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Browse our Neuronal Guanine Nucleotide Exchange Factor Proteins (NGEF)

Full name:
Neuronal Guanine Nucleotide Exchange Factor Proteins (NGEF)
On www.antibodies-online.com are 5 Neuronal Guanine Nucleotide Exchange Factor (NGEF) Proteins from 4 different suppliers available. Additionally we are shipping Neuronal Guanine Nucleotide Exchange Factor Antibodies (34) and Neuronal Guanine Nucleotide Exchange Factor Kits (3) and many more products for this protein. A total of 42 Neuronal Guanine Nucleotide Exchange Factor products are currently listed.
Synonyms:
ARHGEF27, Besh3, ephexin, ephexin-1, Tims2
list all proteins Gene Name GeneID UniProt
NGEF 25791 Q8N5V2
NGEF 53972 Q8CHT1
NGEF 246217  

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Neuronal Guanine Nucleotide Exchange Factor Proteins (NGEF) by Origin

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More Proteins for Neuronal Guanine Nucleotide Exchange Factor Interaction Partners

Human Neuronal Guanine Nucleotide Exchange Factor (NGEF) interaction partners

  1. A visceral-fat-associated SNP, rs11678490 of NGEF, was found in Korean men.

  2. FGFR (show FGFR2 Proteins)-mediated phosphorylation of ephexin1 enhances the guanine nucleotide exchange activity toward RhoA (show RHOA Proteins) without affecting the activity to Rac1 or Cdc42 (show CDC42 Proteins).

Mouse (Murine) Neuronal Guanine Nucleotide Exchange Factor (NGEF) interaction partners

  1. An essential role is identified for rho guanine nucleotide exchange factor (RhoGEF) ephexin1 in the maturation of acetylcholine receptor clusters.

  2. FGFR (show FGFR2 Proteins)-mediated phosphorylation of ephexin1 enhances the guanine nucleotide exchange activity toward RhoA (show RHOA Proteins) without affecting the activity to Rac1 or Cdc42 (show CDC42 Proteins).

Neuronal Guanine Nucleotide Exchange Factor (NGEF) Protein Profile

Protein Summary

Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).

Alternative names and synonyms associated with Neuronal Guanine Nucleotide Exchange Factor (NGEF)

  • neuronal guanine nucleotide exchange factor (NGEF)
  • neuronal guanine nucleotide exchange factor (LOC100227330)
  • neuronal guanine nucleotide exchange factor (Ngef)
  • ARHGEF27 protein
  • Besh3 protein
  • ephexin protein
  • ephexin-1 protein
  • Tims2 protein

Protein level used designations for NGEF

neuronal guanine nucleotide exchange factor , ephexin-1 , eph-interacting exchange protein , ephexin-1-like , transforming immortalised mammary epithelial sequence 2 , brain-enriched SH3-domain protein Besh3 , ephexin1 , guanine nucleotide exchange factor

GENE ID SPECIES
460020 Pan troglodytes
486165 Canis lupus familiaris
540756 Bos taurus
100057337 Equus caballus
100171841 Pongo abelii
100227330 Taeniopygia guttata
100403559 Callithrix jacchus
100546967 Meleagris gallopavo
100618016 Monodelphis domestica
25791 Homo sapiens
53972 Mus musculus
246217 Rattus norvegicus
424744 Gallus gallus
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