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anti-Human NFKBIB antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended NFKBIB Antibody (supplied by: Log in to see )

Antigen
Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta (NFKBIB) Antibodies
  • IKappaBbeta
  • IkB
  • IKB-beta
  • IKBB
  • IkBb
  • NFKBIB
  • TRIP9
Epitope
AA 56-145
33
28
16
15
12
6
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
156
64
54
4
4
Host
Mouse
130
30
Clonality
Monoclonal
Conjugate
This NFKBIB antibody is un-conjugated
6
6
5
3
3
3
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
106
62
62
26
24
17
12
6
3
3
1
1
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Catalog No. ABIN393462
$ 450.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.33769524 ABIN218517 IF IHC (p) IP ELISA WB Rabbit C-Term Log in to see Polyclonal
0.0009015372 ABIN197074 IHC (p) Rabbit pSer23 Log in to see Polyclonal 2
0.0009015372 ABIN657702 IHC (p) WB Rabbit Ig AA 326-355, C-Term Log in to see Polyclonal
0.0009015372 ABIN3043567 IHC (p) WB Rabbit IgG AA 56-237 Log in to see Polyclonal
0.0009015372 ABIN303120 EIA IF IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal
0.0009015372 ABIN257353 IHC (p) IHC WB Rabbit IgG Ser23 Log in to see Polyclonal
0.0009015372 ABIN598839 IHC (p) ELISA Mouse IgG2a, kappa Log in to see 1B5
0.0009015372 ABIN2743233 IHC (p) WB Rabbit IgG AA 56-237 Log in to see Polyclonal
0.0009015372 ABIN518334 IF IHC (p) WB Mouse AA 1-356, full length Log in to see Polyclonal
0.0009015372 ABIN742630 IHC (p) WB Biotin Rabbit IgG pSer23 Log in to see Polyclonal
0.0009015372 ABIN742637 IHC (p) WB HRP Rabbit IgG pSer23 Log in to see Polyclonal
0.0009015372 ABIN742628 IF (p) IHC (p) WB Rabbit IgG pSer23 Log in to see Polyclonal
0.0009015372 ABIN561984 IHC (p) ELISA Mouse IgG2a kappa AA 56-145, partial Log in to see 1B5
0.0009015372 ABIN1811861 IHC (p) WB Rabbit AA 325-355 Log in to see Polyclonal
0.0009015372 ABIN1838548 IHC (p) Rabbit pSer23 Log in to see Polyclonal
0.0009015372 ABIN2475866 IHC (p) Mouse IgG2a AA 56-145 Log in to see 1B5
0.0009015372 ABIN738486 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0009015372 ABIN1712429 IHC (p) WB HRP Rabbit IgG pSer19 Log in to see Polyclonal
0.0009015372 ABIN1701412 IHC (p) WB Biotin Rabbit IgG pSer19 Log in to see Polyclonal
0.0009015372 ABIN408419 IHC (p) IHC WB Rabbit IgG Ser23 Log in to see Polyclonal

Similar anti-NFKBIB Antibodies

Application / Reactivity Human
ELISA 60 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunofluorescence (IF) 17 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 24 Antibodies
Immunohistochemistry (IHC) 64 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 28 Antibodies
Immunoprecipitation (IP) 12 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 105 Antibodies

General

Antigen Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta (NFKBIB) Antibodies
Epitope AA 56-145
(33), (28), (16), (15), (12), (6), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(156), (64), (54), (4), (4)
Host Mouse
(130), (30)
Clonality (Clone)
Monoclonal   ( )
Conjugate This NFKBIB antibody is un-conjugated
(6), (6), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
(106), (62), (62), (26), (24), (17), (12), (6), (3), (3), (1), (1)
Pubmed 5 references available
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Product Details anti-NFKBIB Antibody

Target Details NFKBIB Application Details Handling References for anti-NFKBIB Antibody (ABIN393462) Images
Specificity NFKBIB (AAH15528, 56 a.a. ~ 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen NFKBIB (AAH15528, 56 a.a. ~ 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1B5
Isotype IgG2a kappa

Target Details NFKBIB

Product Details anti-NFKBIB Antibody Application Details Handling References for anti-NFKBIB Antibody (ABIN393462) Images back to top
Antigen
Alternative Name NFKBIB (NFKBIB Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 37771 DA
Gene ID 12406
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Protein Modifications, Cell Structure
Pathways NF-kappaB Signaling

Application Details

Product Details anti-NFKBIB Antibody Target Details NFKBIB Handling References for anti-NFKBIB Antibody (ABIN393462) Images back to top
Application Notes ELISA ~~ 1ug/ml~3ng/ml Immunohistochemistry ~~ 1.5ug/ml
Comment

Background: NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).

Restrictions For Research Use only

Handling

Product Details anti-NFKBIB Antibody Target Details NFKBIB Application Details References for anti-NFKBIB Antibody (ABIN393462) Images back to top
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months

References for anti-NFKBIB Antibody (ABIN393462)

Product Details anti-NFKBIB Antibody Target Details NFKBIB Application Details Handling Images back to top
Background publications

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Potter, Cordell, Barton, Daly, Hyrich, Mann, Morgan, Wilson, Isaacs: "Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways." in: Annals of the rheumatic diseases, Vol. 69, Issue 7, pp. 1315-20, 2010

Segat, Brandão, Guimarães, Pontillo, Athanasakis, de Oliveira, Arraes, de Lima Filho, Crovella: "Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment." in: Vaccine, Vol. 28, Issue 10, pp. 2201-6, 2010

McGeachie, Ramoni, Mychaleckyj, Furie, Dreyfuss, Liu, Herrington, Guo, Lima, Post, Rotter, Rich, Sale, Ramoni: "Integrative predictive model of coronary artery calcification in atherosclerosis." in: Circulation, Vol. 120, Issue 24, pp. 2448-54, 2009

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009

Images

Product Details anti-NFKBIB Antibody Target Details NFKBIB Application Details Handling References for anti-NFKBIB Antibody (ABIN393462) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-NFKBIB antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta) (AA 56-145) (ABIN393462) Immunoperoxidase of monoclonal antibody to NFKBIB on formalin-fixed paraffin-embedded...
Immunohistochemistry (IHC) image for anti-NFKBIB antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta) (AA 56-145) (ABIN393462) anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta (NFKBIB) (AA 56-145) antibody (Image 2)