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anti-Monkey BAX antibody for Flow Cytometry

Recommended BAX Antibody (supplied by: Log in to see )

Antigen
BCL2-Associated X Protein (BAX) Antibodies
  • BAX
  • bax
  • bax-A
  • BAX-ALPHA
  • BCL2L4
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • xBax
  • xlbax
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
489
165
153
64
23
22
13
9
3
2
2
2
1
1
Host
Mouse
317
211
4
Clonality
Monoclonal
Conjugate
This BAX antibody is un-conjugated
19
14
13
10
8
7
7
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
1
Application
Flow Cytometry (FACS)
387
201
152
144
137
128
97
65
55
34
6
6
2
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN2666260
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010485103 ABIN2666261 FACS Mouse IgG1 kappa Log in to see 6A7 6
0.0010485103 ABIN4283104 FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283105 FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283106 FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283112 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Alexa Fluor 405 Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283113 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Alexa Fluor 488 Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283114 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Alexa Fluor 647 Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283115 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Alexa Fluor 700 Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283116 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Allophycocyanin Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283117 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Biotin Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283118 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 650 Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283119 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 680 Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283120 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 488 Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283122 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 755 Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283123 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB PerCP Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283124 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB PE Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283125 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 550 Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283126 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 350 Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283127 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 405 Mouse IgG1 kappa AA 3-16 Log in to see 2D2
0.0010485103 ABIN4283128 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 405LS Mouse IgG1 kappa AA 3-16 Log in to see 2D2

Top referenced anti-BAX antibody for Flow Cytometry

Similar anti-BAX Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Monkey
Western Blotting (WB) 354 Antibodies 107 Antibodies 91 Antibodies 56 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 113 Antibodies 49 Antibodies 32 Antibodies 23 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 135 Antibodies 26 Antibodies 22 Antibodies 48 Antibodies
Immunohistochemistry (IHC) 144 Antibodies 59 Antibodies 56 Antibodies 27 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 50 Antibodies

General

Antigen BCL2-Associated X Protein (BAX) Antibodies
Reactivity Human, Monkey, Mouse (Murine), Rat (Rattus)
(489), (165), (153), (64), (23), (22), (13), (9), (3), (2), (2), (2), (1), (1)
Host Mouse
(317), (211), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This BAX antibody is un-conjugated
(19), (14), (13), (10), (8), (7), (7), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1)
Application Flow Cytometry (FACS)
(387), (201), (152), (144), (137), (128), (97), (65), (55), (34), (6), (6), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-BAX Antibody

Target Details BAX Application Details Handling References for anti-BAX Antibody (ABIN2666260) Images
Purification The antibody was purified by affinity chromatography.
Clone 6A7
Isotype IgG1 kappa

Target Details BAX

Product Details anti-BAX Antibody Application Details Handling References for anti-BAX Antibody (ABIN2666260) Images back to top
Antigen
Alternative Name Bax (BAX Antibody Abstract)
Background Bax is a 21 kD pro-apoptotic protein known to regulate apoptosis. Bax is found in the cytoplasm, mitochondria, and nucleus and is highly expressed in hematopoietic stem cells, the ovary, and in the lymph node. Bax binds the anti-apoptotic protein Bcl-2 as a heterodimer or forms homodimers. The relative levels of pro-apoptotic proteins such as Bax and anti-apoptotic proteins such as Bcl-2 determines whether cell death will occur following an apoptotic stimulus. Bax accelerates the opening of mitochondrial VDAC altering membrane potential and allowing cytochrome c to pass out of the mitochondria into the cytosol to initiate downstream caspase activation. p53 can transcriptionally activate the Bax gene to induce apoptosis. Bax has been shown to be mutated in some human cancers. Clone 2D2 has been shown to be useful for western blotting, immunoprecipitation, immunofluorescence and immunohistochemistry of the human Bax protein.This antibody does not cross-react with Bcl-2 or Bcl-XL proteins.
Research Area Cancer, Apoptosis/Necrosis
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-BAX Antibody Target Details BAX Handling References for anti-BAX Antibody (ABIN2666260) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-BAX Antibody Target Details BAX Application Details References for anti-BAX Antibody (ABIN2666260) Images back to top
Concentration 0.5 mg/mL
Buffer phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Upon receipt, store undiluted at between 2°C and 8°C.

References for anti-BAX Antibody (ABIN2666260)

Product Details anti-BAX Antibody Target Details BAX Application Details Handling Images back to top
Background publications

Liu, Bi, Wang, Shen, Zhang, Yang, Wang, Liu, Lu, Han: "Kinase AKT1 negatively controls neutrophil recruitment and function in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 5, pp. 2680-90, 2013

LeBlanc, Lawrence, Varfolomeev, Totpal, Morlan, Schow, Fong, Schwall, Sinicropi, Ashkenazi: "Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax." in: Nature medicine, Vol. 8, Issue 3, pp. 274-81, 2002

Marzo, Brenner, Zamzami, Jürgensmeier, Susin, Vieira, Prévost, Xie, Matsuyama, Reed, Kroemer: "Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis." in: Science (New York, N.Y.), Vol. 281, Issue 5385, pp. 2027-31, 1998

Hsu, Youle: "Nonionic detergents induce dimerization among members of the Bcl-2 family." in: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13829-34, 1997

Miyashita, Reed: "Tumor suppressor p53 is a direct transcriptional activator of the human bax gene." in: Cell, Vol. 80, Issue 2, pp. 293-9, 1995

Oltvai, Milliman, Korsmeyer: "Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death." in: Cell, Vol. 74, Issue 4, pp. 609-19, 1993

Images

Product Details anti-BAX Antibody Target Details BAX Application Details Handling References for anti-BAX Antibody (ABIN2666260) back to top
Supplier Images
Western Blotting (WB) image for anti-BAX antibody (BCL2-Associated X Protein) (ABIN2666260) anti-BCL2-Associated X Protein (BAX) antibody