Dual Specificity Phosphatase 3 (DUSP3) protein (Myc-DYKDDDDK Tag)
-
- Target See all Dual Specificity Phosphatase 3 (DUSP3) Proteins
- Dual Specificity Phosphatase 3 (DUSP3)
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- Myc-DYKDDDDK Tag
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human DUSP3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DUSP3 Protein
-
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-205) protein (His tag)
DUSP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-144) protein (GST tag)DUSP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (GST tag)DUSP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Dual Specificity Phosphatase 3 (DUSP3) (AA 76-185) protein (GST tag)DUSP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (Strep Tag)Crystallography grade DUSP3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (Strep Tag)Crystallography grade DUSP3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- Dual Specificity Phosphatase 3 (DUSP3)
- Alternative Name
- Dusp3 (DUSP3 Products)
- Synonyms
- dusp3 Protein, si:bz18k17.3 Protein, si:rp71-18k17.3 Protein, VHR Protein, RGD1560049 Protein, 2210015O03Rik Protein, 5031436O03Rik Protein, T-DSP11 Protein, dual specificity phosphatase 3 Protein, dual specificity phosphatase 3b Protein, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) Protein, DUSP3 Protein, dusp3b Protein, Dusp3 Protein
- Target Type
- Viral Protein
- Background
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.
- Molecular Weight
- 20.3 kDa
- NCBI Accession
- NP_004081
- Pathways
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
-
