anti-Human Insulin antibody for Functional Studies

Recommended Insulin Antibody (supplied by: Log in to see )

Antigen
Insulin (INS) Antibodies
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • insulin-like
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • Ins2
  • LOC100060077
Reactivity
Cow (Bovine), Human, Pig (Porcine)
941
398
284
272
263
121
49
6
6
5
5
5
4
3
2
1
1
1
1
1
1
1
Host
Mouse
829
179
55
16
3
1
Clonality
Monoclonal
Conjugate
This Insulin antibody is un-conjugated
55
42
41
27
26
26
21
21
18
17
17
17
17
17
17
16
16
12
11
10
9
9
9
5
5
5
5
5
5
2
1
Application
Enzyme Immunoassay (EIA), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA)
617
373
244
228
207
204
161
138
69
66
37
28
14
11
9
8
8
7
5
4
3
3
2
2
2
1
1
1
Supplier
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Catalog No. ABIN111965
$ 253.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN125983 EIA Func IHC (fro) IHC (p) RIA Mouse IgG1 Log in to see IN-05 1
1 ABIN94408 Func ICC IHC (p) RIA ELISA Mouse IgG1 Log in to see IN-05 1
1 ABIN206973 BR ELISA Func ICC IHC (p) Neut RIA Mouse IgG1 Log in to see IN-05
1 ABIN206900 BR ELISA Func ICC IHC (p) Neut RIA Mouse IgG1 Log in to see IN-05
1 ABIN3200648 ELISA Func ICC IHC (p) RIA Mouse IgG1 Log in to see IN-05
1 ABIN3200649 ELISA Func ICC IHC (p) RIA Mouse IgG1 Log in to see IN-05
1 ABIN3200650 ELISA Func ICC IHC (p) RIA Mouse IgG1 Log in to see IN-05
1 ABIN2749217 Func ICC IHC (p) RIA ELISA Mouse IgG1 Log in to see IN-05

Top referenced anti-Insulin antibody for Functional Studies

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Application / Reactivity Pig (Porcine)
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Cytometry by Time of Flight (CyTOF) 12 Antibodies
Dot Blot (DB) 3 Antibodies
ELISA 206 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 15 Antibodies
Flow Cytometry (FACS) 137 Antibodies
Functional Studies (Func) 9 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 90 Antibodies
Immunodiffusion (ID) 1 Antibodies
Immunoelectron Microscopy (IEM) 1 Antibodies
Immunofluorescence (IF) 109 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 88 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies

General

Antigen Insulin (INS) Antibodies
Reactivity Cow (Bovine), Human, Pig (Porcine)
(941), (398), (284), (272), (263), (121), (49), (6), (6), (5), (5), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(829), (179), (55), (16), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Insulin antibody is un-conjugated
(55), (42), (41), (27), (26), (26), (21), (21), (18), (17), (17), (17), (17), (17), (17), (16), (16), (12), (11), (10), (9), (9), (9), (5), (5), (5), (5), (5), (5), (2), (1)
Application Enzyme Immunoassay (EIA), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA)
(617), (373), (244), (228), (207), (204), (161), (138), (69), (66), (37), (28), (14), (11), (9), (8), (8), (7), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling ProductDetails: References for anti-Insulin antibody (ABIN111965) Images
Specificity The antibody reacts with insulin, one of the major regulatory endocrine hormones of intermediate metabolism, normally secreted by the beta cells (a type of islet cells) of the pancreas, it is also present in tumors of B cell origin such as insulinoma. The antibody IN-05 blocks binding of Insulin to the receptor.
Purification Affinity Chromatography on Protein A.
Immunogen Porcine Insulin
Clone IN-05
Isotype IgG1

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling ProductDetails: References for anti-Insulin antibody (ABIN111965) Images back to top
Antigen
Alternative Name Insulin (INS Antibody Abstract)
Background Insulin and glucagon are pancreatic endocrine hormones secreted by islet cells within the pancreas. The stimulus for insulin secretion is a HIGH blood glucose. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population.Synonyms: INS
Gene ID 3630
NCBI Accession NP_000198
UniProt P01308
Research Area Neurology, Diabetes, Hormones
Pathways NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling ProductDetails: References for anti-Insulin antibody (ABIN111965) Images back to top
Application Notes Immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections. Immunocytochemistry. ELISA. RIA. Functional Applications (The antibody blocks binding of insulin to the receptor).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details ProductDetails: References for anti-Insulin antibody (ABIN111965) Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.3 with 15 mM Sodium Azide as presrevative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

ProductDetails: References for anti-Insulin antibody (ABIN111965)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Background publications

Horejsí, Hilgert, Kristofová, Satayalai: "Murine hybridoma monoclonal antibodies against insulin: cross-reactivity with insulins of three species and blocking of insulin binding to its receptor." in: Immunology letters, Vol. 8, Issue 5, pp. 279-83, 1985