anti-Dog (Canine) NFKBIB antibody for Western Blotting

Recommended NFKBIB Antibody (supplied by: Log in to see )

Antigen
Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta (NFKBIB) Antibodies
  • NFKBIB
  • IKB-beta
  • IKappaBbeta
  • IkB
  • IkBb
  • IKBB
  • TRIP9
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
  • NFKBIB
  • LOC100359283
  • Nfkbib
Epitope
N-Term
48
20
18
14
12
10
6
4
4
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
198
99
82
9
7
7
6
4
4
1
1
1
Host
Rabbit
165
37
Clonality
Polyclonal
Conjugate
This NFKBIB antibody is un-conjugated
6
6
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
139
78
76
36
28
24
14
8
4
3
1
1
Options
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Catalog No. ABIN2775762
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.146931 ABIN2775761 WB Rabbit Middle Region Log in to see Polyclonal
3.146931 ABIN2775838 WB Rabbit N-Term Log in to see Polyclonal 1
3.146931 ABIN2775837 IHC WB Rabbit C-Term Log in to see Polyclonal 1
1 ABIN203071 IHC (p) WB Rabbit IgG AA 282-331 Log in to see Polyclonal
1 ABIN467988 WB Rabbit AA 287-336 Log in to see Polyclonal
1 ABIN601595 IHC WB Rabbit IgG Log in to see Polyclonal

General

Antigen Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta (NFKBIB) Antibodies
Epitope N-Term
(48), (20), (18), (14), (12), (10), (6), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
(198), (99), (82), (9), (7), (7), (6), (4), (4), (1), (1), (1)
Host Rabbit
(165), (37)
Clonality
Polyclonal
Conjugate This NFKBIB antibody is un-conjugated
(6), (6), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Western Blotting (WB)
(139), (78), (76), (36), (28), (24), (14), (8), (4), (3), (1), (1)
Pubmed 1 reference available
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Product Details anti-NFKBIB Antibody

Target Details NFKBIB Application Details Handling References for anti-NFKBIB antibody (ABIN2775762) Images
Blocking Peptide Blocking peptide for this product available: ABIN980675
Sequence LVFGYVTEDG DTALHLAVIH QHEPFLDFLL GFSAGTEYMD LQNDLGQTAL
Predicted Reactivity Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against NFKBIB. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human NFKBIB

Target Details NFKBIB

Product Details anti-NFKBIB Antibody Application Details Handling References for anti-NFKBIB antibody (ABIN2775762) Images back to top
Antigen
Alternative Name NFKBIB (NFKBIB Antibody Abstract)
Background NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).[supplied by OMIM].
Alias Symbols: IKBB, TRIP9
Protein Interaction Partner: VPS52, UBC, BAG3, TSPAN1, GIT2, RELA, REL, CSNK2A1, CDC25A, BAK1, APP, ZBTB7A, DNAJA3, IKBKB, CHUK, BRAP, IKBKG, TRE17, NFKBIA, NCOR2, PPARG, ESR2, POLR1D, POLR1E, POLR1A, POLR1C, POLR2H, NKIRAS2, POLR1B, NKIRAS1, LRPPRC, RASAL2, MTIF2, BTRC, CUL1, SKP1,
Protein Size: 356
Molecular Weight 38 kDa
Gene ID 4793
NCBI Accession NM_002503, NP_002494
UniProt Q15653
Pathways NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades

Application Details

Product Details anti-NFKBIB Antibody Target Details NFKBIB Handling References for anti-NFKBIB antibody (ABIN2775762) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 356 AA

Restrictions For Research Use only

Handling

Product Details anti-NFKBIB Antibody Target Details NFKBIB Application Details References for anti-NFKBIB antibody (ABIN2775762) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NFKBIB antibody (ABIN2775762)

Product Details anti-NFKBIB Antibody Target Details NFKBIB Application Details Handling Images back to top
Background publications

Joo, Hahn, Kwon, Sadikot, Blackwell, Christman: "Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta." in: Journal of virology, Vol. 79, Issue 12, pp. 7648-57, 2005

Images

Product Details anti-NFKBIB Antibody Target Details NFKBIB Application Details Handling References for anti-NFKBIB antibody (ABIN2775762) back to top
Supplier Images
Western Blotting (WB) image for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta (NFKBIB) (N-Term) antibody (ABIN2775762) WB Suggested Anti-NFKBIB Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta (NFKBIB) (N-Term) antibody (ABIN2775762) WB Suggested Anti-NFKBIB
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.500 <...