anti-Mouse (Murine) IRAK4 antibody for Enzyme Immunoassay

Recommended IRAK4 Antibody (supplied by: Log in to see )

Antigen
Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Antibodies
  • zgc:55553
  • IRAK4
  • ipd1
  • irak-4
  • ny-ran-64
  • ny-ren-64
  • ren64
  • irak4
  • IPD1
  • IRAK-4
  • NY-REN-64
  • REN64
  • 8430405M07Rik
  • 9330209D03Rik
  • interleukin-1 receptor-associated kinase 4
  • Interleukin-1 receptor-associated kinase 4
  • IRAK4
  • irak4
  • LOC100227974
  • Irak4
Epitope
N-Term
39
31
16
15
15
15
14
6
6
6
5
5
5
5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
193
54
27
13
5
4
4
4
2
2
2
2
1
Host
Goat
145
33
23
Clonality
Polyclonal
Conjugate
This IRAK4 antibody is un-conjugated
9
8
7
6
5
5
4
3
2
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
152
90
27
26
26
11
11
9
7
4
3
2
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Catalog No. ABIN5553039
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN615818 EIA IHC (p) WB Goat N-Term Log in to see Polyclonal
1 ABIN1107881 EIA IHC (p) WB Mouse IgG1 Log in to see 2H9

General

Antigen Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Antibodies
Epitope N-Term
(39), (31), (16), (15), (15), (15), (14), (6), (6), (6), (5), (5), (5), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(193), (54), (27), (13), (5), (4), (4), (4), (2), (2), (2), (2), (1)
Host Goat
(145), (33), (23)
Clonality
Polyclonal
Conjugate This IRAK4 antibody is un-conjugated
(9), (8), (7), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(152), (90), (27), (26), (26), (11), (11), (9), (7), (4), (3), (2), (2), (1), (1), (1)
Supplier Log in to see

Product Details anti-IRAK4 Antibody

Target Details IRAK4 Application Details Handling Images
Sequence NKPITPSTYV RC
Specificity This antibody recognizes IRAK4 at N-term.
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Purification Affinity Chromatography
Immunogen Peptide with sequence from the N Terminus of the protein sequence according to NP_057207.2, NP_001107654.1. Genename: IRAK4

Target Details IRAK4

Product Details anti-IRAK4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name IRAK4 (IRAK4 Antibody Abstract)
Background Interleukin 1 (IL1) and lipopolysaccharide (LPS) induces cellular responses through IL1 receptor (IL1R) and Toll like receptors (TLR). IL1R associated kinases (IRAK, IRAK2, and IRAKM) regulate the activation of NF-kB and MAP kinase (MAPK) by IL1R/TLR. A novel member in the IRAK/Pelle family was recently identified and designated IRAK4. Overexpression of IRAK4 activates NF-kB and MAPK pathways. IRAK4 interacts with and phosphorylates IRAK1. IRAK4 deficient animals are completely resistant to the challenge with LPS. Animals and humans lacking IRAK4 are impaired in their responses to viral and bacterial challenges. Members in IRAK/Pelle family play a central role in IL1R/TLR mediated inflammatory responses and in innate immunity.Synonyms: IRAK-4, Interleukin-1 receptor-associated kinase-like, NY-REN-64
Gene ID 51135
NCBI Accession NP_001107654
UniProt Q9NWZ3
Research Area Atherosclerosis, Cytokines, Immunology, Inflammation, Innate Immunity, Receptors
Pathways NF-kappaB Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades

Application Details

Product Details anti-IRAK4 Antibody Target Details IRAK4 Handling Images back to top
Application Notes Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IRAK4 Antibody Target Details IRAK4 Application Details Images back to top
Concentration 0.5 mg/mL
Buffer Tris saline containing 0.02 % Sodium Azide, pH 7.3 with 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.