anti-Mouse (Murine) NGFB antibody for Functional Studies

Recommended NGFB Antibody (supplied by: Log in to see )

Antigen
Nerve Growth Factor beta (NGFB) Antibodies
  • NGFB
  • ngfb
  • ns:zft386
  • xx:zft386
  • zgc:109730
  • hsan5
  • beta-ngf
  • Ngfb
  • Beta-NGF
  • HSAN5
  • beta-NGF
  • nerve growth factor (beta polypeptide)
  • beta-Nerve growth factor
  • nerve growth factor
  • NGF
  • ngf
  • FPV072
  • FPV076
  • Ngf
Reactivity
Human, Mouse (Murine)
176
109
87
13
4
3
3
2
1
Host
Rabbit
137
57
10
3
2
2
Clonality
Polyclonal
Conjugate
This NGFB antibody is un-conjugated
18
7
7
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Enzyme Immunoassay (EIA), Western Blotting (WB)
126
123
57
29
18
16
13
12
10
8
6
4
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN318395
$ 720.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN318389 Func EIA Rabbit IgG Log in to see Polyclonal 1
1 ABIN264353 EIA Func IP Mouse IgG1 Log in to see AS18
1 ABIN264354 EIA Func Mouse IgG1 Log in to see AS21
1 ABIN596746 Func ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN264355 EIA Func Mouse IgG1 Log in to see AS22
1 ABIN210628 Func IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN233531 Func IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN293936 Func IHC ELISA WB Sheep IgG Log in to see Polyclonal
1 ABIN293938 Func ELISA WB Sheep IgG Log in to see Polyclonal
1 ABIN210221 Func ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN576606 Func ELISA Rabbit IgG Log in to see Polyclonal
1 ABIN187625 EIA Func Mouse IgG1 Log in to see AS21

General

Antigen Nerve Growth Factor beta (NGFB) Antibodies
Reactivity Human, Mouse (Murine)
(176), (109), (87), (13), (4), (3), (3), (2), (1)
Host Rabbit
(137), (57), (10), (3), (2), (2)
Clonality
Polyclonal
Conjugate This NGFB antibody is un-conjugated
(18), (7), (7), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Enzyme Immunoassay (EIA), Western Blotting (WB)
(126), (123), (57), (29), (18), (16), (13), (12), (10), (8), (6), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-NGFB Antibody

Target Details NGFB Application Details Handling References for anti-NGFB antibody (ABIN318395) Images
Specificity This antibody recognizes both the 2.5S and 7S forms of Mouse NGF beta, a secreted peptide involved in the development and maintenance of the sympathetic and sensory nervous systems. In a standard bioassay, this antibody neutralises the activity of 3.0 ng/mL NGF 2.5S when used at a concentration of around 0.5 μg/mL.
Purification Affinitv Chromatography
Immunogen Affinity purified Mouse 2.5S NGF
Isotype IgG

Target Details NGFB

Product Details anti-NGFB Antibody Application Details Handling References for anti-NGFB antibody (ABIN318395) Images back to top
Antigen
Alternative Name NGF (NGFB Antibody Abstract)
Background Nerve growth factor (NGF) is one of a family of neurotrophins that induce the survival and proliferation of neurons. In cell culture, NGF induces the formation of neurite projections and, in vivo, may stimulate the innervation of tissues. NGF plays a role in the repair, regeneration, and protection of neurons, and as such could serve as a therapeutic agent in neurodegenerative conditions such as Alzheimer's disease. NGF enhances survival, growth, neurotransmitter biosynthesis of sympathetic and sensory neurons, neurotrophic factor, cutaneous innervation, growth, differentiation and survival of B lymphocytes. It also has a possible role in allergy and tissue repair. NGF is found in the hypothalamus, pituitary, thyroid gland, testes, epididymis, vascular smooth muscle cells, fibroblasts, mast cells and eosinophils. NGF is upregulated by glutamate, vitamin D3, IL6, FGF basic, astrocyte specific IL1, TNF alpha, PDGF and TGF beta. It is downregulated by GABAergic neuronal activity, glucocorticoids and Schwann cell-specific TGF beta.Synonyms: Beta-NGF, Beta-nerve growth factor, NGFB
Gene ID 4803
NCBI Accession NP_002497
UniProt P01138
Research Area Neurology, Growth Factors
Pathways NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size

Application Details

Product Details anti-NGFB Antibody Target Details NGFB Handling References for anti-NGFB antibody (ABIN318395) Images back to top
Application Notes ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-NGFB Antibody Target Details NGFB Application Details References for anti-NGFB antibody (ABIN318395) Images back to top
Reconstitution Restore with 1.0 mL distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09 % Sodium Azide is recommended. For Functional Studies do not Add Sodium Azide.
Concentration 1.0 mg/mL
Buffer PBS, None, None
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store undiluted at -20 °C.

References for anti-NGFB antibody (ABIN318395)

Product Details anti-NGFB Antibody Target Details NGFB Application Details Handling Images back to top
Background publications

Ye, Dang, Zhang, Viet, Lam, Dolan, Gibbs, Schmidt: "Nerve growth factor links oral cancer progression, pain, and cachexia." in: Molecular cancer therapeutics, Vol. 10, Issue 9, pp. 1667-76, 2011