anti-Human CXCR7 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended CXCR7 Antibody (supplied by: Log in to see )

Antigen
Chemokine (C-X-C Motif) Receptor 7 (CXCR7) Antibodies
  • BEST:LD12308
  • CG3171
  • Dmel\\CG3171
  • LD12308
  • Tre-1
  • anon-WO0170980.16
  • anon-WO0170980.17
  • anon-WO0170981.1
  • sctt
  • tre-1
  • tre1
  • CMKOR1
  • CXC-R7
  • CXCR-7
  • CXCR7
  • GPR159
  • RDC-1
  • RDC1
  • AW541270
  • Cmkor1
  • Cxcr7
  • Rdc1
  • Trapped in endoderm 1
  • G protein coupled receptor
  • atypical chemokine receptor 3
  • chemokine (C-X-C motif) receptor 7
  • Tre1
  • MmrVgp88
  • ACKR3
  • Ackr3
  • Cxcr7
  • CXCR7
Epitope
AA 184-213
47
26
25
15
13
11
11
11
9
6
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
202
107
78
7
7
6
6
4
4
4
4
3
1
1
1
1
1
1
1
Host
Rabbit
132
82
19
5
1
Clonality
Polyclonal
Conjugate
This CXCR7 antibody is un-conjugated
14
12
10
10
10
10
9
9
8
8
7
7
6
4
4
2
2
2
2
2
2
2
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
131
97
54
40
26
25
16
7
5
5
3
3
2
2
1
Options
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Catalog No. ABIN1387536
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN741990 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN2812090 IF (p) Alexa Fluor 594 Rabbit IgG AA 312-362 Log in to see Polyclonal
1 ABIN1396949 IF (p) Alexa Fluor 647 Rabbit IgG AA 184-213 Log in to see Polyclonal
1 ABIN1396951 IF (p) FITC Rabbit IgG AA 184-213 Log in to see Polyclonal
1 ABIN1396946 IF (p) Alexa Fluor 350 Rabbit IgG AA 184-213 Log in to see Polyclonal
1 ABIN1396947 IF (p) Alexa Fluor 488 Rabbit IgG AA 184-213 Log in to see Polyclonal
1 ABIN1414822 IF (p) Cy3 Rabbit IgG AA 184-213 Log in to see Polyclonal
1 ABIN1414824 IF (p) Cy5.5 Rabbit IgG AA 184-213 Log in to see Polyclonal
1 ABIN1414825 IF (p) Cy7 Rabbit IgG AA 184-213 Log in to see Polyclonal
1 ABIN1414823 IF (p) Cy5 Rabbit IgG AA 184-213 Log in to see Polyclonal
1 ABIN1396948 IF (p) Alexa Fluor 555 Rabbit IgG AA 184-213 Log in to see Polyclonal
1 ABIN2808559 IF (p) Alexa Fluor 594 Rabbit IgG AA 184-213 Log in to see Polyclonal
1 ABIN741996 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN741994 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN741993 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
1 ABIN741995 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN741997 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN892842 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN892841 IF (p) Alexa Fluor 350 Rabbit IgG Log in to see Polyclonal
1 ABIN892843 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal

General

Antigen Chemokine (C-X-C Motif) Receptor 7 (CXCR7) Antibodies
Epitope AA 184-213
(47), (26), (25), (15), (13), (11), (11), (11), (9), (6), (5), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(202), (107), (78), (7), (7), (6), (6), (4), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(132), (82), (19), (5), (1)
Clonality
Polyclonal
Conjugate This CXCR7 antibody is un-conjugated
(14), (12), (10), (10), (10), (10), (9), (9), (8), (8), (7), (7), (6), (4), (4), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(131), (97), (54), (40), (26), (25), (16), (7), (5), (5), (3), (3), (2), (2), (1)
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Product Details anti-CXCR7 Antibody

Target Details CXCR7 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human CXCR7/RDC1
Isotype IgG

Target Details CXCR7

Product Details anti-CXCR7 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Cxcr7/Rdc1 (CXCR7 Antibody Abstract)
Background

Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.

Subcellular location: Extracellular

Synonyms: RDC1, CXCR7, RDC-1, CMKOR1, CXC-R7, CXCR-7, GPR159, Atypical chemokine receptor 3, C-X-C chemokine receptor type 7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, ACKR3

Gene ID 57007
UniProt P25106
Pathways Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling

Application Details

Product Details anti-CXCR7 Antibody Target Details CXCR7 Handling Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-CXCR7 Antibody Target Details CXCR7 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-CXCR7 Antibody Target Details CXCR7 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 184-213) antibody (ABIN1387536) Formalin-fixed and paraffin embedded rat brain labeled with Anti-CXCR7/RDC1 Polyclona...
Immunohistochemistry (IHC) image for anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 184-213) antibody (ABIN1387536) Formalin-fixed and paraffin embedded rat kidney labeled with Anti-CXCR7/RDC1 Polyclon...