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Browse our Dual Specificity Phosphatase 3 Proteins (DUSP3)

Full name:
Dual Specificity Phosphatase 3 Proteins (DUSP3)
On www.antibodies-online.com are 14 Dual Specificity Phosphatase 3 (DUSP3) Proteins from 8 different suppliers available. Additionally we are shipping Dual Specificity Phosphatase 3 Antibodies (71) and Dual Specificity Phosphatase 3 Kits (2) and many more products for this protein. A total of 92 Dual Specificity Phosphatase 3 products are currently listed.
Synonyms:
2210015O03Rik, 5031436O03Rik, dusp3, RGD1560049, si:bz18k17.3, si:rp71-18k17.3, T-DSP11, VHR
list all proteins Gene Name GeneID UniProt
DUSP3 1845 P51452
Rat DUSP3 DUSP3 498003  
DUSP3 72349 Q9D7X3

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Dual Specificity Phosphatase 3 Proteins (DUSP3) by Origin

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Top referenced Dual Specificity Phosphatase 3 Proteins

  1. Human DUSP3 Protein expressed in Escherichia coli (E. coli) - ABIN667577 : Keyse: An emerging family of dual specificity MAP kinase phosphatases. in Biochimica et biophysica acta 1995 (PubMed)
    Show all 2 references for ABIN667577

  2. Human DUSP3 Protein expressed in Baculovirus infected Insect Cells - ABIN2002103 : Todd, Tanner, Denu: Extracellular regulated kinases (ERK) 1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR. A novel role in down-regulating the ERK pathway. in The Journal of biological chemistry 1999 (PubMed)
    Show all 2 references for ABIN2002103

  3. Human DUSP3 Protein expressed in Baculovirus infected Insect Cells - ABIN2002101 : Henkens, Delvenne, Arafa, Moutschen, Zeddou, Tautz, Boniver, Mustelin, Rahmouni: Cervix carcinoma is associated with an up-regulation and nuclear localization of the dual-specificity protein phosphatase VHR. in BMC cancer 2008 (PubMed)
    Show all 2 references for ABIN2002101

More Proteins for Dual Specificity Phosphatase 3 Interaction Partners

Human Dual Specificity Phosphatase 3 (DUSP3) interaction partners

  1. Data suggest levels of gene expression of both DUSP3 (dual specificity phosphatase 3) and PSME3 (proteasome activator subunit 3 (show PSME3 Proteins)) are associated with susceptibility to Staphylococcus aureus infection/sepsis in humans and in mouse disease model.

  2. Our results demonstrate that DUSP3 plays a key and nonredundant role as a regulator of innate immune responses

  3. VHR can dimerize inside cells, and that VHR catalytic activity is reduced upon dimerization.

  4. DUSP3 is a pro-angiogenic atypical dual-specificity phosphatase.

  5. DUSP3 interacting partners are nucleolar proteins involved in processes related to DNA repair and senescence.

  6. we report the first successful site-specific incorporation of sulfotyrisine into VHR through the use of expanding genetic code

  7. Proteins containing the class II motifs are efficient VHR substrates in vitro, suggesting that VHR may act on a novel class of yet unidentified Tyr (show TYR Proteins)(P) proteins in vivo.

  8. VHR expression enhances the signaling of ErbB (show EGFR Proteins) receptors and may be involved in NSCLC pathogenesis.

  9. VHR, a Vaccinia virus VH1 (show DUSP12 Proteins)-related dual-specific protein phosphatase, is phosphorylated at Y138 by ZAP-70 (show ZAP70 Proteins).

  10. VHR is required for cell-cycle progression as it modulates MAP kinase (show MAPK1 Proteins) activation in a cell-cycle phase-dependent manner.

Mouse (Murine) Dual Specificity Phosphatase 3 (DUSP3) interaction partners

  1. Data suggest levels of gene expression of both Dusp3 (dual specificity phosphatase 3) and Psme3 (proteasome activator subunit 3 (show PSME3 Proteins)) are associated with susceptibility to Staphylococcus aureus infection/sepsis in humans and in mouse disease model.

  2. Platelets from DUSP3-deficient mice displayed a selective impairment of aggregation and granule secretion.

  3. Our results demonstrate that DUSP3 plays a key and nonredundant role as a regulator of innate immune responses

  4. DUSP3 is a pro-angiogenic atypical dual-specificity phosphatase.

Dual Specificity Phosphatase 3 (DUSP3) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.

Alternative names and synonyms associated with Dual Specificity Phosphatase 3 (DUSP3)

  • dual specificity phosphatase 3 (DUSP3)
  • dual specificity phosphatase 3b (dusp3b)
  • dual specificity phosphatase 3 (Dusp3)
  • dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (Dusp3)
  • 2210015O03Rik protein
  • 5031436O03Rik protein
  • dusp3 protein
  • RGD1560049 protein
  • si:bz18k17.3 protein
  • si:rp71-18k17.3 protein
  • T-DSP11 protein
  • VHR protein

Protein level used designations for DUSP3

dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) , dual specificity phosphatase 3 , dual specificity protein phosphatase 3 , dual specificity protein phosphatase VHR , serine/threonine specific protein phosphatase , vaccinia H1-related phosphatase , vaccinia virus phosphatase VH1-related

GENE ID SPECIES
425527 Gallus gallus
468271 Pan troglodytes
568344 Danio rerio
713686 Macaca mulatta
1845 Homo sapiens
498003 Rattus norvegicus
480505 Canis lupus familiaris
615432 Bos taurus
72349 Mus musculus
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