anti-Ferret Insulin antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Insulin Antibody (supplied by: Log in to see )

Antigen
Insulin (INS) Antibodies
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • insulin-like
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • Ins2
  • LOC100060077
Reactivity
Ferret, Human, Pig (Porcine), Rat (Rattus)
933
394
284
271
262
121
49
6
6
5
5
5
4
2
2
1
1
1
1
1
1
1
Host
Guinea Pig
822
176
54
16
2
1
Clonality
Polyclonal
Conjugate
This Insulin antibody is un-conjugated
55
42
41
27
26
26
21
21
18
17
17
17
17
17
17
16
16
12
11
10
9
9
9
5
5
5
5
5
5
2
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
615
361
243
222
204
200
157
137
70
66
38
29
14
11
9
9
8
7
5
4
3
3
2
2
2
1
1
1
Supplier
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Catalog No. ABIN113470
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN113504 EIA IHC (fro) IHC (p) Rabbit Log in to see Polyclonal 1

Top referenced anti-Insulin antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-Insulin Antibodies

Application / Reactivity Human Pig (Porcine) Rat (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 5 Antibodies 5 Antibodies 1 Antibodies
Cytometry by Time of Flight (CyTOF) 14 Antibodies 12 Antibodies 4 Antibodies
Western Blotting (WB) 188 Antibodies 107 Antibodies 51 Antibodies
Radioimmunoassay (RIA) 32 Antibodies 13 Antibodies 4 Antibodies
Protein Assay (PrA) 6 Antibodies 2 Antibodies
Neutralization (Neut) 2 Antibodies 2 Antibodies
Immunoradiometric Assay (IRMA) 1 Antibodies
Immunoprecipitation (IP) 65 Antibodies 54 Antibodies

General

Antigen Insulin (INS) Antibodies
Reactivity Ferret, Human, Pig (Porcine), Rat (Rattus)
(933), (394), (284), (271), (262), (121), (49), (6), (6), (5), (5), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Guinea Pig
(822), (176), (54), (16), (2), (1)
Clonality
Polyclonal
Conjugate This Insulin antibody is un-conjugated
(55), (42), (41), (27), (26), (26), (21), (21), (18), (17), (17), (17), (17), (17), (17), (16), (16), (12), (11), (10), (9), (9), (9), (5), (5), (5), (5), (5), (5), (2), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(615), (361), (243), (222), (204), (200), (157), (137), (70), (66), (38), (29), (14), (11), (9), (9), (8), (7), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling ProductDetails: References for anti-Insulin antibody (ABIN113470) Images
Specificity The antibody recognizes Insulin produced by the B-cells of the pancreatic islets and by Insulin-producing islet cell tumors. No cross-reactions with polypeptide hormones unrelated to Insulin.
Cross-Reactivity (Details) Species reactivity (tested):Human, Pig, Rat and Ferret.
Purification Serum
Immunogen Porcine Insulin (Novo)

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling ProductDetails: References for anti-Insulin antibody (ABIN113470) Images back to top
Antigen
Alternative Name Insulin (INS Antibody Abstract)
Background Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
Gene ID 3630
NCBI Accession NP_000198
UniProt P01308
Research Area Neurology, Diabetes, Hormones
Pathways NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling ProductDetails: References for anti-Insulin antibody (ABIN113470) Images back to top
Application Notes Immunofluorescence: 1/400-1/800 using FITC with overnight incubation at 2-8 °C. Immunohistochemistry on Frozen and Paraffin Sections. Recommended Positive Control: Formalin-fixed paraffin sections of pig pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details ProductDetails: References for anti-Insulin antibody (ABIN113470) Images back to top
Format Liquid
Reconstitution Dissolve the antiserum in 50-100 μL distilled water, and dilute further in 0.1M PBS with 1 % BSA and 0.09 % Sodium Azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

ProductDetails: References for anti-Insulin antibody (ABIN113470)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Background publications

Luts, Sundler: "Peptide-containing nerve fibers in the respiratory tract of the ferret." in: Cell and tissue research, Vol. 258, Issue 2, pp. 259-67, 1990

Ahrén, Böttcher, Ekman, Sundler: "Cysteamine and the endocrine pancreas: immunocytochemical, immunochemical, and functional aspects." in: Cell and tissue research, Vol. 256, Issue 1, pp. 159-66, 1989