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anti-Human ATM antibody for Enzyme Immunoassay

Recommended ATM Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia Mutated (ATM) Antibodies
  • AI256621
  • at1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • atdc
  • ATE
  • Atm
  • ATM
  • atm
  • atm/tefu
  • C030026E19Rik
  • CG6535
  • dATM
  • Dmel\\CG6535
  • tef
  • Tefu
  • tel1
  • TEL1
  • TELO1
  • telo1
  • Xatm
Epitope
pSer1981
67
28
17
13
13
13
7
7
7
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
279
74
28
6
4
1
1
Host
Rabbit
204
52
14
8
3
Clonality
Polyclonal
Conjugate
This ATM antibody is un-conjugated
8
8
7
7
6
6
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Enzyme Immunoassay (EIA)
157
78
72
50
40
36
23
22
16
11
6
4
3
2
2
1
1
1
1
Supplier
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Catalog No. ABIN358435
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088337954 ABIN401482 EIA WB Sheep IgG pSer1981 Log in to see Polyclonal 5
0.00088337954 ABIN499359 EIA IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 1
0.00088337954 ABIN1105463 EIA WB Mouse IgG1 Log in to see 5C5 1

Top referenced anti-ATM antibody for Enzyme Immunoassay

Similar anti-ATM Antibodies

Application / Reactivity Human
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BioImaging (BI) 1 Antibodies
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Dot Blot (DB) 22 Antibodies
ELISA 78 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 6 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 25 Antibodies
Immunofluorescence (IF) 50 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies
Immunohistochemistry (IHC) 81 Antibodies
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Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 40 Antibodies
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General

Antigen Ataxia Telangiectasia Mutated (ATM) Antibodies
Epitope pSer1981
(67), (28), (17), (13), (13), (13), (7), (7), (7), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(279), (74), (28), (6), (4), (1), (1)
Host Rabbit
(204), (52), (14), (8), (3)
Clonality
Polyclonal
Conjugate This ATM antibody is un-conjugated
(8), (8), (7), (7), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA)
(157), (78), (72), (50), (40), (36), (23), (22), (16), (11), (6), (4), (3), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-ATM Antibody

Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN358435) Images
Specificity This antibody detects ABL pSer1981.
Purification Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1981 of human ATM.
Isotype Ig

Target Details ATM

Product Details anti-ATM Antibody Application Details Handling References for anti-ATM Antibody (ABIN358435) Images back to top
Antigen
Alternative Name ATM (ATM Antibody Abstract)
Background ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2,checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. ATM and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in the gene encoding ATM are associated with ataxia telangiectasia, an autosomal recessive disorder.Synonyms: A-T mutated, ATDC, Ataxia telangiectasia mutated, Serine-protein kinase ATM, TEL1, TELO1
Molecular Weight 350644 Da
Gene ID 472, 9606
UniProt Q13315
Research Area Cancer, DNA/RNA
Pathways p53 Signaling, Apoptosis, DNA Damage Repair

Application Details

Product Details anti-ATM Antibody Target Details ATM Handling References for anti-ATM Antibody (ABIN358435) Images back to top
Application Notes ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-ATM Antibody Target Details ATM Application Details References for anti-ATM Antibody (ABIN358435) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-ATM Antibody (ABIN358435)

Product Details anti-ATM Antibody Target Details ATM Application Details Handling Images back to top
Background publications

Brunet, Gutiérrez-Enríquez, Torres, Bérez, Sanjosé, Galceran, Izquierdo, Menéndez, Gumà, Borràs: "ATM germline mutations in Spanish early-onset breast cancer patients negative for BRCA1/BRCA2 mutations." in: Clinical genetics, Vol. 73, Issue 5, pp. 465-73, 2008

Tsai, Chung, Takahashi, Xu, Hu: "Functional interaction between FOXO3a and ATM regulates DNA damage response." in: Nature cell biology, Vol. 10, Issue 4, pp. 460-7, 2008

Images

Product Details anti-ATM Antibody Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN358435) back to top
Supplier Images
 image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (pSer1981) (ABIN358435) anti-Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibody