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anti-Mouse (Murine) IRAK4 antibody for Enzyme Immunoassay

Recommended IRAK4 Antibody (supplied by: Log in to see )

Antigen
Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Antibodies
  • 8430405M07Rik
  • 9330209D03Rik
  • IPD1
  • ipd1
  • irak-4
  • IRAK-4
  • irak4
  • IRAK4
  • ny-ran-64
  • NY-REN-64
  • ny-ren-64
  • ren64
  • REN64
  • zgc:55553
Epitope
N-Term
48
45
16
15
14
13
13
6
5
5
4
4
3
3
3
3
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
181
47
19
7
2
2
2
1
1
1
1
1
Host
Goat
138
30
24
Clonality
Polyclonal
Conjugate
This IRAK4 antibody is un-conjugated
9
8
7
6
5
5
4
3
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
146
86
27
22
22
11
10
6
6
6
4
3
2
2
1
1
Supplier
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Catalog No. ABIN782953
$ 203.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008854307 ABIN374511 EIA WB Goat N-Term Log in to see Polyclonal 1
0.0008854307 ABIN615818 EIA IHC (p) WB Goat N-Term Log in to see Polyclonal
0.0008854307 ABIN1107881 EIA IHC (p) WB Mouse IgG1 Log in to see 2H9

Top referenced anti-IRAK4 antibody for Enzyme Immunoassay

Similar anti-IRAK4 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 18 Antibodies 80 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies 7 Antibodies
Flow Cytometry (FACS) 4 Antibodies 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 22 Antibodies
Immunohistochemistry (IHC) 9 Antibodies 21 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 35 Antibodies
ELISA (Capture) 1 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 11 Antibodies
Immunofluorescence (IF) 10 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 2 Antibodies

General

Antigen Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Antibodies
Epitope N-Term
(48), (45), (16), (15), (14), (13), (13), (6), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(181), (47), (19), (7), (2), (2), (2), (1), (1), (1), (1), (1)
Host Goat
(138), (30), (24)
Clonality
Polyclonal
Conjugate This IRAK4 antibody is un-conjugated
(9), (8), (7), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(146), (86), (27), (22), (22), (11), (10), (6), (6), (6), (4), (3), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-IRAK4 Antibody

Target Details IRAK4 Application Details Handling References for anti-IRAK4 Antibody (ABIN782953) Images
Sequence NKPITPSTYV RC
Specificity This antibody recognizes IRAK4 at N-term.
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Purification Affinity Chromatography
Immunogen Peptide with sequence from the N Terminus of the protein sequence according to NP_057207.2, NP_001107654.1. Genename: IRAK4

Target Details IRAK4

Product Details anti-IRAK4 Antibody Application Details Handling References for anti-IRAK4 Antibody (ABIN782953) Images back to top
Antigen
Alternative Name IRAK4 (IRAK4 Antibody Abstract)
Background Interleukin 1 (IL1) and lipopolysaccharide (LPS) induces cellular responses through IL1 receptor (IL1R) and Toll like receptors (TLR). IL1R associated kinases (IRAK, IRAK2, and IRAKM) regulate the activation of NF-kB and MAP kinase (MAPK) by IL1R/TLR. A novel member in the IRAK/Pelle family was recently identified and designated IRAK4. Overexpression of IRAK4 activates NF-kB and MAPK pathways. IRAK4 interacts with and phosphorylates IRAK1. IRAK4 deficient animals are completely resistant to the challenge with LPS. Animals and humans lacking IRAK4 are impaired in their responses to viral and bacterial challenges. Members in IRAK/Pelle family play a central role in IL1R/TLR mediated inflammatory responses and in innate immunity.Synonyms: IRAK-4, Interleukin-1 receptor-associated kinase-like, NY-REN-64
Gene ID 51135
NCBI Accession NP_001107654
UniProt Q9NWZ3
Research Area Immunology, Innate Immunity, Atherosclerosis, Cytokines, Receptors, Inflammation
Pathways NF-kappaB Signaling, TLR Signaling

Application Details

Product Details anti-IRAK4 Antibody Target Details IRAK4 Handling References for anti-IRAK4 Antibody (ABIN782953) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IRAK4 Antibody Target Details IRAK4 Application Details References for anti-IRAK4 Antibody (ABIN782953) Images back to top
Concentration 0.5 mg/mL
Buffer Tris saline containing 0.02 % Sodium Azide, pH 7.3 with 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-IRAK4 Antibody (ABIN782953)

Product Details anti-IRAK4 Antibody Target Details IRAK4 Application Details Handling Images back to top
Background publications

Lye, Mirtsos, Suzuki, Suzuki, Yeh: "The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling." in: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40653-8, 2004

Images

Product Details anti-IRAK4 Antibody Target Details IRAK4 Application Details Handling References for anti-IRAK4 Antibody (ABIN782953) back to top
Supplier Images
 image for anti-IRAK4 antibody (Interleukin-1 Receptor-Associated Kinase 4) (N-Term) (ABIN782953) anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (N-Term) antibody