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|Antigen||Nerve Growth Factor beta (NGFB) Antibodies|
|Epitope||AA 162-173, N-Term Alternatives|
|Reactivity||Human, Rat (Rattus) Alternatives|
|Conjugate||This NGFB antibody is un-conjugated Alternatives|
Western Blotting (WB)
|8 references available|
|Supplier||Log in to see|
Product Details anti-NGFB AntibodyTarget Details NGFB Application Details Handling References for anti-NGFB antibody (ABIN3043754) Images
|Purpose||Rabbit IgG polyclonal antibody for Beta-nerve growth factor(NGF) detection. Tested with WB in Human,Mouse,Rat.|
Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Rabbit IgG polyclonal antibody for Beta-nerve growth factor(NGF) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: nerve growth factor(beta polypeptide)
Protein Name: Beta-nerve growth factor(Beta-NGF)
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence at the N-terminus of human NGF(162-173aa EVNINNSVFKQY), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.|
Target Details NGFBProduct Details anti-NGFB Antibody Application Details Handling References for anti-NGFB antibody (ABIN3043754) Images back to top
|Alternative Name||NGF (NGFB Antibody Abstract)|
Nerve growth factor is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. The nucleotide sequence of human and mouse beta-NGF are very similar. The beta-subunits of nerve growth factor(NGFB) have been assigned to mouse chromosome 3 and human chromosome 1p22. The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1. A mutation in the nerve growth factor beta gene(NGFB) causes loss of pain perception.
Synonyms: Beta nerve growth factor antibody|Beta nerve growth factor precursor antibody|Beta NGF antibody|Beta-nerve growth factor antibody|Beta-NGF antibody|HSAN5 antibody|MGC161426 antibody|MGC161428 antibody|Nerve growth factor beta antibody|Nerve growth factor beta polypeptide antibody|Nerve growth factor beta subunit antibody|NGF antibody|NGF B antibody|NGF_HUMAN antibody|NGFB antibody|NID67 antibody
|Research Area||Neurology, Growth Factors|
|Pathways||NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size|
Application DetailsProduct Details anti-NGFB Antibody Target Details NGFB Handling References for anti-NGFB antibody (ABIN3043754) Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
|Restrictions||For Research Use only|
HandlingProduct Details anti-NGFB Antibody Target Details NGFB Application Details References for anti-NGFB antibody (ABIN3043754) Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.|
|Preservative||Thimerosal (Merthiolate), Sodium azide|
|Precaution of Use||This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
References for anti-NGFB antibody (ABIN3043754)Product Details anti-NGFB Antibody Target Details NGFB Application Details Handling Images back to top
|Product cited in:||
Luo, Liu, Chen, Wang, Zeng, Chen, Cheng et al.: "Nerve growth factor and inducible nitric oxide synthase expression in the mesencephalon and diencephalon, as well as visual- and auditory-related nervous tissues, in a macaque model of type 2 ..." in: Neural regeneration research, Vol. 7, Issue 4, pp. 302-7, 2015
Lu, Liu, Zhu, Xu: "Expression of nerve growth factor and hypoxia inducible factor-1? and its correlation with angiogenesis in non-small cell lung cancer." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 3, pp. 359-62, 2014
Li, Ma, Yi, Wang, Li, Liu, Sun, Chen, Yu, Li, Chen, Zhou: "The interactions between nerve growth factor and gonadotrophins in bovine oviduct." in: Animal reproduction science, Vol. 149, Issue 3-4, pp. 117-23, 2014
Huang, Zhang, Xu, Li, Zhao: "Expression of nerve growth factor in the prostate of male rats in response to chronic stress and sympathetic denervation." in: Experimental and therapeutic medicine, Vol. 8, Issue 4, pp. 1237-1240, 2014
Zhao, Ding, Guo, Chen: "Intrathecal lidocaine neurotoxicity: combination with bupivacaine and ropivacaine and effect of nerve growth factor." in: Life sciences, Vol. 112, Issue 1-2, pp. 10-21, 2014
Li, Shu, Tang, Deng, Fu, Lv: "?-Nerve growth factor attenuates hepatocyte injury induced by D-galactosamine in vitro via TrkA NGFR." in: Molecular medicine reports, Vol. 8, Issue 3, pp. 813-7, 2013
Sun, Guo, Zheng, Zhang, Li, Liu, Yin, Yang, Shu: "Increased expression of TRPV1 in the cortex and hippocampus from patients with mesial temporal lobe epilepsy." in: Journal of molecular neuroscience : MN, Vol. 49, Issue 1, pp. 182-93, 2012
Wang, Zhao, Fan, Gong, Li, Qi, Liu: "Research on the mechanism of Zuogui Pill and Yougui Pill in promoting axonal regeneration in model rats of autoimmune encephalomyelitis." in: Chinese journal of integrative medicine, Vol. 16, Issue 2, pp. 167-72, 2010
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