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CHEK1 Proteins

(Checkpoint Kinase 1 (CHEK1))
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].

13 results

custom-made CHEK1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7562295
 
custom-made CHEK1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7553430
 
CHEK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Catalog No. ABIN1349301
 
CHEK1 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7317105
 
CHEK1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
Catalog No. ABIN7320012
 
CHEK1 Origin: Human Host: Insect Cells Recombinant 70 % - 90 % Func Active
Catalog No. ABIN5508870
 
CHEK1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7405831
 
custom-made CHEK1 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
Catalog No. ABIN3131495
 
custom-made CHEK1 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
Catalog No. ABIN3091648
 
CHEK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713978
 
CHEK1 Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7590920
 
CHEK1 Origin: Chicken Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1625325
 
CHEK1 Origin: Schizosaccharomyces pombe Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1476618
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Chicken
    • Rat
    • Schizosaccharomyces pombe
  • Images available
  • Carrier free only
  • Host
    • HEK-293 Cells
    • Yeast
    • Baculovirus infected Insect Cells
    • Cell-free protein synthesis (CFPS)
    • Escherichia coli (E. coli)
    • Insect Cells
    • Wheat germ
  • Binding Specificity
    • AA 1-476
    • AA 1-496
    • AA 194-446
    • Transcript Variant 3
  • Conjugate
    • His tag
    • GST tag
    • Strep Tag
    • GST tag,His tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
    • Frozen
  • Biological Activity
    • Biologically Active
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • CUSABIO
    • OriGene

Latest Publications for our CHEK1 Proteins

Larsen, Rampalli, Burns, Brunette, Dilworth, Megeney: "Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 9, pp. 4230-5, (2010) (PubMed).

Aliases for CHEK1 Proteins

checkpoint kinase 1 (CHEK1) Proteins
serine/threonine-protein kinase chk1 (ANI_1_2436074) Proteins
serine/threonine-protein kinase chk1 (AOR_1_768154) Proteins
serine/threonine-protein kinase Chk1 (PTRG_04183) Proteins
CAMK/CAMKL/CHK1 protein kinase Chk1 (SJAG_01680) Proteins
serine/threonine-protein kinase chk1 (PAAG_04978) Proteins
serine/threonine-protein kinase chk1 (MCYG_03290) Proteins
serine/threonine-protein kinase chk1 (VDBG_03742) Proteins
checkpoint kinase 1 S homeolog (chek1.S) Proteins
checkpoint kinase 1 (Chek1) Proteins
checkpoint kinase 1 (chek1) Proteins
An08g10320 Proteins
AO090003000441 Proteins
C85740 Proteins
CHEK1 Proteins
CHK1 Proteins
chk1 Proteins
Chk1 Proteins
id:ibd2720 Proteins
rad27 Proteins
zgc:56093 Proteins
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