (CYP21A2)
On www.antibodies-online.com are 31 Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) Proteins from 6 different suppliers available. Additionally we are shipping Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 Antibodies (77) and Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 Kits (9) and many more products for this protein. A total of 123 Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 products are currently listed.
Synonyms:
21-OH, 21-OHase, 21OH, 21OHA, 21OHB, CA21H, CAH1, CPS1, Cyp21, Cyp21-ps1, CYP21A, Cyp21a2-ps, Cyp21a2ps, CYP21B, CYP21OH-A, Oh21-1, Oh21-2, P450c21B
list all proteins Gene Name GeneID UniProt
CYP21A2 13079 P03940
CYP21A2 24298  
CYP21A2 1589 P08686

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Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 Proteins (CYP21A2) by Origin

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More Proteins for Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 Interaction Partners

Pig (Porcine) Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) interaction partners

  1. CYP21 gene polymorphisms were analyzed in association with litter size.

Mouse (Murine) Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) interaction partners

  1. Extra-adrenal induction of Cyp21a1 ameliorates steroid metabolism in 21-OHD mice. This study suggests a novel therapeutic strategy for congenital adrenal hyperplasia, which warrants further investigations.

Human Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) interaction partners

  1. spectrum of CYP21A2 mutations in Congenital Adrenal Hyperplasia in an Indian cohort

  2. CYP21A2 mutation spectrum of Chinese patients with 21-hydroxylase deficiency-induced congenital adrenal hyperplasia

  3. 27 CYP21A2 mutant alleles is identified in 14 congenital adrenal hyperplasia-suspected patients. The c.293-13A>G (or c.293-13C>G) was the most common mutation, and p.Ile173Asn was the second, identified in 25% and 17.9% of alleles.

  4. Data suggest that the definitive diagnosis can be established based on steroid profile (USP) and/or 21-hydroxylase (CYP21A2) genetic testing.

  5. In current study, molecular testing of 21 patients with classic form of Congenital adrenal hyperplasia identified eight mutations of the CYP21A2 gene.

  6. The results suggest that the A>G variation in the Z promoter is involved in misregulating the transcriptional activity of the CYP21A2 gene.

  7. Data suggest 3 siblings with nonclassical, congenital adrenal hyperplasia exhibit rare mutation in CYP21A2; siblings are heterozygotes for maternal 30 kb deletion and exhibit a second, rare point mutation (c.1097G>A, p.R366H) in exon 8. [CASE REPORT]

  8. Novel p.Leu129Pro and p.Ser165Pro CYP21A2 gene mutations in Serbian patients with congenital adrenal hyperplasia.

  9. The main conclusion from a mutation-structure-activity study is that the severity of the congenital adrenal hyperplasia clinical manifestations can be directly correlated with the degree of mutation-induced damage in terms of protein fold stability and active site changes in the structural model of Cytochrome P450 21A2.

  10. Increased allelic frequency for the CYP21A2 p.Asn493Ser polymorphism is observed in girls with premature adrenarche.

Cow (Bovine) Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) interaction partners

  1. The mRNA expression of P450Arom (show CYP19A1 Proteins) was detected using RT-PCR analysis in both hypothalamic and cortical primary cell cultures. P450Arom (show CYP19A1 Proteins) was identified in both neurons and astrocytes

Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene\; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2)

  • cytochrome P450, family 21, subfamily A, polypepide 2 (CYP21A2)
  • cytochrome P450, family 21, subfamily a, polypeptide 1 (Cyp21a1)
  • cytochrome P450, family 21, subfamily A, polypeptide 2 (CYP21A2)
  • cytochrome P450, subfamily XXI (steroid 21-hydroxylase) (CYP21)
  • cytochrome P450c21 (CYP21A2)
  • steroid 21-hydroxylase-like (LOC101094596)
  • 21-OH protein
  • 21-OHase protein
  • 21OH protein
  • 21OHA protein
  • 21OHB protein
  • CA21H protein
  • CAH1 protein
  • CPS1 protein
  • Cyp21 protein
  • Cyp21-ps1 protein
  • CYP21A protein
  • Cyp21a2-ps protein
  • Cyp21a2ps protein
  • CYP21B protein
  • CYP21OH-A protein
  • Oh21-1 protein
  • Oh21-2 protein
  • P450c21B protein

Protein level used designations for CYP21A2

21-OHase , FK506 binding protein like , cytochrome P-450c21 , cytochrome P450 21 , cytochrome P450 21-hydroxylase , cytochrome P450 XXI , cytochrome P450-C21 , steroid 21-hydroxylase , 21-hydroxylase , cytochrome P-450 , cytochrome P450 hydroxylase A , cytochrome P450, 21, pseudogene , cytochrome P450, 21, steroid 21 hydroxylase , cytochrome P450, family 21, subfamily a, polypeptide 2, pseudogene , steroid 21 hydroxylase , Cytochrome P450 subfamily XXI (steroid 21-hydroxylase) , P-450c21 , P450-C21 , cytochrome P450 21 steroid 21 hydroxylase , cytochrome P450, subfamily 21A, polypeptide 1 , cytochrome P450, subfamily XXI (steroid 21-hydroxylase) , cytochrome P450, subfamily XXIA (steroid 21-hydroxylase, congenital adrenal hyperplasia), polypeptide 2 , cytochrome P450-C21B , steroid 21-monooxygenase , cytochrome P450, family 21 , cytochrome P450, family 21, subfamily A , Cytochrome P-450c21 , Cytochrome P450 21 , Cytochrome P450 XXI , Cytochrome P450-C21

GENE ID SPECIES
403337 Sus scrofa
13079 Mus musculus
24298 Rattus norvegicus
1589 Homo sapiens
282425 Bos taurus
281741 Bos taurus
415124 Canis lupus familiaris
101094596 Felis catus
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