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anti-Human PKC eta Antibodies:
anti-Mouse (Murine) PKC eta Antibodies:
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Human Polyclonal PKC eta Primary Antibody for EIA, IHC (p) - ABIN359065
Palmer, Ridden, Parker: Identification of multiple, novel, protein kinase C-related gene products. in FEBS letters 1995
Show all 2 references for ABIN359065
The association between PRKCH 1425G/A and lacunar infarction was independent of traditional stroke risk factors
Data suggest that targeted manipulation of protein kinase C (show PKC Antibodies) isoforms PKCalpha (show PKCa Antibodies), PKCbeta, and PKCeta might be beneficial in certain proteinuric kidney diseases with altered transient receptor potential cation channel subfamily C member 6 (show TRPC6 Antibodies) protein (TRPC6 (show TRPC6 Antibodies)) functions.
variant genotypes of PRKCH 1425G/A are an independent prognostic factor for ischemic stroke in the final multivariate Cox (show COX8A Antibodies) regression model
Meta-analysis indicated that the 1425G/A SNP in PRKCH may contribute to susceptibility of stroke, especially for ischemic stroke.
PKCeta promotes senescence through its ability to upregulate the expression of the cell cycle inhibitors p21Cip1 (show CDKN1A Antibodies) and p27Kip1 (show CDKN1B Antibodies) and enhance transcription and secretion of IL-6 (show IL6 Antibodies).
The 1425G/A polymorphism in PRKCH is not a significant predictor of stroke recurrence in patients with acute ischemic stroke during a 2-year follow-up period.
PKC-eta associates with NHE3 (show SLC9A3 Antibodies) and gamma tubulin (show TUBG1 Antibodies) to promote the cell polarity during migration.
the PKC family genes may play a role in the pathogenesis of MS relapse through modulating the association between 25(OH)D and relapse.
Upregulation of PKCeta contributes to breast cancer cell growth and targeting either PKCepsilon (show PRKCE Antibodies) or PDK1 (show PDK1 Antibodies) triggers PKCeta downregulation
study demonstrates that type V collagen (show COL5A1 Antibodies) induces the down-regulation of protein kinase C eta
genetic deficiency results in defective suppressive activity of T reg (show KCNH2 Antibodies) cells
data suggest that PKCeta shares some redundant roles with PKCtheta (show PRKCQ Antibodies); in T cell biology and also performs nonredundant functions that are required for T cell homeostasis and activation
Protein kinase C eta promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27Kip1 (show CDKN1B Antibodies) mRNA through suppression of JNK/c-Jun signaling under stress conditions.
these results establish a previously uncharacterized role forPKC-epsilon, PKC-eta, PKC-theta (show PRKCQ Antibodies) in T cell polarity.
ATP1A1 (show ATP1A1 Antibodies) interaction with PKCeta and occludin (show OCLN Antibodies) was involved in the integrity of the blood-labyrinth-barrier
PKC-eta/Fyn (show FYN Antibodies)-dependent pathway leading to keratinocyte growth arrest and differentiation
The expression of specific PKC isotypes was significantly changed as embryonic stem cells differentiated into cardiomyocytes.
Parvovirus infection was found to result in activation of both PDK1 (show PDPK1 Antibodies) and PKCeta, as evidenced by changes in their subcellular distribution and overall (auto)phosphorylation.
directs the induction of IRF-4 (show IRF4 Antibodies) expression downstream of BLNK (show BLNK Antibodies) in the pre-BCR (show BCR Antibodies) signaling pathway promoting kappa gene rearrangement
Translational regulation could provide an additional level for controlling the expression of PKC family members.
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.
protein kinase C, eta
, protein kinase C eta type
, protein kinase C eta type-like
, protein kinase C-eta