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Browse our anti-ITSN1 (ITSN1) Antibodies

Full name:
anti-Intersectin 1 Antibodies (ITSN1)
On www.antibodies-online.com are 12 Intersectin 1 (ITSN1) Antibodies from 7 different suppliers available. Additionally we are shipping ITSN1 Kits (3) and and many more products for this protein. A total of 17 ITSN1 products are currently listed.
Synonyms:
AA517634, AA545208, AI316805, AI839402, AI848451, Ehsh1, Ese1, ITSN, itsn-A, ITSN1, SH3, SH3D1A, SH3P17, si:dz173a8.1
list all antibodies Gene Name GeneID UniProt
ITSN1 16443 Q9Z0R4
ITSN1 6453 Q15811
ITSN1 29491 Q9WVE9

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Most Popular Reactivities for anti-ITSN1 (ITSN1) Antibodies

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anti-Mouse (Murine) ITSN1 Antibodies:

anti-Human ITSN1 Antibodies:

anti-Rat (Rattus) ITSN1 Antibodies:

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More Antibodies against ITSN1 Interaction Partners

Mouse (Murine) Intersectin 1 (ITSN1) interaction partners

  1. PRRT2 (show PRRT2 Antibodies) interacts with the Src (show SRC Antibodies) homology 3 domain-bearing protein Intersectin 1, an intracellular protein (show CKAP2 Antibodies) involved in synaptic vesicle cycling.

  2. Endocytic deficiency caused by ITSN knock-down modified Alk5 (show TGFBR1 Antibodies) endocytic trafficking and enhances its degradation

  3. It was concluded that miR (show MLXIP Antibodies)-194 regulates ROMK (show KCNJ1 Antibodies) channel activity by modulating ITSN1 expression thereby enhancing ITSN1/WNK-dependent endocytosis.

  4. ITSN1 enhances Cbl (show CBL Antibodies) activity, in part, by modulating the interaction of Cbl (show CBL Antibodies) with Spry2 (show SPRY2 Antibodies) through recruitment of Shp2 (show PTPN11 Antibodies) phosphatase to the Cbl (show CBL Antibodies)-Spry2 (show SPRY2 Antibodies) complex.

  5. This study demonistrated that Itsn1 mutant mice showed severe deficits in Morris water maze and contextual fear memory tasks.

  6. ITSN1 binds Pro-rich regions in both Cbl (show CBL Antibodies) and Spry2 (show SPRY2 Antibodies), and interaction of ITSN1 with Spry2 (show SPRY2 Antibodies) disrupts Spry2 (show SPRY2 Antibodies)-Cbl (show CBL Antibodies) interaction, resulting in enhanced ubiquitylation of the EGFR (show EGFR Antibodies).

  7. Data show that intersectin-SH3D interacts directly with a small region of CdGAP (show ARHGAP31 Antibodies) highly enriched in basic residues and comprising a novel conserved xKx(K/R)K motif.

  8. Swapping of SH3 domain binding partners might act as a switch controlling the actin nucleation activity of intersectin 1L.

  9. Cdc42 (show CDC42 Antibodies) and Ras cooperate to mediate cellular transformation by intersectin-L

  10. Data suggest that PI3K-C2beta (show PIK3C2B Antibodies) and AKT (show AKT1 Antibodies) are epistatic to intersectin, and show that ITSN, independent of its role in endocytosis, regulates a critical cellular signaling pathway necessary for cell survival.

Human Intersectin 1 (ITSN1) interaction partners

  1. Study suggests critical roles of ITSN1-S in malignant glioma proliferation, indicating a potential usage of ITSN1-S in the therapeutic intervention as a novel molecular target

  2. Our observations suggest that ITSN1 is an important general regulator of Cdc42-, Nck- and N-WASP-dependent actin polymerisation

  3. ITSN1 and ITSN2 bind similar proline-rich ligands but are differentially recognized by SH2 domain-containing proteins.

  4. Silencing ITSN1 significantly inhibits the anchorage independent growth of tumor cells in vitro.

  5. the neuron-specific isoform of the stable tubule-only polypeptide (show MAP6 Antibodies) (STOP) interacts with SH3A domain of ITSN1.

  6. ITSN-1s, via its SH3A domain has the unique ability to regulate dyn2 (show DNM2 Antibodies) assembly-disassembly and function during endocytosis

  7. ITSN1 has two isoforms: ITSN1-long and ITSN1-short. siRNA-mediated down regulation of ITSN1-short inhibits migration and invasion of glioma cells.

  8. study reveals a link between overexpression of specific ITSN1 isoforms and behavioral phenotypes

  9. This novel mammalian ITSN1 isoform possesses a significantly altered domain structure and performs specific protein-protein interactions.

  10. Studied the inhibitory mechanism of ITSN1L, & id'd a novel short amino acid motif which mediates autoinhibition. Found this motif is located in the SH3 DH linker region, and show that W1221 acts as key residue in establishing inhibitory interaction.

ITSN1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far.

Alternative names and synonyms associated with ITSN1

  • intersectin 1 (SH3 domain protein) (itsn1) antibody
  • intersectin 1 (ITSN1) antibody
  • intersectin 1 (LOC100358300) antibody
  • intersectin 1 (SH3 domain protein 1A) (Itsn1) antibody
  • intersectin 1 (SH3 domain protein) (ITSN1) antibody
  • intersectin 1 (SH3 domain protein) (Itsn1) antibody
  • AA517634 antibody
  • AA545208 antibody
  • AI316805 antibody
  • AI839402 antibody
  • AI848451 antibody
  • Ehsh1 antibody
  • Ese1 antibody
  • ITSN antibody
  • itsn-A antibody
  • ITSN1 antibody
  • SH3 antibody
  • SH3D1A antibody
  • SH3P17 antibody
  • si:dz173a8.1 antibody

Protein level used designations for anti-Intersectin 1 (ITSN1) Antibodies

SH3 domain , intersectin-1 , intersectin 1 , intersectin 1, isoform 1 , EH and SH3 domains protein 1 , Eh domain, SH3 domain regulator of endocytosis 1 , intersectin (SH3 domain protein 1A) , intersectin short form 2 variant 2 , intersectin-L , SH3 domain-containing protein 1A , Src homology 3 domain-containing protein , human intersectin-SH3 domain-containing protein SH3P17 , intersectin 1 short form variant 3 , intersectin 1 short form variant, 11 , intersectin short variant 12 , EH domain and SH3 domain regulator of endocytosis 1 , intersectin 1 (SH3 domain protein 1A)

GENE ID SPECIES
368504 Danio rerio
698606 Macaca mulatta
100137549 Papio anubis
100358300 Oryctolagus cuniculus
16443 Mus musculus
6453 Homo sapiens
29491 Rattus norvegicus
394300 Xenopus laevis
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