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Browse our anti-p300 (EP300) Antibodies

Full name:
anti-E1A Binding Protein P300 Antibodies (EP300)
On are 270 E1A Binding Protein P300 (EP300) Antibodies from 22 different suppliers available. Additionally we are shipping p300 Kits (16) and p300 Proteins (9) and many more products for this protein. A total of 311 p300 products are currently listed.
A430090G16, A730011L11, KAT3B, p300, p300 HAT, RSTS2
list all antibodies Gene Name GeneID UniProt
EP300 2033 Q09472
EP300 328572  
EP300 170915  

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All available anti-p300 Antibodies

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Top referenced anti-p300 Antibodies

  1. Human Monoclonal p300 Primary Antibody for ChIP, EM - ABIN152047 : Eckner, Ludlow, Lill, Oldread, Arany, Modjtahedi, DeCaprio, Livingston, Morgan: Association of p300 and CBP with simian virus 40 large T antigen. in Molecular and cellular biology 1996 (PubMed)
    Show all 8 references for ABIN152047

  2. Human Polyclonal p300 Primary Antibody for EIA, IHC (p) - ABIN358187 : Finlan, Hupp: The N-terminal interferon-binding domain (IBiD) homology domain of p300 binds to peptides with homology to the p53 transactivation domain. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358187

  3. Human Monoclonal p300 Primary Antibody for FACS, ICC - ABIN151948 : Eckner, Yao, Oldread, Livingston: Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. in Genes & development 1996 (PubMed)
    Show all 5 references for ABIN151948

  4. Human Monoclonal p300 Primary Antibody for ChIP, ICC - ABIN152048 : Eckner, Ewen, Newsome, Gerdes, DeCaprio, Lawrence, Livingston: Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. in Genes & development 1994 (PubMed)
    Show all 4 references for ABIN152048

  5. Human Monoclonal p300 Primary Antibody for IP, WB - ABIN967440 : Rikitake, Moran: DNA-binding properties of the E1A-associated 300-kilodalton protein. in Molecular and cellular biology 1992 (PubMed)
    Show all 3 references for ABIN967440

  6. Human Polyclonal p300 Primary Antibody for EIA - ABIN358269 : Subbaramaiah, Hudis, Chang, Hla, Dannenberg: EP2 and EP4 receptors regulate aromatase expression in human adipocytes and breast cancer cells. Evidence of a BRCA1 and p300 exchange. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for ABIN358269

  7. Human Polyclonal p300 Primary Antibody for DB, IHC (p) - ABIN389618 : Kung, Zabludoff, France, Freedman, Tanner, Vieira, Cornell-Kennon, Lee, Wang, Wang, Memmert, Naegeli, Petersen, Eck, Bair, Wood, Livingston: Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway. in Cancer cell 2004 (PubMed)
    Show all 2 references for ABIN389618

  8. Human Monoclonal p300 Primary Antibody for IHC (fro), IF - ABIN180371 : Dallas, Yaciuk, Moran: Characterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexes. in Journal of virology 1997 (PubMed)
    Show all 2 references for ABIN180371

  9. Human Polyclonal p300 Primary Antibody for IHC, ELISA - ABIN1531355 : Dunham, Shimizu, Roe, Chissoe, Hunt, Collins, Bruskiewich, Beare, Clamp, Smink, Ainscough, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beasley, Bird, Blakey, Bridgeman, Buck, Burgess, Burrill et al.: The DNA sequence of human chromosome 22. ... in Nature 1999 (PubMed)

  10. Human Polyclonal p300 Primary Antibody for DB, IHC (p) - ABIN389698 : Aubry, Shin, Crary, Lefort, Qureshi, Lefebvre, Califano, Shelanski: Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression. in PLoS ONE 2015 (PubMed)

More Antibodies against p300 Interaction Partners

Human E1A Binding Protein P300 (EP300) interaction partners

  1. 2-O, 3-O desulfated heparin inhibited HMGB1 (show HMGB1 Antibodies) release, at least in part, by direct molecular inhibition of p300 HAT activity.

  2. Shikonin induces apoptosis in some lung cancer cells via activation of FOXO3a (show FOXO3 Antibodies)/EGR1 (show EGR1 Antibodies)/SIRT1 (show SIRT1 Antibodies) signaling, and AKT (show AKT1 Antibodies) and p300 negatively regulate this process via Bim (show BCL2L11 Antibodies) upregulation.

  3. A potential mechanism for the role of Sirt1 (show SIRT1 Antibodies) in lung fibrosis was through regulating the expression of p300. Thus, we characterized Sirt1 (show SIRT1 Antibodies) as an important regulator of lung fibrosis and provides a proof of principle for activation or overexpression of Sirt1 (show SIRT1 Antibodies) as a potential novel therapeutic strategy for IPF.

  4. Results suggest that increase in nuclear expression of p300, as well as the presence of cytoplasmic but loss of nuclear expression of p300/CBP-associated factor (PCAF (show KAT2B Antibodies)), could play an important role in the development and progression of cutaneous squamous cell carcinomas (SCC (show CYP11A1 Antibodies)).

  5. Acetylation of lysine 109 modulates PXR (show NR1I2 Antibodies) DNA binding and transcriptional activity; PXR (show NR1I2 Antibodies) acetylation status and transcriptional activity are modulated by E1A binding protein (p300) and SIRT1 (show SIRT1 Antibodies).

  6. We show that a DUX4 minigene, bearing only the homeodomains and C-terminus, is transcriptionally functional and cytotoxic, and that overexpression of a nuclear targeted C-terminus impairs the ability of WT DUX4 to interact with p300 and to regulate target genes.

  7. These results suggest that OCT (show Plxna2 Antibodies) attenuates SGC (show SGCB Antibodies)-7901 cell proliferation by enhancing P300-HAT activity through the interaction of ZAC (show PLAGL1 Antibodies) and P300, causing a reduction in pS10-H3 and an increase in acK14-H3. These findings provide insight for future research on OCT (show Plxna2 Antibodies) and further demonstrate the potential of OCT (show Plxna2 Antibodies) to be used as a therapeutic agent for gastric cancer

  8. C646 treatment attenuated ETV1 (show ETV1 Antibodies) protein expression and inactivated KIT-dependent pathways. Taken together, the present study suggests that CBP/p300 (show CREBBP Antibodies) may serve as novel antineoplastic targets and that use of the selective HAT (show MGEA5 Antibodies) inhibitor C646 is a promising antitumor strategy for Gastrointestinal stromal tumors.

  9. High p300 expression is associated with migratory and invasive behavior in pancreatic cancer.

  10. Data show that HTLV-1 basic leucine zipper (bZIP) factor (HBZ (show HBZ Antibodies)) represses p53 (show TP53 Antibodies) activity by direct inhibition of the histone acetyltransferase (HAT (show HAT Antibodies)) activity of p300/CBP (show CREBBP Antibodies) and the HAT (show MGEA5 Antibodies) activity of HBO1 (show MYST2 Antibodies): [HBZ (show HBZ Antibodies)]

Mouse (Murine) E1A Binding Protein P300 (EP300) interaction partners

  1. 2-O, 3-O desulfated heparin inhibited HMGB1 (show HMGB1 Antibodies) release, at least in part, by direct molecular inhibition of p300 HAT activity.

  2. work shows that helenalin acetate inhibits C/EBPbeta (show CEBPB Antibodies) by binding to the N-terminal part of C/EBPbeta (show CEBPB Antibodies), thereby disrupting the cooperation of C/EBPbeta (show CEBPB Antibodies) with the co-activator p300 (show NOTCH1 Antibodies).

  3. STAT6 (show STAT6 Antibodies) mediates the CT-induced TIM4 (show TIMD4 Antibodies) expression in DCs. In conclusion, p300 (show NOTCH1 Antibodies) and STAT6 (show STAT6 Antibodies) mediate the microbial product CT-induced TIM4 (show TIMD4 Antibodies) expression in DCs.

  4. Findings indicate that E1a-binding protein (p300) is not required for the normal development or functioning of skeletal muscle.

  5. Hdac3 (show HDAC3 Antibodies) cooperates with p300 (show NOTCH1 Antibodies) to prime and maintain oligodendrocyte identity

  6. p300 (show NOTCH1 Antibodies) histone acetyltransferase (show HAT Antibodies) activity is critical for Wnt (show WNT2 Antibodies)-dependent palate mesenchymal cell proliferation and migration, both processes that play a significant role in morphogenesis of the palate.

  7. Data indicate that glucose-induced endothelial to mesenchymal transition in vivo and in vitro in the hearts of diabetic mice is possibly mediated by miR (show MLXIP Antibodies)-200b and p300 (show NOTCH1 Antibodies).

  8. This study demonstrated that p300 (show NOTCH1 Antibodies) increase in skeletal muscle in muscle atrophy.

  9. This study demonstrates that p300 (show NOTCH1 Antibodies) mediates histone acetylation of PS1 (show PSEN1 Antibodies) and BACE1 (show BACE Antibodies) in a cellular model of Alzheimer's disease.

  10. p300 (show NOTCH1 Antibodies) regulates a number of critical signaling pathways that control liver functions.

p300 (EP300) Antigen Profile

Antigen Summary

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

Alternative names and synonyms associated with p300 (EP300)

  • E1A binding protein p300 (EP300) antibody
  • E1A-associated protein p300 (ep300) antibody
  • E1A binding protein p300 (ep300) antibody
  • E1A binding protein p300 (Ep300) antibody
  • A430090G16 antibody
  • A730011L11 antibody
  • KAT3B antibody
  • p300 antibody
  • p300 HAT antibody
  • RSTS2 antibody

Protein level used designations for EP300

histone acetyltransferase p300 , histone acetyltransferase , E1A binding protein p300 , histone acetyltransferase p300-like , E1A-associated protein p300 , E1A-binding protein, 300kD , p300 HAT

100055626 Equus caballus
458862 Pan troglodytes
706258 Macaca mulatta
446056 Takifugu rubripes
100028102 Monodelphis domestica
100455260 Pongo abelii
100468694 Ailuropoda melanoleuca
100543704 Meleagris gallopavo
100566746 Anolis carolinensis
2033 Homo sapiens
328572 Mus musculus
418000 Gallus gallus
100684945 Canis lupus familiaris
100156226 Sus scrofa
170915 Rattus norvegicus
100734820 Cavia porcellus
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