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anti-Human KAT2B antibody for Enzyme Immunoassay

Recommended KAT2B Antibody (supplied by: Log in to see )

Antigen
K(lysine) Acetyltransferase 2B (KAT2B) Antibodies
  • A930006P13Rik
  • AI461839
  • AW536563
  • CAF
  • gb:dq017634
  • im:7156024
  • P
  • p/CAF
  • P/CAF
  • PCAF
  • Pcaf
  • pcaf
  • si:ch211-1j13.2
  • zgc:161980
Epitope
C-Term, AA 802-832
17
15
13
9
9
5
5
4
3
3
3
2
2
2
1
1
1
1
Reactivity
Human
99
35
26
4
3
2
2
1
Host
Rabbit
69
31
Clonality
Polyclonal
Conjugate
This KAT2B antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
75
42
16
11
7
4
4
3
1
1
Supplier
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Catalog No. ABIN954021
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088668795 ABIN954022 EIA WB Rabbit Ig N-Term, AA 260-291 Log in to see Polyclonal 3
0.00088668795 ABIN271904 EIA IHC (p) WB Rabbit Log in to see Polyclonal
0.00088668795 ABIN2728342 EIA Rabbit IgG Log in to see Polyclonal

Top referenced anti-KAT2B antibody for Enzyme Immunoassay

Similar anti-KAT2B Antibodies

Application / Reactivity Human
Chromatin Immunoprecipitation (ChIP) 1 Antibodies
Dot Blot (DB) 1 Antibodies
ELISA 42 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 16 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies
Immunoprecipitation (IP) 4 Antibodies
RNA Interference (RNAi) 1 Antibodies
Western Blotting (WB) 77 Antibodies

General

Antigen K(lysine) Acetyltransferase 2B (KAT2B) Antibodies
Epitope C-Term, AA 802-832
(17), (15), (13), (9), (9), (5), (5), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human
(99), (35), (26), (4), (3), (2), (2), (1)
Host Rabbit
(69), (31)
Clonality
Polyclonal
Conjugate This KAT2B antibody is un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(75), (42), (16), (11), (7), (4), (4), (3), (1), (1)
Pubmed 3 references available
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Product Details anti-KAT2B Antibody

Target Details KAT2B Application Details Handling References for anti-KAT2B Antibody (ABIN954021) Images
Specificity This antibody reacts to PCAF.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Immunogen KLH conjugated synthetic peptide between 802-832 amino acids from the C-terminal region of human PCAF
Isotype Ig

Target Details KAT2B

Product Details anti-KAT2B Antibody Application Details Handling References for anti-KAT2B Antibody (ABIN954021) Images back to top
Antigen
Alternative Name PCAF / KAT2B (KAT2B Antibody Abstract)
Background CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.Synonyms: Histone acetylase PCAF, Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Lysine acetyltransferase 2B, P/CAF, P300/CBP-associated factor
Molecular Weight 93013 Da
Gene ID 8850
NCBI Accession NP_003875
Pathways p53 Signaling

Application Details

Product Details anti-KAT2B Antibody Target Details KAT2B Handling References for anti-KAT2B Antibody (ABIN954021) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-KAT2B Antibody Target Details KAT2B Application Details References for anti-KAT2B Antibody (ABIN954021) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-KAT2B Antibody (ABIN954021)

Product Details anti-KAT2B Antibody Target Details KAT2B Application Details Handling Images back to top
Background publications

Perez, Knights, Sahu, Catania, Kolukula, Stoler, Graessmann, Ogryzko, Pishvaian, Albanese, Avantaggiati: "Restoration of DNA-binding and growth-suppressive activity of mutant forms of p53 via a PCAF-mediated acetylation pathway." in: Journal of cellular physiology, Vol. 225, Issue 2, pp. 394-405, 2010

Mooney, Goel, DAssoro, Salisbury, Janknecht: "Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30443-52, 2010

Aoyama, Okamoto, Fukiage, Otsuka, Furu, Ito, Jin, Ueda, Nagayama, Nakayama, Nakamura, Toguchida: "Histone modifiers, YY1 and p300, regulate the expression of cartilage-specific gene, chondromodulin-I, in mesenchymal stem cells." in: The Journal of biological chemistry, Vol. 285, Issue 39, pp. 29842-50, 2010

Images

Product Details anti-KAT2B Antibody Target Details KAT2B Application Details Handling References for anti-KAT2B Antibody (ABIN954021) back to top
Supplier Images
Western Blotting (WB) image for anti-KAT2B antibody (K(lysine) Acetyltransferase 2B) (C-Term) (ABIN954021) PCAF Antibody (C-term) western blot analysis in U251 cell line lysates (35µg/lane).Th...